More than 290 cases of cerebral arteriovenous malformation have been treated at our hospital by Gamma Knife radiosurgery since May 1991, of which 99 were followed with angiography for 1 year or more. The results from adult and pediatric age groups were compared. There were 70 adults and 23 children. Previous hemorrhage had occurred in 73.7% of the adults and 91.3% of the children. The mean volume of the nidus was similar in both groups: 4.2 cm3 in adults and 4.8 cm3 in children. In both groups approximately 70% of the cases fell into Spetzler and Martin grade III. The mean margin dose was 20.0 Gy in the adults and 20.5 Gy in the children. Complete nidus occlusion at 1 year occurred in 45% of the adults and 74% of the children. The rates at 2 years were 81 and 94%, respectively. Complications occurred only in adults and consisted of 2 rebleeds, 1 radiation edema and 1 radiation necrosis. Gamma Knife radiosurgery is considered to be safer and have a higher success rate in children than in adults.

Keywords:
Gamma Knife, Radiosurgery, Arteriovenous malformation, Children, Pediatric
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© 1996 S. Karger AG, Basel
1997
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