...Aditya K. Gupta; Tong Wang; Anh N. Tran Introduction: Onychomycosis is a complex nail disease that is commonly seen in daily practice. Methods: Electronic health records of clinically diagnosed onychomycosis patients were extracted using DataDerm – a dermatology data registry hosted by the American...

...Aditya K. Gupta; Daniel Taylor; Shruthi Polla Ravi; Tong Wang; Mesbah Talukder Introduction: Oral antifungals were the earliest treatments to receive approval for the management of onychomycosis and have a long-standing record to support their efficacy. Topical antifungals and device-based...

...Laura Gnesotto; Giuseppe Emilio Cannata; Giacomina Pavan; Luigi Naldi; Andrea Sechi Introduction: Onychomycosis is the most common nail infection, predominantly caused by Trichophyton spp., and is divided into four main types. Confirmatory testing is crucial, but obtaining an adequate sample may...

...Zi-Ning Choo; Shari R. Lipner Introduction: Onychomycosis is common among adults with diabetes mellitus (DM). We used two-sample Mendelian randomization to estimate the causal effect of genetic risk for DM on onychomycosis and tinea skin infections in the All of Us Research Program. Methods...

... in recommending natural treatments for the following common nail disorders: nail brittleness, onychomycosis, periungual verrucae, paronychia, chloronychia, nail psoriasis, nail lichen planus, onychocryptosis, onycholysis, and congenital malalignment of the great toenail. One limitation is the scarcity of existing...

...Kelita A. Waterton; Shari R. Lipner Background: Onychomycosis is the most frequently diagnosed nail condition in clinical practice. With the growing popularity of TikTok and online health information-seeking behavior, it is imperative to understand onychomycosis-related content on this platform...

... running errands alone, bathing, and concentrating), psoriasis, onychomycosis, hallux malleus, hallux valgus, peripheral vascular disease, lower extremity ulcers, venous varices, and type II diabetes mellitus. Therefore, physicians should screen patients presenting with onychogryphosis for these conditions...

...Eeshaan Ranjan; Sandeep Arora; Ajay Shanker Sharma; Neha Sharma; Rajeshwari Dabas Introduction: Onychomycosis is a common nail disorders. Antifungal resistance, interactions, and side effects limit treatment options. Fractional CO 2 (FCO 2 ) laser along with topical antifungal is effective...

...Samantha Jo Albucker; Shari R. Lipner Introduction: Onychomycosis represents half of nail disorders seen in clinical practice. Despite its high prevalence, a bibliometric analysis has not been performed. We aimed to identify the top 100 highly cited onychomycosis publications over the last 50 years...

... presentation and antimicrobial immune responses involve the human leukocyte antigen (HLA) system. Onychomycosis is primarily caused by dermatophytes and affects around 5.5% of the population worldwide. Yet, only limited data exist on the associations between the HLA system and onychomycosis. Thus...

...Flávia Trevisan; John Verrinder Veasey; Betina Werner Introduction: The etiological agents of onychomycosis are dermatophyte fungi, nondermatophyte filamentous fungi (NDFF), and yeasts. Nail clippings are an accurate tool for diagnosing onychomycosis. The objective of this study was to correlate...

... by the participants through a questionnaire and from medical records. We performed direct cytological examinations and nail mycological cultures in participants with symptoms of onychomycosis. Results: The participants were predominantly male patients (91.2%), with a mean age of 41 (range 21–78) years, under...

...Rhiannon C. Miller; Shari R. Lipner Introduction: Oral antifungals are typically preferred over topicals for moderate to severe onychomycosis due to efficacy and shorter treatment courses. However, systemics are contraindicated or cautioned in patients with liver dysfunction and with some...

...Melissa A. Nickles; Meghan Pavelka; Julie E. Mervak Background: While the Internet remains a popular source of health information, YouTube may contain bias and incomplete information regarding common dermatological conditions. Objective: Our objective was to quantify onychomycosis treatment...

...Melissa A. Nickles; Peter A. Lio; Julie E. Mervak Introduction: Onychomycosis is notoriously difficult to treat. While oral antifungals are the most efficacious treatment for onychomycosis, they are contraindicated in certain patient populations, and patients may desire lower risk and accessible...

...Shari R. Lipner; Mahmoud Ghannoum; Molly A. Hinshaw; Phoebe Rich; Beth S. Ruben; Tracey C. Vlahovic; Richard K. Scher Onychomycosis is the most common nail condition seen in clinical practice, with significant impact on quality of life. Clinical examination alone is insufficient for accurate...

...Carlos Daniel Sánchez-Cárdenas; Diana Carolina Vega-Sánchez; Tania Rosalia González-Suárez; José Flores-Rivera; Roberto G. Arenas; Teresa Corona We report the first case of onychomycosis caused by Kloeckera apiculata in a woman with multiple sclerosis. Video-dermoscopic examination showed a spiked...

... if this condition is underdiagnosed and underreported. Onychomycosis is an important differential diagnosis of onychomatricoma, and sometimes, both these conditions may even coexist in the same nail. As the tumor grows, tissue microenvironment is more vulnerable to dermatophytes. Probably, the altered keratin...

...Nilton Di Chiacchio; Gustavo de Sá Menezes Carvalho; Nilton Gioia Di Chiacchio; Cristina Diniz Borges Figueira de Mello; John Verrinder Veasey Introduction: Onychomycosis is a frequent complaint in dermatological practice and corresponds to the most common nail disease. The treatment...

...Aditya K. Gupta; Maanasa Venkataraman; Emma M. Quinlan; Madhulika A. Gupta; Naveen Anbalagan; Rachel Lyons Introduction: Onychomycosis is a common, difficult-to-treat fungal nail infection. Clinical signs include nail discoloration and thickening, which patients often find embarrassing, causing...