...). The pooled effect size of five studies on back and leg pain VAS scores was calculated as 4.38 (95% CI: 2.67; 6.09, p < 0.001), equivalent to a 59% reduction. Conclusions: Our analysis suggests that SCS may provide significant motor and pain benefits for patients with PD, although the results should...

... radiosurgery (GKS) with random use of a frame or a mask for fixation were included patients older than 18, with <5 brain metastases (at the exclusion of brainstem and optic pathway’s locations) and no earlier history of radiotherapy. The primary outcome measure was the pain scale assessment (PSA...

.... Objective: Using the G102RS device (PINS Medical, China), we investigated the LFP changes in response to mechanical pain stimulation to further elucidate the representation of pain sensation in the basal ganglia. Methods: LFPs from 2 patients who had undergone bilateral STN-DBS were wirelessly recorded...

...Yijie Lai; Yixin Pan; Linbin Wang; Chencheng Zhang; Bomin Sun; Dianyou Li Spinal cord stimulation (SCS) is receiving increasing interests for treating pain and gait disorders in patients with Parkinson’s disease (PD). In an SCS study, it is hard to apply a double-blind approach, especially at low...

... and brain injury. Objectives: The objective of this study was to assess the effectiveness of the ITB in patients with inherited ataxia suffering from severe painful spasms and/or spasticity. Method: A total of 5 patients with spinocerebellar ataxia 3 or 7 or Friedreich’s ataxia were included...

..., instructions or products referred to in the content or advertisements. Balloon compression Foramen ovale Functional neurosurgery Image fusion Pain Trigeminal neuralgia Rhizotomy Magnetic resonance imaging Percutaneous balloon compression is both a clinically effective and a cost-effective...

...Ido Strauss; Assaf Berger; Michal Arad; Uri Hochberg; Rotem Tellem Background: Pain is often one of the most debilitating symptoms in patients with advanced oncological disease. Patients with localized pain due to malignancy refractory to medical treatment can benefit from selective percutaneous...

...Byung-Chul Son; Jin-Gyu Choi; Sang-Woo Ha; Deog-Ryeong Kim Aims: To address the feasibility and importance of intraoperative neurophysiological monitoring (IONM) in dorsal root entry zone (DREZ) lesioning for brachial plexus avulsion pain. Methods: Muscle motor evoked potential (mMEP...

...Won Kim; Srinivas Chivukula; Jason Hauptman; Nader Pouratian Background/Aims: Thalamic deep brain stimulation (DBS) for the treatment of medically refractory pain has largely been abandoned on account of its inconsistent and oftentimes poor efficacy. Our aim here was to use diffusion tensor imaging...

.... A total of 122 patients (93.8%) became pain free (median delay = 15 days) after the radiosurgery procedure (Barrow Neurological Institute, BNI class I-IIIa). The probability of remaining pain free without medication at 3, 5, 7 and 10 years was 77.9, 73.8, 68 and 51.5%, respectively. Fifty-six patients...

... with an anterograde C 4 /C 5 insertion. Repositioning of leads based on significantly asymmetrical collision testing of SSEP and thresholds of CMAP in bilateral extremities was needed in 6 and 8 patients, respectively. In 22 patients, paresthesia coverage of the painful area was consistently located in the painful...

... pain Pain Pain pathways Psychosurgery Stimulation Thalamic stimulation Thalamus We read with great interest the publication by Son et al. [ 1 ] entitled ‘Simultaneous trial of deep brain and motor cortex stimulation in chronic intractable neuropathic pain', published in Stereotactic...

...Heather Smith; Lucy Gee; Vignessh Kumar; Adolfo Ramirez-Zamora; Jennifer Durphy; Era Hanspal; Anne Barba; Eric Molho; Damian Shin; Julie G. Pilitsis Background: Up to 60% of Parkinson's disease (PD) patients suffer from low back pain (LBP) during the course of their disease. How LBP affects daily...

... involving primarily the right cingulate gyrus. An attempt to explore the underlying role of the cingulate cortex in pain modulation by appraising the current literature is presented. This report suggests that the cingulate gyri could be a potential target for neuromodulation in patients with medically...

... brain stimulation (DBS) in chronic pain. Aims: The study is an investigation of somatotopic representation in PAVG and assessment for a somatosensory homunculus. Methods: Five human subjects were investigated using electrical somatosensory stimulation and deep brain macroelectrode recording. DBS were...

...F.L. Jenkner; F. Schuhfried A search has been made for an optimal wave form for transcutaneous nerve stimulation for pain. The effect of electrical stimulation of sympathetic nerves was studied as a model because (1) this system has small diameter axons, as do nociceptive fibers, and (2) alteration...

...John Gorecki; Teruyasu Hirayama; Jonathan O. Dostrovsky; Ronald R. Tasker; Fredrick A. Lenz Thalamic exploration was carried out in 39 patients with central or deafferentation pain. Several patients were explored more than once or bilaterally; therefore, 52 explorations were carried out. In 16...

...Teruyasu Hirayama; Jonathan O. Dostrovsky; John Gorecki; Ronald R. Tasker; Fredrick A. Lenz We have performed a single-unit analysis of the spontaneous activity of cells in 9 patients with central and deafferentation pain and 4 patients without pain. These studies have concentrated on the analysis...

...Alexandros G. Brotis; Eftychia Z. Kapsalaki; Konstantinos Paterakis; Joseph R. Smith; Kostas N. Fountas Stereotactic cingulotomy constitutes a psychosurgical procedure nowadays advocated in the treatment of medically intractable obsessive-compulsive disorder, chronic pain and drug addiction. From...

... to preoperative pain dermatomes indicated by the patient. The ability to produce paresthesias as well as the voltage required to produce paresthesias under anesthesia were recorded. Patient demographics, amount and concentration of epidural drugs, use of local anesthetic or sedatives, and any complications were...