...Trevor Hurwitz; Geoffrey Ching; Nicholas Mark Bogod; Christopher R. Honey Introduction: Ablative surgery is an intervention of last resort for treatment-resistant obsessive-compulsive disorder (TROCD). Our center has been using bilateral anterior capsulotomy (BAC) for the past 20 years for patients...

...Hongyang Li; Siyu Yuan; Lulin Dai; Hui Huang; Zhengyu Lin; Shikun Zhan; Jie Luo; Wei Liu; Bomin Sun Introduction: A bilateral anterior capsulotomy effectively treats refractory obsessive-compulsive disorder (OCD). We investigated the geometry of lesions and disruption of white matter pathways...

...(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Deep brain stimulation Humanitarian device exemption Obsessive-compulsive disorder Dystonia Payer policy...

...Jürgen Germann; Alexandre Boutet; Gavin J.B. Elias; Flavia Venetucci Gouveia; Aaron Loh; Peter Giacobbe; Venkat Bhat; Walter Kucharczyk; Andres M. Lozano Background: Obsessive-compulsive disorder (OCD) is a debilitating disease with a lifetime prevalence of 2–3%. Neuromodulatory treatments have...

... consequences of the Humanitarian Device Exemption (HDE) approval status of DBS for obsessive-compulsive disorder (OCD). Retrospective analyses akin to failure modes and effects analysis in engineering may clarify unexpected results in the DBS depression trials. Recent research suggests that subject selection...

... disorders such as obsessive-compulsive disorder (OCD). In refractory cases deep brain stimulation (DBS) is a valid treatment option. This paper describes the case of a 15-year-old adolescent with an extremely refractory GTS with associated OCD. The patient developed catatonia associated with OCD, which...

.... Conclusions: The optimum outcome following BAC surgery in this cohort was associated with interruption of vmPFC pathways and the relative preservation of DLPFC pathways. Capsulotomy Anterior limb of the internal capsule Tractography Depression Obsessive-compulsive disorder Limbic system Frontal lobes...

...Feilong Gong; Bin Li; Shizhen Zhang; Yi Wang; Yuan Gao; Yangyang Xu; Xin Wang; Botao Xiong; Denghui Li; Rong Wen; Zhen Qin; Wei Wang Objective: Anterior capsulotomy (AC) is sometimes used as a life-saving treatment for patients with treatment-refractory obsessive-compulsive disorder (Tr-OCD). Most...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Body mass index Obsessive-compulsive disorder Weight Deep brain...

... Obsessive-compulsive disorder Erethism or intermittent explosive disease (IED) is a psychiatric disorder characterized by episodes of impulsive aggression usually associated with mental impairment and acquired or congenital brain lesions [ 1,2,3,4,5,6,7,8,9,10 ]. Different lesional stereotactic...

... Obsessive-compulsive disorder Psychosurgery The nucleus accumbens (NAc) is a major component of the ventral striatum and has long been thought to be a key structure involved in mediating motivational and emotional processes, the limbic-motor interface, and the effects of certain psychoactive drugs...

... will ultimately be an important therapeutic modality. Deep brain stimulation Depression Neuromodulation Surgical treatment Tourette syndrome Obsessive-compulsive disorder Psychosurgery © 2012 S. Karger AG, Basel Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part...

... capsule in 3 patients with obsessive-compulsive disorder (OCD) using blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) under intraoperative conditions. Methods: After placement of the electrode in the right ACC, the patients underwent an MR scan inside the operating...

...Raj Nangunoori; Nestor D. Tomycz; Matthew Quigley; Michael Y. Oh; Donald M. Whiting Background: Deep brain stimulation (DBS) has emerged in recent years as a novel therapy in the treatment of refractory psychiatric disease, including major depressive disorder (MDD), obsessive-compulsive disorder...

...Juan A. Barcia; Laura Reyes; Rocío Arza; Javier Saceda; Josué Avecillas; Rosa Yáñez; Julia García-Albea; Tomás Ortiz; Maria-Inés López-Ibor; Juan-José López-Ibor Background: Deep brain stimulation for obsessive-compulsive disorder (OCD) has targeted several subcortical nuclei, including...

...Q.J. Zhang; W.H. Wang; X.P. Wei Objective: To investigate the long-term efficacy and adverse effects of stereotactic bilateral anterior cingulotomy (BACI) and bilateral anterior capsulotomy (BACA) as a treatment for refractory obsessive-compulsive disorder (OCD) patients. Methods: Seven patients...

...F. Gouvea; A. Lopes; B. Greenberg; M. Canteras; A. Taub; M. Mathis; E. Miguel This case regards a 34-year-old woman with severe and refractory obsessive-compulsive disorder, who was enrolled in a double-blind, randomized controlled trial of radiosurgery. She was at first submitted to a sham...

...Alexandros G. Brotis; Eftychia Z. Kapsalaki; Konstantinos Paterakis; Joseph R. Smith; Kostas N. Fountas Stereotactic cingulotomy constitutes a psychosurgical procedure nowadays advocated in the treatment of medically intractable obsessive-compulsive disorder, chronic pain and drug addiction. From...

...Felipe E. Allendes; Andres M. Lozano; William D. Hutchison Aberrant synaptic plasticity in corticostriatal circuits may be an underlying mechanism of anxiety disorders such as obsessive-compulsive disorder (OCD). We explored the effect of anterior capsulotomy in an OCD patient on long-term...

... depression (n = 4) and obsessive-compulsive disorder (n = 1) underwent stereotactic bilateral anterior capsulotomy. All patients had postoperative MRI at 2 months and at 1–4 years after surgery. An additional patient who had a pure motor deficit following a spontaneous basal ganglia hemorrhagic stroke...