Sunscreens are a key pillar of the multimodal protection strategy against short- and long-term impacts of intermittent and continuous UV exposure. Hitherto, an unanswered part of current scientific discourse is the question whether a cosmetic pretreatment has an impact on distribution and adhesiveness of sunscreens on the skin and therefore affects UV protection. In order to evaluate the homogeneity of sunscreen filter distribution, water resistance as a parameter of adhesiveness and effective UV protection of sunscreens after a pretreatment with cream or lotion was investigated in 18 volunteers who were examined before and after swimming, using the established combination of the tape stripping procedure and UV/VIS spectroscopy. It was shown that a cosmetic skin pretreatment affects neither filter homogeneity nor effective UV protection prior to water contact. However, compared to nonpretreated skin, a considerable loss of water resistance is caused. Therefore, using a cream or lotion before application of sunscreens is not to be recommended.

Genuis SJ: Keeping your sunny side up. How sunlight affects health and well-being. Can Fam Physician 2006;52:422-423, 429-431.
Lambert GW, Reid C, Kaye DM, Jennings GL, Esler MD: Effect of sunlight and season on serotonin turnover in the brain. Lancet 2002;360:1840-1842.
World Health Organization: IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Lyon, IARC, 1992, vol 55: Solar and ultraviolet radiation, pp 1-9.
Burke KE: Photoaging: the role of oxidative stress. G Ital Dermatol Venereol 2010;145:445-459.
Coelho Palermo Cunha G, van Ravenzwaay B, Tennekes HA, Mellert W, Schulte S, Burkhardt S: Effects of an ultraviolet B radiation absorber on photocarcinogenesis in hairless albino mice. Skin Pharmacol Physiol 2009;22:166-176.
Hanneman KK, Cooper KD, Baron ED: Ultraviolet immunosuppression: mechanisms and consequences. Dermatol Clin 2006;24:19-25.
Zastrow L, Groth N, Klein F, Kockott D, Lademann J, Renneberg R, Ferrero L: The missing link - light-induced (280-1,600 nm) free radical formation in human skin. Skin Pharmacol Physiol 2009;22:31-44.
Bimczok R, Gers-Barlag H, Mundt C, Klette E, Bielfeldt S, Rudolph T, Pflucker F, Heinrich U, Tronnier H, Johncock W, Klebon B, Westenfelder H, Flosser-Muller H, Jenni K, Kockott D, Lademann J, Herzog B, Rohr M: Influence of applied quantity of sunscreen products on the sun protection factor - a multicenter study organized by the DGK task force sun protection. Skin Pharmacol Physiol 2007;20:57-64.
Diffey BL: Sunscreens and UVA protection: a major issue of minor importance. Photochem Photobiol 2001;74:61-63.
Faurschou A, Wulf HC: The relation between sun protection factor and amount of suncreen applied in vivo. Br J Dermatol 2007;156:716-719.
Lademann J, Rudolph A, Jacobi U, Weigmann HJ, Schaefer H, Sterry W, Meinke M: Influence of nonhomogeneous distribution of topically applied UV filters on sun protection factors. J Biomed Opt 2004;9:1358-1362.
Teichmann A, Pissavini M, Ferrero L, Dehais A, Zastrow L, Richter H, Lademann J: Investigation of the homogeneity of the distribution of sunscreen formulations on the human skin: characterization and comparison of two different methods. J Biomed Opt 2006;11:064005.
Weigmann HJ, Jacobi U, Antoniou C, Tsikrikas GN, Wendel V, Rapp C, Gers-Barlag H, Sterry W, Lademann J: Determination of penetration profiles of topically applied substances by means of tape stripping and optical spectroscopy: UV filter substance in sunscreens. J Biomed Opt 2005;10:014009.
Beyer DM, Faurschou A, Philipsen PA, Haedersdal M, Wulf HC: Sun protection factor persistence on human skin during a day without physical activity or ultraviolet exposure. Photodermatol Photoimmunol Photomed 2010;26:22-27.
Bodekaer M, Faurschou A, Philipsen PA, Wulf HC: Sun protection factor persistence during a day with physical activity and bathing. Photodermatol Photoimmunol Photomed 2008;24:296-300.
COLIPA: Empfehlung Nr 16: Angabe der Wasserfestigkeit von Sonnenschutzmitteln. Frankfurt, IKW, 2006, p 2.
Rohr M, Rieger I, Jain A, Schrader A: Influence of repetitive UVA stimulation on skin protection capacity and antioxidant efficacy. Skin Pharmacol Physiol 2011;24:300-304.
Cambon M, Issachar N, Castelli D, Robert C: An in vivo method to assess the photostability of UV filters in a sunscreen. J Cosmet Sci 2001;52:1-11.
Jacobi U, Schanzer S, Weigmann HJ, Patzelt A, Vergou T, Sterry W, Lademann J: Pathways of lateral spreading. Skin Pharmacol Physiol 2011;24:231-237.
Stokes RP, Diffey BL: A novel ex vivo technique to assess the sand/rub resistance of sunscreen products. Int J Cosmet Sci 2000;22:329-334.
Stokes RP, Diffey BL, Dawson LC, Barton SP: A novel in vitro technique for measuring the water resistance of sunscreens. Int J Cosmet Sci 1998;20:235-240.
Weigmann HJ, Schanzer S, Teichmann A, Durat F, Antoniou C, Schaefer H, Sterry W, Lademann J: Ex-vivo spectroscopic quantification of sunscreen efficacy: proposal of a universal sun protection factor. J Biomed Opt 2007;12:044013.
Fitzpatrick TB: The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol 1988;124:869-871.
Gebauer V, Weigmann HJ, Schanzer S, Meinke MC, Vergou T, Sterry W, Lademann J: Influence of skin aging effects on the skin surface profile and the correlated distribution of topically applied sunscreens. J Biophoton 2012;5:274-282.
COLIPA: International Sun Protection Factor (SPF) Test Method. Brussels, Cosmetics Europe, 2006.
Lademann J, Jacobi U, Surber C, Weigmann HJ, Fluhr JW: The tape stripping procedure - evaluation of some critical parameters. Eur J Pharm Biopharm 2009;72:317-323.
Weigmann H, Lademann J, Meffert H, Schaefer H, Sterry W: Determination of the horny layer profile by tape stripping in combination with optical spectroscopy in the visible range as a prerequisite to quantify percutaneous absorption. Skin Pharmacol Appl Skin Physiol 1999;12:34-45.
Ferrero L, Pissavini M, Marguerie S, Zastrow L: Efficiency of a continuous height distribution model of sunscreen film geometry to predict a realistic sun protection factor. J Cosmet Sci 2003;54:463-481.
Schulz J, Hohenberg H, Pflucker F, Gartner E, Will T, Pfeiffer S, Wepf R, Wendel V, Gers-Barlag H, Wittern KP: Distribution of sunscreens on skin. Adv Drug Deliv Rev 2002;54(suppl 1):S157-S163.
Schaefer H, Redelmeier TE: Skin Barrier: Principles of Percutaneous Absorption. Basel, Karger, 1996.
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