.... Congenital hypotrichosis with juvenile macular dystrophy is one of the entities included in ED, which is associated with an alteration in the CDH3 gene encoding P-cadherin. Case Presentation: We describe a 6-year-old patient with history of atopic dermatitis, amblyopia, and reduced vision acuity. Physical...

...Azhar Ahmed; Azhar Alali; Osama Alsharif; Adnan Kaki Hypotrichosis with juvenile macular dystrophy is an autosomal recessive disorder due to a mutation in the CDH3 gene. As its name indicates, the disease classically presented with hypotrichosis and early visual impairment. We describe herein...

... been postulated to play a role in hair follicles, ultimately IGF-1 is known to be regulated by androgens. Accordingly, dermal papillary cells from balding scalp follicles were found to secrete significantly less IGF-1 than their counterparts from nonbalding scalp follicles. Herein, hypotrichosis...