...W. Winkelmüller; F.M. Nitsch Bilateral lesions in the substantia nigra were induced in rats trained in an instrumental learning program comparable with a fixed-interval schedule. General observations and examinations of rough motor behavior revealed rigidity, a decrease in spontaneous activity...

...Patrick J. Kelly Patients with parkinsonian tremor and rigidity and cerebellar intention tremor can be effectively treated with thalamic lesions provided that an accurate neurophysiologic method is employed to compensate for individual spatial variability of subcortical structures. The method...

.... These quantification techniques also have promise in evaluating treatment regimens for spasticity, rigidity, and other conditions with abnormal motor tone. 7 2 2007 © 1991 S. Karger AG, Basel 1991 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

...H. Narabayashi With a short description of the historical background, thalamotomy and posteroventral pallidotomy (PVP) are introduced as effective means to alleviate motor symptoms in Parkinson’s disease (PD). Rigidity and dopa-induced dyskinesia are improved and abolished by either of the two...

...H. Narabayashi Posteroventral pallidotomy (PVP) has been shown to alleviate motor symptoms in Parkinson''s disease (PD), e.g., rigidity, secondary akinesia due to existence of muscle rigidity and slight tremor, but not the marked tremor. For the latter, additional lesion of the ventral intermediate...

...Lauri V. Laitinen Recent laboratory experiments have produced increasing evidence that nigral-striatal dopamine deficiency causes an inhibitory hyperactivity in the medial globus pallidus (MGP), where it freezes the initiation of movement and thus causes bradykinesia, rigidity and tremor. Surgical...

...Francisco Velasco; Marcos Velasco; Héctor Rodriguez Cuevas; Juan Jurado; Juan Olvera; Fiacro Jiménez Ten patients with advanced Parkinson’s disease, presenting with tremor, rigidity and akinesia had autologous adrenal medullary transplantation taken from the left adrenal gland to the head...

...L.V. Laitinen; A.T. Bergenheim; M.I. Hariz Stereotactic ventroposterolateral pallidotomy in 46 parkinsonian patients resulted in a complete or almost complete and long-lasting relief of rigidity and hypokinesia in 91% of the patients. Good tremor effect was obtained in 80% of them. The L -dopa...