... imaging (MRI) of the basal ganglia during stereotactic neurosurgery. Methods: This pilot study was conducted in 4 patients with Parkinson’s disease (PD) who underwent MRI-guided deep brain stimulation of the globus pallidus internus (GPi). CSF was obtained via lumbar puncture after general anesthesia...

... to 50 age-matched control patients. Results: There was a 10-fold preponderance of percentaged SA within the globus pallidus (GP) in dystonia patients. The greatest disparity was in young patients <25 years. Also, total BG volume differences were observed with larger GP and markedly smaller putamen...

...Rodrigo Mercado-Pimentel; Fabian Piedimonte; Federico Micheli; Verónica Montilla-Uzcátegui; Nicolás Barbosa; Carolina Ramírez-Gómez; Carlos Zúñiga-Ramírez Surgical approaches of internal globus pallidus (GPi) and ventral intermediate thalamic nucleus (Vim) have been used to treat different movement...

...Assel Saryyeva; Hans Holger Capelle; Thomas Mehari Kinfe; Christoph Schrader; Joachim K. Krauss Introduction: Deep brain stimulation (DBS) of the globus pallidus internus has become an accepted treatment for severe isolated idiopathic and inherited dystonia. Patients who had other forms of surgery...

... brain stimulation Globus pallidus X-linked dystonia parkinsonism (XDP) is a neurodegenerative disorder first described by Lee et al. [ 1 ] in 1976. It has been indexed as DYT3 dystonia and is also known worldwide as “Lubag dystonia,” a term coined by Fahn [ 2 ] and Wilhelmsen et al. [ 3...

..., it is generally accepted that anesthesia affects MER. Due to a potential role of local field potentials (LFPs) in DBS functional mapping, we characterized the effect of propofol on globus pallidus interna (GPi) and externa (GPe) LFPs in Parkinson disease (PD) patients. Methods: We collected LFPs in 12 awake...

...Raymond J. Cook; Lyndsey Jones; George Fracchia; Nathan Anderson; Jenny Miu; Linton J. Meagher; Peter A. Silburn; Paul Silberstein Background: Deep brain stimulation (DBS) at the subthalamic nucleus (STN) or globus pallidus internus (GPi) can effectively treat the motor symptoms of Parkinson's...

...Christopher Tolleson; Srivatsan Pallavaram; Chen Li; John Fang; Fenna Phibbs; Peter Konrad; Peter Hedera; Pierre-François D''Haese; Benoit M. Dawant; Thomas L. Davis Background: Deep brain stimulation (DBS) of the globus pallidus internus is established as efficacious for dystonia, yet the optimal...

... for DBS in psychiatric disorders using the best evidence available, we reviewed the DBS psychosurgery literature and subjected it to a pooled analysis through a sieve focused on standardized outcome studies. Deep brain stimulation Depression Functional neurosurgery Globus pallidus...

... treated with unilateral globus pallidus interna DBS. Methods: Case series describing characteristics and outcomes based on the Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) scores before and after DBS at 3, 6 and at least 12 months. Results: All patients reported subjective improvements after surgery...

...Jared Fridley; Gareth Adams; Ping Sun; Michelle York; Farah Atassi; Eugene Lai; Richard Simpson; Ashwin Viswanathan; Daniel Yoshor Background: Deep brain stimulation (DBS) of either the globus pallidus interna (GPi) or subthalamic nucleus (STN) is similarly effective for treating somatomotor...

... describe an unusual complication associated with DBS of the globus pallidus internus (GPi). The patient was a 34-year-old man with a 5-year history of progressive cervical dystonia that was unresponsive to medical treatment. He underwent bilateral DBS of the posteroventral GPi. After test stimulation...

... techniques Corpus striatum Globus pallidus Amygdala Stereotactic surgery Abstract. Our review has shown that recent studies with the new anterograde and retrograde axon transport methods have confirmed and extended our knowl­ edge of the projection of the basal ganglia and clarified their sites...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Basal ganglia Substantia nigra Neuroanatomical techniques Corpus striatum Globus pallidus Amygdala Stereotactic surgery Mehler 276 course...

... was performed after suffocation. The jaw-opening dystonia disappeared immediately following pallidotomy; the tracheotomy was closed, and he regained eating and speech ability. Analysis of the neuronal firing of the globus pallidus revealed low neuronal firing rates in the internal pallidum (GPi...

...Brian D. Berman; Philip A. Starr; William J. Marks, Jr.; Jill L. Ostrem Background: Deep brain stimulation (DBS) of the globus pallidus internus (GPi) is an effective and well-tolerated treatment for idiopathic generalized dystonia. More recently, it has been applied as a treatment for focal...

... – were used. Concentric bipolar electrodes were stereotaxically implanted in the unilateral subthalamic nucleus (STN), stimulated by high frequencies of 130 and 260 Hz in each group. The microdialysis probes were unilaterally lowered into the globus pallidus (GP) and the substantia nigra pars reticulata...

...J. Feger; J.M. Deniau; C. Hammond-Le Guyader; C. Ohye Many data suggest that the basal ganglia exerts an indirect influence onto the motor cortex through the thalamus which receives pallidal and nigral efferences. According to the anatomical data, the internal segment of globus pallidus projects...

...Sanford J. Larson; Anthony Sances Jr.; Nicholas Wetzel The brains of 5 patients who died at varying intervals following stereotactic pallidotomy or thalamotomy were examined using the Marchi stain for degenerating myelin. In 2 patients, the lesion was directed at the globus pallidus; in 2...

... patient with a poststroke Holmes’ tremor, we implanted DBS electrodes in unilateral V.im., V.o.a., and the globus pallidus internus (Gpi); this patient had moderate tremor reduction with Gpi stimulation alone; neither V.im. nor V.o.a. stimulation provided additional benefit. Conclusion: In one patient...