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Keywords: Barrier function
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Journal Articles
Journal Articles
Skin Pharmacol Physiol (2021) 34 (1): 38–50.
Published Online: 10 February 2021
... of the cornified envelope. The CLE is essential for proper barrier function of the skin and is derived from linoleate-rich acylglucosylceramides synthesized in the viable epidermis. Biosynthesis of acylglucosylceramide and its conversion to the cornified envelope is complex. Acylglucosylceramide in the bounding...
Journal Articles
Skin Pharmacol Physiol (2018) 32 (1): 1–7.
Published Online: 18 October 2018
... from any ideas, methods, instructions or products referred to in the content or advertisements. Antihistamines Atopic dermatitis Barrier function Barrier response Ceramides Cytokines Epidermal lipids Kallikreins Moisturizers PPAR pH By definition, moisturizers contain...
Journal Articles
Skin Pharmacol Physiol (2016) 29 (5): 231–242.
Published Online: 23 August 2016
... extracted from HaCaT keratinocytes was determined by gas chromatography/mass spectrometry. Regulation of FA synthesis was analyzed by real-time PCR. For physiological analysis, excised mouse skin was glycated using a vertical diffusion cell and used for the evaluation of barrier function by transepidermal...
Journal Articles
Skin Pharmacol Physiol (2013) 26 (2): 85–91.
Published Online: 16 January 2013
... [ 4,6 ]. Barrier function Occlusion Percutaneous absorption-penetration in vivo Stratum corneum Octanol-water partition coefficient Hydrophilicity Liphophilicity © 2013 S. Karger AG, Basel 2013 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...
Journal Articles
Skin Pharmacol Physiol (2011) 25 (1): 25–33.
Published Online: 07 September 2011
... elements. Regional differences in skin functions are well known. The aim of the present study was to assess and compare skin physiological parameters in vivo at 16 anatomical sites: Barrier function in terms of transepidermal water loss (TEWL), stratum corneum (SC) hydration (assessed by capacitance), skin...
Journal Articles
Journal Articles
Skin Pharmacol Physiol (2010) 23 (4): 193–200.
Published Online: 25 February 2010
...J. Liu; W.Y. Man; C.Z. Lv; S.P. Song; Y.J. Shi; P.M. Elias; M.Q. Man Background/Objectives: Prior studies have demonstrated that both the skin surface pH and epidermal permeability barrier function vary with skin pigmentation types. Although melanin deficiency is the main feature of vitiligo...
Journal Articles
Skin Pharmacol Physiol (2009) 22 (4): 178–189.
Published Online: 31 July 2009
... 19, 2009 Published online: July 31, 2009 Barrier Functions of Human Skin: A Holistic View G.K. Menona A.M. Kligmanb aGlobal R&D, ISP Corporation, Wayne, N.J., and bDepartment of Dermatology, University of Pennsylvania, Philadelphia, Pa., USA Key Words Barrier function Stratum corneum Stratum...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Skin Pharmacology (1992) 5 (1): 49–56.
Published Online: 31 March 2009
... keratohyalin granules and intra- and extracellular membrane-coating granules are observed. After 7 days of culture, a compact stratum corneum covers the reconstructed epidermis. In the present work, the barrier function of the reconstructed epidermis was evaluated by measuring fluxes of 3 H-water. Our results...
Journal Articles
Skin Pharmacol Physiol (2009) 22 (3): 131–136.
Published Online: 09 January 2009
... in this study. Basal skin surface pH, SC hydration, permeability barrier function as well as barrier recovery rates were measured over previously involved skin sites with a skin physiology monitor. One-way ANOVA and two-tailed Student’s t test were used to determine the significance between 2 groups and 3...
Journal Articles
Skin Pharmacol Physiol (2008) 21 (3): 124–135.
Published Online: 03 June 2008
... reaction. In vivo, different non-invasive parameters for the evaluation of skin irritation and irritant potential of compounds and their specific formulations have been introduced, such as epidermal barrier function, skin hydration, surface pH, lipid composition, skin colour and skin blood flow...
Journal Articles
Skin Pharmacol Physiol (2006) 19 (6): 296–302.
Published Online: 24 November 2006
..., instructions or products referred to in the content or advertisements. Acid mantle Barrier function Skin cleansing Skin pH Synthetic detergents Review Skin Pharmacol Physiol 2006;19:296 302 DOI: 10.1159/000094670 Received: September 2, 2005 Accepted after revision: December 22, 2005 Published...
Journal Articles
Skin Pharmacol Physiol (2006) 19 (4): 182–189.
Published Online: 14 July 2006
... from any ideas, methods, instructions or products referred to in the content or advertisements. Circadian rhythm Biological clock Seasonal variation/circaannual rhythm Barrier function Stratum corneum pH Review Skin Pharmacol Physiol 2006;19:182 189 DOI: 10.1159/000093113 Received: June 6...
Journal Articles
Skin Pharmacology and Applied Skin Physiology (2001) 14 (Suppl. 1): 52–62.
Published Online: 17 November 2004
... for Electron Microscopy, Leiden University Medical Center, Leiden, The Netherlands Key Words Stratum corneum W Barrier function W Lipid organization W Lipid composition Abstract In the superficial layer of the skin, the stratum corneum (SC), the lipids form two crystalline lamellar phases with periodicities...
Journal Articles
Skin Pharmacology and Applied Skin Physiology (2001) 14 (Suppl. 1): 63–71.
Published Online: 17 November 2004
...M. Ponec; S. Gibbs; G. Pilgram; E. Boelsma; H. Koerten; J. Bouwstra; M. Mommaas One of the prerequisites for the use of human skin equivalents for scientific and screening purposes is that their barrier function is similar to that of native skin. Using human epidermis reconstructed on de...
Journal Articles
Skin Pharmacology and Applied Skin Physiology (2001) 14 (Suppl. 1): 72–81.
Published Online: 17 November 2004
... determinants Enhancers Retarders Stratum corneum Barrier function Skin Pharmacol Appl Skin Physiol 2001;14(suppl 1):72 81 Modulation of the Barrier Function of the Skin J. Hadgraft Medway Sciences, NRI University of Greenwich, Chatham Maritime, UK Key Words Skin penetration W Physicochemical...