Abstract
Background: About 50% of the sun’s radiation arriving on earth is visible light (VIS). For a long time, its effects on human health have not been fully investigated. But recently, the influence of VIS has gained more attention, especially regarding skin physiology. Studies showed various effects, many of them harmful, comparable to UV radiation. As a result, there are now a few sunscreens commercially available which claim protection against VIS. The question of whether protection is necessary is still much discussed. Aims: The objective of this study was to develop an easy-to-perform high-energy visible (HEV) and low-end visible (LEV) light transmittance method to determine the direct VIS protection of sunscreens and other cosmetic samples. Furthermore, the influence of the brightness of the tested products on the HEV, LEV, and infrared A protection was investigated. Methods: An experimental setup consisting of a light source, a VIS-transmissible filter system, and a sensor unit was built to measure the direct VIS protection of sunscreens and other daily skin care products in two ranges of the VIS area. For a closer look, the brightness of the samples was evaluated by photometric assessment. Results/Conclusion: The experimental setup could be validated. It could be demonstrated for the first time that there is a strong positive linear correlation between transmittance and brightness of tinted sunscreen and daily skin care products with sunscreen properties in the HEV, LEV, and infrared A range. However, tinted samples worked best in the blue light region, and the higher the wavelength range, the lower the protection.
References
1.
van der Pols
JC
, Xu
C
, Boyle
GM
, Parsons
PG
, Whiteman
DC
, Green
AC
. Expression of p53 tumor suppressor protein in sun-exposed skin and associations with sunscreen use and time spent outdoors: a community-based study
. Am J Epidemiol
. 2006
Jun
;163
(11
):982
–8
.
[PubMed]
0002-92622.
Hughes
MC
, Williams
GM
, Baker
P
, Green
AC
. Sunscreen and prevention of skin aging: a randomized trial
. Ann Intern Med
. 2013
Jun
;158
(11
):781
–90
.
[PubMed]
0003-48193.
Green
AC
, McBride
P
. Squamous cell carcinoma of the skin (non-metastatic)
. BMJ Clin Evid
; 2014
.4.
Mahmoud
BH
, Ruvolo
E
, Hexsel
CL
, Liu
Y
, Owen
MR
, Kollias
N
, et al Impact of long-wavelength UVA and visible light on melanocompetent skin
. J Invest Dermatol
. 2010
Aug
;130
(8
):2092
–7
.
[PubMed]
0022-202X5.
Regazzetti
C
, Sormani
L
, Debayle
D
, Bernerd
F
, Tulic
MK
, De Donatis
GM
, et al Melanocytes sense blue light and regulate pigmentation through opsin-3
. J Invest Dermatol
. 2018
Jan
;138
(1
):171
–8
.
[PubMed]
0022-202X6.
Mahmoud
BH
, Hexsel
CL
, Hamzavi
IH
, Lim
HW
. Effects of visible light on the skin
. Photochem Photobiol
. 2008
Mar-Apr
;84
(2
):450
–62
.
[PubMed]
0031-86557.
Liebel
F
, Kaur
S
, Ruvolo
E
, Kollias
N
, Southall
MD
. Irradiation of skin with visible light induces reactive oxygen species and matrix-degrading enzymes
. J Invest Dermatol
. 2012
Jul
;132
(7
):1901
–7
.
[PubMed]
0022-202X8.
Bessho
T
, Tano
K
, Nishmura
S
, Kasai
H
. Induction of mutations in mouse FM3A cells by treatment with riboflavin plus visible light and its possible relation with formation of 8-hydroxyguanine (7,8-dihydro-8-oxoguanine) in DNA
. Carcinogenesis
. 1993
May
;14
(5
):1069
–71
.
[PubMed]
0143-33349.
Kielbassa
C
, Roza
L
, Epe
B
. Wavelength dependence of oxidative DNA damage induced by UV and visible light
. Carcinogenesis
. 1997
Apr
;18
(4
):811
–6
.
[PubMed]
0143-333410.
Ennever
JF
. Blue light, green light, white light, more light: treatment of neonatal jaundice
. Clin Perinatol
. 1990
Jun
;17
(2
):467
–81
.
[PubMed]
0095-510811.
Kwon
HH
, Lee
JB
, Yoon
JY
, Park
SY
, Ryu
HH
, Park
BM
, et al The clinical and histological effect of home-use, combination blue-red LED phototherapy for mild-to-moderate acne vulgaris in Korean patients: a double-blind, randomized controlled trial
. Br J Dermatol
. 2013
May
;168
(5
):1088
–94
.
[PubMed]
0007-096312.
Mackert
A
, Volz
HP
, Stieglitz
RD
, Müller-Oerlinghausen
B
. Phototherapy in nonseasonal depression
. Biol Psychiatry
. 1991
Aug
;30
(3
):257
–68
.
[PubMed]
0006-322313.
Gysin
F
, Gysin
F
, Gross
F
. [Winter depression and phototherapy. The state of the art]
. Acta Med Port
. 1997
Dec
;10
(12
):887
–93
.
[PubMed]
0870-399X14.
Huang
Z
. A review of progress in clinical photodynamic therapy
. Technol Cancer Res Treat
. 2005
Jun
;4
(3
):283
–93
.
[PubMed]
1533-034615.
