... to in the content or advertisements. 2024 Essential tremor Focused ultrasound Functional neurosurgery Movement disorder surgery Parkinson’s disease Thalamotomy Magnetic resonance-guided focused ultrasound (MRgFUS) thalamotomy has emerged as a promising noninvasive therapeutic modality...

...Jennifer A. Guidera; Sravani Kondapavulur; Doris D. Wang Introduction: Focused ultrasound (FUS) pallidotomy is a promising new therapy for Parkinson’s disease (PD). The efficacy, motor outcomes, and side effects of FUS pallidotomy compared to radiofrequency (RF) pallidotomy are unknown. Methods: We...

...Kenneth Ong; Franziska Schmidt; Kira Tosefsky; Muhammad Faran; Can Sarica; Christopher R. Honey; Fidel Vila-Rodriguez; Stefan Lang Introduction: Deep brain stimulation of the subthalamic nucleus is an effective therapy for the motor symptoms of Parkinson’s disease (PD). Typically, stimulation...

...) for Parkinson’s disease (PD). Methods: We conducted a retrospective chart review of all PD patients that received STN DBS in our DBS center between 1998 and 2023. Outcomes were complications resulting in neurological deficit or additional surgery. Potential risk factors (number of microelectrode recording tracks...

...Julia M. Mueller; Lucinda T. Chiu; Fiona Lynn; Rachel G. Lewis; Shama Patel; Matthew Wodziak; Neepa Patel; Sepehr Sani Introduction: Magnetic resonance-guided focused ultrasound (MRgFUS) is an effective treatment option for essential tremor (ET) and tremor dominant Parkinson’s disease (TDPD), which...

...Rasmus Stenmark Persson; Anders Fytagoridis; Maxim Ryzhkov; Marwan Hariz; Patric Blomstedt Introduction: Deep brain stimulation (DBS) is an established treatment for Parkinson’s disease (PD) and other movement disorders. The ventral intermediate nucleus of the thalamus is considered as the target...

...Kostiantyn Kostiuk Introduction: Parkinson’s disease (PD) is one of the most common neurodegenerative progressive disorders. Despite the dominance of neurostimulation technology, stereotactic lesioning operations play a significant role in the treatment of PD. The aim of the study was to evaluate...

...Marwan Hariz; Laura Cif; Patric Blomstedt Background: The advent of deep brain stimulation (DBS) of the subthalamic nucleus (STN) for Parkinson’s disease 30 years ago has ushered a global breakthrough of DBS as a universal method for therapy and research in wide areas of neurology and psychiatry...

..., clinical use cases, and surgical technique are described in a cohort of 12 patients with epilepsy, essential tremor, Parkinson’s disease, mixed tremor, and Tourette’s syndrome with comorbid obsessive-compulsive disorder between July 2021 and July 2022. Results: This system is a rechargeable 32-channel, 4...

...; Suneil K. Kalia; Robert Chen; Alfonso A. Fasano; Andres M. Lozano Background: Spinal cord stimulation (SCS) has been investigated as a potential therapeutic option for managing refractory symptoms in patients with Parkinson’s disease (PD). Objective: This systematic review and meta-analysis aimed...

... imaging (MRI) of the basal ganglia during stereotactic neurosurgery. Methods: This pilot study was conducted in 4 patients with Parkinson’s disease (PD) who underwent MRI-guided deep brain stimulation of the globus pallidus internus (GPi). CSF was obtained via lumbar puncture after general anesthesia...

...Sarah E. Blitz; Matthew Torre; Melissa M.J. Chua; Sarah L. Christie; Nathan J. McDannold; G. Rees Cosgrove Magnetic resonance-guided high-intensity focused ultrasound (MRgFUS) is a rapidly developing technique used for tremor relief in tremor-predominant Parkinson’s disease (PD) and essential...

...Alexandra Boogers; Tine Van Bogaert; Jana Peeters; Ugur Kilic; Stefan Sunaert; Wim Vandenberghe; Myles Mc Laughlin; Philippe De Vloo; Bart Nuttin Deep brain stimulation is an established treatment option for both essential tremor (ET) and Parkinson’s disease (PD), although typically targeting...

...Marwan Hariz; Andrew J. Lees; Yulia Blomstedt; Patric Blomstedt Background: Serendipity and observations have a noble tradition in medicine, including neurology, and are responsible for many medical treatments (carbamazepine for tic douloureux, amantadine for Parkinson’s disease, gabapentin...

.... Lozano; Rob M.A. De Bie; Yasin Temel; Marcus L.F. Janssen Background: Subthalamic nucleus deep brain stimulation (STN DBS) is an established therapy for Parkinson’s disease (PD) patients suffering from motor response fluctuations despite optimal medical treatment, or severe dopaminergic side effects...

... Movement disorders Movement disorder surgery Parkinson’s disease Surgical wound infection Deep brain stimulation (DBS) is a safe and effective surgical option for management of a variety of disorders, particularly movement disorders including Parkinson’s disease and essential tremor. While...

... stimulation (DBS) for Parkinson’s disease (PD) is being performed more frequently; however, motor outcomes and safety of asleep DBS have never been assessed in a prospective randomized trial. Methods: We conducted a prospective, randomized, noncomparative trial to assess the motor outcomes of asleep DBS...

... objective overall motor and gait subsection scores as well as patient-reported outcomes were recorded for 6 PPN-DBS-treated patients, 3 with Parkinson’s disease (PD), and 3 with progressive supranuclear palsy (PSP). Electrodes were implanted unilaterally in the first 3 patients and bilaterally in the latter...

... an evidence-based programming algorithm for patients with Parkinson’s disease undergoing subthalamic nucleus deep brain stimulation with directional leads. Methods: Fourteen consecutive patients were randomized to programming with either early or delayed (i.e., starting with a “ring mode”) steered stimulation...

...Alexis de Roquemaurel; Thomas Wirth; Nirosen Vijiaratnam; Francisca Ferreira; Ludvic Zrinzo; Harith Akram; Thomas Foltynie; Patricia Limousin Introduction: While deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been extensively used for more than 20 years in Parkinson’s disease (PD...