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Keywords: Bioequivalence
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Journal Articles
Skin Pharmacol Physiol (2012) 25 (5): 269–280.
Published Online: 27 July 2012
...P.A. Lehman; T.J. Franz Purpose: To develop a simple pharmacodynamic (PD) assay for the evaluation of the bioequivalence of topically applied retinoid products. Methods: Daily applications of products containing tretinoin or adapalene were made to the forearms of human subjects for up to 21 days...
Journal Articles
Skin Pharmacol Physiol (2011) 24 (4): 224–230.
Published Online: 31 March 2011
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Percutaneous absorption In vitro-in vivo correlation Bioavailability Bioequivalence...
Journal Articles
Journal Articles
Journal Articles
Skin Pharmacol Physiol (2009) 22 (5): 276–286.
Published Online: 26 August 2009
...T.J. Franz; P.A. Lehman; S.G. Raney Background: Establishing the bioequivalence of topical drug products is a costly and time-consuming process since, with few exceptions, clinical efficacy trials are required. Objective: To develop a surrogate for clinical bioequivalence testing through evaluation...
Journal Articles
Skin Pharmacology (1992) 5 (3): 129–145.
Published Online: 31 March 2009
...S. Borsadia; A.H. Ghanem; Y. Seta; W.I. Higuchi; G.L. Flynn; C.R. Behl; V.P. Shah In this paper, an attempt is made to find functional definitions of bioavailability and bioequivalence for topical products and to examine critical factors that influence topical bioavailability and bioequivalence...
Journal Articles
Skin Pharmacology (1993) 6 (1): 72–80.
Published Online: 31 March 2009
... in the evaluation of topical dermatological products with respect to bioequivalence and quality control are also discussed. Topical dermatological products Development of dermatological products Dermatological products Transdermal products Bioequivalence Quality control © 1993 S. Karger AG, Basel 1993...
Journal Articles
Journal Articles
Skin Pharmacology and Applied Skin Physiology (2001) 14 (Suppl. 1): 82–86.
Published Online: 17 November 2004
...Y.N. Kalia; I. Alberti; A. Naik; R.H. Guy We present a method to determine the cutaneous bioavailability and hence to evaluate the bioequivalence of topically applied drugs in vivo. The procedure uses serial tape-stripping and transepidermal water loss measurements to quantify the thickness...