Nakashima
Y
, Ohta
S
, Wolf
AM
. Blue light-induced oxidative stress in live skin
. Free Radic Biol Med
. 2017
Jul
;108
:300
–10
.
[PubMed]
0891-584916.
Vandersee
S
, Beyer
M
, Lademann
J
, Darvin
ME
. Blue-violet light irradiation dose dependently decreases carotenoids in human skin, which indicates the generation of free radicals
. Oxid Med Cell Longev
. 2015
;2015
:579675
.
[PubMed]
1942-090017.
Denda
M
, Fuziwara
S
. Visible radiation affects epidermal permeability barrier recovery: selective effects of red and blue light
. J Invest Dermatol
. 2008
May
;128
(5
):1335
–6
.
[PubMed]
0022-202X18.
Duteil
L
, Cardot-Leccia
N
, Queille-Roussel
C
, Maubert
Y
, Harmelin
Y
, Boukari
F
, et al Differences in visible light-induced pigmentation according to wavelengths: a clinical and histological study in comparison with UVB exposure
. Pigment Cell Melanoma Res
. 2014
Sep
;27
(5
):822
–6
.
[PubMed]
1755-147119.
Souza
C
, Maia Campos
P
, Schanzer
S
, Albrecht
S
, Lohan
SB
, Lademann
J
, et al Radical-scavenging activity of a sunscreen enriched by antioxidants providing protection in the whole solar spectral range
. Skin Pharmacol Physiol
. 2017
;30
(2
):81
–9
.
[PubMed]
1660-552720.
Quistorf
JC
, Kockott
D
, Garbe
B
, Heinrich
U
, Tronnier
H
, Braun
N
. Development of an in vitro test procedure to determine the direct infrared a protection of sunscreens and non-cosmetic samples
. Skin Pharmacol Physiol
. 2017
;30
(4
):171
–9
.
[PubMed]
1660-552721.
Heinrich
U
, Tronnier
H
, Kockott
D
, Kuckuk
R
, Heise
HM
. Comparison of sun protection factors determined by an in vivo and different in vitro methodologies: a study with 58 different commercially available sunscreen products
. Int J Cosmet Sci
. 2004
Apr
;26
(2
):79
–89
.
[PubMed]
0142-546322.
Din en iso 24443:2012 determination of sunscreen uva photoprotetion in vitro. Berlin,
2013
,23.
Rozman
V
, zur Lage
J
, Moschner
A
, Kielbassa
A
, Lefort
M
, Pflucker
F
. Advanced light protection with titanium dioxide
. SOFW Journal
. 2017
;143
:20
–4
.24.
Schalka
S
. A. AF, Monteiro Agelune C, V. dMCP: Sunscreen protection against visible light: A new proposal for evaluation
. Surgical And Cosmetic Dermatology
. 2012
;3
:45
–52
.25.
Zastrow
L
, Groth
N
, Klein
F
, Kockott
D
, Lademann
J
, Renneberg
R
, et al The missing link—light-induced (280-1,600 nm) free radical formation in human skin
. Skin Pharmacol Physiol
. 2009
;22
(1
):31
–44
.
[PubMed]
1660-552726.
Zastrow
L
, Lademann
J
. Light - instead of uv protection: new requirements for skin cancer prevention
. Anticancer Res
. 2016
Mar
;36
(3
):1389
–93
.
[PubMed]
1791-753027.
Grether-Beck
S
, Marini
A
, Jaenicke
T
, Krutmann
J
. Effective photoprotection of human skin against infrared A radiation by topically applied antioxidants: results from a vehicle controlled, double-blind, randomized study
. Photochem Photobiol
. 2015
Jan-Feb
;91
(1
):248
–50
.
[PubMed]
0031-865528.
Meinke
MC
, Syring
F
, Schanzer
S
, Haag
SF
, Graf
R
, Loch
M
, et al Radical protection by differently composed creams in the UV/VIS and IR spectral ranges
. Photochem Photobiol
. 2013
Sep-Oct
;89
(5
):1079
–84
.
[PubMed]
0031-865529.
Meinke
MC
, Haag
SF
, Schanzer
S
, Groth
N
, Gersonde
I
, Lademann
J
. Radical protection by sunscreens in the infrared spectral range
. Photochem Photobiol
. 2011
Mar-Apr
;87
(2
):452
–6
.
[PubMed]
0031-865530.
Heinrich
U
, Moore
CE
, De Spirt
S
, Tronnier
H
, Stahl
W
. Green tea polyphenols provide photoprotection, increase microcirculation, and modulate skin properties of women
. J Nutr
. 2011
Jun
;141
(6
):1202
–8
.
[PubMed]
0022-316631.
Neukam
K
, Stahl
W
, Tronnier
H
, Sies
H
, Heinrich
U
. Consumption of flavanol-rich cocoa acutely increases microcirculation in human skin
. Eur J Nutr
. 2007
Feb
;46
(1
):53
–6
.
[PubMed]
1436-620732.
Stahl
W
, Heinrich
U
, Jungmann
H
, Sies
H
, Tronnier
H
. Carotenoids and carotenoids plus vitamin E protect against ultraviolet light-induced erythema in humans
. Am J Clin Nutr
. 2000
Mar
;71
(3
):795
–8
.
[PubMed]
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