Introduction: Alopecia areata exhibits diverse clinical forms, encompassing the less common variant, sisaipho. Clinical observations suggest its unique ability to emulate both male and female pattern hair loss, implying a potential androgenic influence akin to androgenetic alopecia. Case Presentations: Herein, we present 3 cases of alopecia areata in adults exhibiting a male or female pattern distribution or accentuation. Conclusion: To improve diagnosis and differential diagnosis of alopecia, the term “alopecia areata in a male or female pattern distribution” may be introduced as a new clinical subtype of alopecia areata. This new subtype could also integrate sisaipho. By introducing this refined terminology, we seek to improve our comprehension of the condition, enabling more precise diagnoses and tailored treatment approaches.

Journal Section:
Novel Insights from Clinical Practice
Keywords:
Alopecia areata, Sisaipho, Male pattern hair loss, Female pattern hair loss, Androgenetic alopecia
1.
Muñoz
MA
,
Camacho
FM
.
Sisaipho: a new form of presentation of alopecia areata
.
Arch Dermatol
.
1996
;
132
(
10
):
1255
–
6
.
Google Scholar
Crossref
Search ADS
PubMed
 
2.
Al-Dhubaibi
MS
,
Alsenaid
A
,
Alhetheli
G
,
Abd Elneam
AI
.
Trichoscopy pattern in alopecia areata: a systematic review and meta-analysis
.
Skin Res Technol
.
2023
;
29
(
6
):
e13378
.
Google Scholar
Crossref
Search ADS
PubMed
 
3.
Mostaghimi
A
,
Gao
W
,
Ray
M
,
Bartolome
L
,
Wang
T
,
Carley
C
, et al.
Trends in prevalence and incidence of alopecia areata, alopecia totalis, and alopecia universalis among adults and children in a US employer-sponsored insured population
.
JAMA Dermatol
.
2023
;
159
(
4
):
411
–
8
.
Google Scholar
Crossref
Search ADS
PubMed
 
4.
Dainichi
T
,
Iwata
M
,
Kaku
Y
.
Alopecia areata: what’s new in the epidemiology, comorbidities, and pathogenesis
.
J Dermatol Sci
.
2023
112
(
3
):
120
–
7
.
Google Scholar
Crossref
Search ADS
PubMed
 
5.
Katoulis
AC
,
Diamanti
K
,
Sgouros
D
,
Liakou
AI
,
Bozi
E
,
Avgerinou
G
, et al.
Is there a pathogenetic link between frontal fibrosing alopecia, androgenetic alopecia and fibrosing alopecia in a pattern distribution
.
J Eur Acad Dermatol Venereol
.
2018
;
32
(
6
):
e218
–
20
.
Google Scholar
Crossref
Search ADS
PubMed
 
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