.... As of this article’s publication, the only US Food and Drug Administration (FDA)-approved uses of FUS for movement disorders are thalamotomy for essential tremor (ET) and tremor-dominant Parkinson’s Disease (PD), and pallidotomy for other cardinal symptoms of PD. We present a state-of-the-art review on all non-FDA...

... of choice for tremor disorders, including tremor-dominant PD not suitable for DBS in the subthalamic nucleus (STN). In the last decade, several studies have shown promising results on tremor from DBS in the posterior subthalamic area (PSA), including the caudal zona incerta (cZi) located posteromedial...

...Rose M. Caston; Justin M. Campbell; Shervin Rahimpour; Paolo Moretti; Matthew D. Alexander; John D. Rolston Introduction: Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy is an incision-less ablative technique used to treat medically refractory tremor. Although intracerebral...

.... 2023 Deep brain stimulation Neuromodulation Direct targeting Parkinson disease Epilepsy Tremor Deep brain stimulation (DBS) is the most common form of surgical neuromodulation and is effective in treating numerous neurological conditions, such as essential tremor, Parkinson’s disease...

...Daniel Y. Zhang; John J. Pearce; Jacob Mazza; Edgar Petrosyan; Alireza Borghei; Neepa Patel; Sepehr Sani Introduction: Magnetic resonance-guided focused ultrasound (MRgFUS) represents an incisionless treatment option for essential or parkinsonian tremor. The incisionless nature of this procedure...

...Sarah E. Blitz; Matthew Torre; Melissa M.J. Chua; Sarah L. Christie; Nathan J. McDannold; G. Rees Cosgrove Magnetic resonance-guided high-intensity focused ultrasound (MRgFUS) is a rapidly developing technique used for tremor relief in tremor-predominant Parkinson’s disease (PD) and essential...

...Constantin Tuleasca; Tatiana Witjas; Marc Levivier; Nadine Girard; Axelle Cretol; Nicolas Levy; Jean-Philippe Thiran; Eric Guedj; Dimitri Van de Ville; Jean Régis Essential tremor (ET) is the most common movement disorder. Deep brain stimulation is the current gold standard for drug-resistant...

...Rik W.J. Pauwels; D.L. Marinus Oterdoom; Gea Drost; Teus van Laar; J. Marc C. van Dijk Background: Thalamotomy is an endorsed treatment for medication-refractory tremor. It used to be the standard, but nowadays deep brain stimulation (DBS) has become the treatment option of choice. Nevertheless...

...Takashi Isobe; Hiromasa Sato; Tetsuya Goto; Takehiro Yako; Kunihiro Yoshida; Takao Hashimoto The beneficial effect of thalamic deep brain stimulation (DBS) on action tremor has been reported in a few cases of spinocerebellar ataxia (SCA); however, several factors should be taken into account...

... in prelemniscal radiation fibers (Raprl) related to the physiopathology of tremor evidenced by tractography. Case Report: We report a patient with predominant unilateral rest and postural tremor, diagnosed as PD based on 80% improvement induced by the administration of L-DOPA/carbidopa, subsequently complicated...

...Sudesh S. Raju; Ajay Niranjan; Edward A. Monaco III; John C. Flickinger; L. Dade Lunsford Objective: The purpose of this study was to retrospectively analyze the outcomes of stereotactic radiosurgery for patients suffering from medically refractory Parkinson disease (PD) tremor. Methods: We...

... tremor in Parkinson disease. Similarly, thalamic stimulation (ventral intermediate nucleus; VIM) has shown tremor control in Parkinson disease, essential, and intention tremors. Recently, stimulation of the posterior subthalamic area (PSA) has been associated with excellent tremor control. Thus...

...Lidia Cabañes-Martínez; Marta Del Álamo de Pedro; Gema de Blas Beorlegui; Ignacio Regidor Bailly-Bailliere Background: It has been described that many Charcot-Marie-Tooth syndrome type 2 patients are affected by a very disabling type of tremor syndrome, the pathophysiology of which remains unclear...

...Adolfo Ramirez-Zamora; Heather Smith; Vignessh Kumar; Julia Prusik; Sujoy Phookan; Julie G. Pilitsis Background: Although thalamic deep brain stimulation (DBS) has been established as an effective therapy for refractory tremor in Parkinson's disease and essential tremor, reports investigating...

...Pieter L. Kubben; Mark L. Kuijf; Linda P.C.M. Ackermans; Albert F.G. Leentjes; Yasin Temel Background: Evaluating the effect of treatment of tremor is mostly performed with clinical rating scales. Mobile applications facilitate a more rapid, objective, and quantitative evaluation of treatment...

... (PD). This report documents the incidence of changes in motor symptoms (especially tremor) in PD patients sedated with dexmedetomidine for deep brain stimulation or ablation procedures. Methods: We reviewed a retrospective cohort of 22 patients who underwent surgery for PD with dexmedetomidine...

...Suhan Senova; Damien Querlioz; Claire Thiriez; Pierre Jedynak; Béchir Jarraya; Stéphane Palfi Background/Aims: Evaluation of tremor constitutes a crucial step from the diagnosis to the initial treatment and follow-up of patients with essential tremor. The severity of tremor can be evaluated using...

... Infection Functional neurosurgery Parkinson’s disease Tremor Deep brain stimulation (DBS) is an FDA-approved elective surgical intervention for movement disorders such as essential tremor (ET), dystonia and Parkinson's disease (PD) that have become refractory to medication management. DBS is also...

..., and a nonvalidated patient telephone questionnaire to assess patients’ perception of tremor and functional ability after thalamotomy. Results: Six patients with essential tremor and 1 with tremor-predominant Parkinson’s disease met our inclusion criteria. Thalamotomies were undertaken for ineffective DBS due...

... the indications, outcome and complications in patients who had undergone both a lesioning (thalamotomy) and deep brain stimulation (DBS) procedure (bilateral or unilateral) for a tremor-predominant movement disorder performed by a single surgeon at one institution over a 15-year period. Methods: A retrospective...