Abstract
Introduction: Onychomatricoma is a benign tumor that originates from the nail matrix. The main clinical features reported include longitudinal thickening of the nail plate, splinter hemorrhages, and xanthonychia. Objective: The aims of the study were to describe epidemiological, clinical, and dermoscopy data of patients with dark skin phototypes (Fitzpatrick IV, V, VI) diagnosed with onychomatricoma and to compare the findings with previously reported cases. Methods: The medical records of 24 patients with dark skin phototype, and a diagnosis of onychomatricoma, collected from 2015 to 2023, were reviewed and analyzed. Results: Thirteen tumors (54.17%) occurred in the fingers and eleven tumors (45.83%) in the toenails. The main clinical and dermoscopic features found were increased nail thickness (21 cases; 88%), xanthonychia (20 cases; 83%), longitudinal melanonychia (18 cases; 75%), transverse hypercurvature of the nail plate (18 cases; 75%), and free edge cavitations (18 cases; 75%). Conclusion: The clinical and dermoscopic features of onychomatricoma in patients with dark phototypes are similar to those in fair phototypes, except for the higher prevalence of melanonychia (75% vs. 24.2%).
Journal Section:
Brief Report
References
1.
Baran
R
, Kint
A
. Onychomatrixoma. Filamentous tufted tumour in the matrix of a funnelshaped nail: a new entity (report of three cases)
. Br J Dermatol
. 1992
;126
:510
–5
. 2.
Tavares
GT
, Chiacchio
NGD
, Chiacchio
ND
, Souza
MV
. Onychomatricoma: a tumor unknown to dermatologists
. An Bras Dermatol
. 2015
;90
(2
):265
–7
. 3.
Di Chiacchio
N
, Tavares
GT
, Tosti
A
, Di Chiacchio
NG
, Di Santis
E
, Alvarenga
L
, et al. Onychomatricoma: epidemiological and clinical findings in a large series of 30 cases
. Br J Dermatol
. 2015
;173
(5
):1305
–7
. 4.
Haneke
E
, Franken
J
. Onychomatricoma
. Dermatol Surg
. 1995
;21
(11
):984
–7
. 5.
Duhard
EBC
, Monegier du Sorbier
C
. Onychomatricome: deux nouveaux cas
. Nouv Dermatol
. 1996
;15
:461
.6.
Perrin
C
, Goettmann
S
, Baran
R
. Onychomatricoma: clinical and histopathologic findings in 12 cases
. J Am Acad Dermatol
. 1998
;39
(4 Pt 1
):560
–4
. 7.
Raison‐Peyron
N
, Alirezai
M
, Meunier
L
, Barneon
G
, Meynadier
J
. Onychomatricoma: an unusual cause of nail bleeding
. Clin Exp Dermatol
. 1998
;23
(3
):138
. 8.
Van Holder
C
, Dumontier
C
, Abimelec
P
. Onychomatricoma
. J Hand Surg Br
. 1999
;24
:120
–1
. 9.
Fraga
GR
, Patterson
JW
, McHargue
CA
. Onychomatricoma: report of a case and its comparison with fibrokeratoma of the nailbed
. Am J Dermatopathol
. 2001
;23
(1
):36
–40
. 10.
Lesort
C
, Debarbieux
S
, Duru
G
, Dalle
S
, Poulhalon
N
, Thomas
L
. Dermoscopic features of onychomatricoma: a study of 34 cases
. Dermatology
. 2015
;231
(2
):177
–83
. 11.
Durrant
MN
, Palla
BA
, Binder
SW
. Onychomatricoma: a case report with literature review
. Foot Ankle Spec
. 2012
;5
(1
):41
–4
. 12.
Lee
DY
. The relation of onychomatricoma to onychodermis in the nail unit
. Ann Dermatol
. 2013
;25
(3
):394
–5
. 13.
Lee
D
. Onychomatricoma is a tumour of nail matrix onychofibroblasts within the onychodermis: association with up-regulation of Wnt/β-catenin signalling
. Histopathology
. 2023
;83
(5
):824
. 14.
Liu
Y
, Zou
D
, Huang
Q
, Wang
L
. RB1 loss in the mesenchymal component of onychomatricoma
. J Cutan Pathol
. 2023
;50
(12
):1094
–8
. 15.
Tosti
A
, Piraccini
BM
, Calderoni
O
, Fanti
PA
, Cameli
N
, Varotti
E
. Onychomatricoma: report of three cases, including the first recognized in a colored man
. Eur J Dermatol
. 2000
;10
(8
):604
–6
.16.
Joshi
TP
, Dunn
C
, Huttenbach
YT
, Kim
SJ
. Onychomatricoma in a patient with skin of color
. JAAD Case Rep
. 2023
;41
(41
):44
–5
. 17.
Piraccini
BM
, Antonucci
A
, Rech
G
, Starace
M
, Misciali
C
, Tosti
A
. Onychomatricoma: first description in a child
. Pediatr Dermatol
. 2007
;24
(1
):46
–8
. 18.
Geizhals
S
, Magro
CM
, Lipner
SR
. Dermatoscopy of onychomatricoma: tortuous hairpin vessels
. Skinmed
. 2022
;20
(6
):444
.19.
Soto
R
, Wortsman
X
, Corredoira
Y
. Onychomatricoma: clinical and sonographic findings
. Arch Dermatol
. 2009
;145
(12
):1461
–2
. 20.
Fraga
G
, Patterson
J
, McHargue
C
. Onychomatricoma: report of a case and its comparison with fibrokeratoma of the nailbed
. Am J Dermatopathol
. 2001
;23
(1
):36
–40
. 21.
Miteva
M
, de Farias
DC
, Zaiac
M
, Romanelli
P
, Tosti
A
. Nail clipping diagnosis of onychomatricoma
. Arch Dermatol
. 2011
;147
(9
):1117
–8
. 22.
Perrin
C
, Baran
R
, Balaguer
T
, Chignon-Sicard
B
, Cannata
GE
, Petrella
T
, et al. Onychomatricoma: new clinical and histological features. A review of 19 tumors
. Am J Dermatopathol
. 2010
;32
:1
–8
. 23.
Kallis
P
, Tosti
A
. Onychomycosis and onychomatricoma
. Skin Appendage Disord
. 2016
;1
(4
):209
–12
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