...Örjan Källskog; Mats Wolgast A method for mirocatheterization of rat kidneys was developed. The catheter consists of 50–100 µm thick polyethylene tubes, and is inserted into the interlobular or arcuate arteries via a lumbar artery. The technique makes it possible to perfuse a small number...

...N. Duong; P. Vinay; N. Khoury; C. Guern; A. Gougoux The role of renal glutamine synthesis for the rapid decrease in renal ammonia-genesis occurring early in the recovery phase (24 h) of metabolic acidosis was studied in rats. L- Methionine- DL -sulfoximine (MSO), an irreversible inhibitor...

...Abraham P. Provoost; Matthijs van Aken Renal functional adaptation to additional nephrons was studied in rats in which a third kidney was transplanted isogeneically. Total renal function did not increase when an extra kidney was added. Quantitation of the contribution of each kidney, by means...

...Munekazu Gemba; Akemi Tachibana; Kumi Sugihara; Mitsuhiko Hori; Mayumi Nakajima The effect of lithium on p -aminohippurate (PAH) transport was studied using slices and basolateral membrane vesicles prepared from rat kidney cortex. The addition of lithium in concentrations ranging from 0.5 to 5 m M...

...Farhad Khalil-Manesh; Robert G. Price The proportion of glomerular basement membrane (GBM) solubilised following pepsin treatment increased with age when the digestion was carried out at 4°C, but remained constant at 50% of the membrane when the digestion was carried out at 10°C irrespective of rat...

...Joan Cho; Rainer G. Galaske; Harvey Arbesman; Judith B. Van Liew The normal filtered load of albumin at the rat glomerulus was estimated to be 18 mg/24 h × g kidney weight by means of micropuncture studies. Total nephron fractional reabsorption was 91%. The proximal convoluted tubule accounted...

... and glucose-6-phosphate dehydrogenase were investigated in kidneys from rats treated with lithium and lithium plus neuroleptics. During the first 8 weeks of lithium treatment the activity of NADH-tetrazolium reductase, succinate dehydrogenase and α-glycerophosphate dehydrogenase activity in the collecting...

... concentrations rose, confirming the activity of adenylate kinase. The control lactate/pyruvate ratio suggested that dog kidney cytosol is more reduced than the cytosol of rat liver and kidney. During ischemia, the lactate concentrations and the lactate/pyruvate ratio of dog renal cortex increased as expected...

...Arvid Hope; Ingvald Tyssebotn; Gunnar Clausén The effect of hemorrhagic hypotension (HH) on local and total renal blood flow was studied in rats. Cortical blood flow, measured as H 2 gas clearance, was determined before and during HH with a mean arterial blood pressure of 50 mm Hg. During...

...Sten Christensen; Bent Hansen Male Wistar rats were treated with lithium added to their food for 11 weeks followed by a withdrawal period of 4 weeks. Urine flow and osmolality were recorded daily. Renal concentrating ability was evaluated from the maximal urine osmolality recorded by the DDAVP test...

...Marie-Marcelle Trinh Trang Tan; Lise Bankir; Mario Diaz; Jean-Pierre Grünfeld Radiolabeled anti-glomerular basement membrane (AGBM) antibody was injected in rats and its distribution was studied in different glomerular populations by microdissection. It was compared with 15 µ mmicrosphere...