..., and duration of therapy after enrolment were recorded. Results: A total of 82 patients has been evaluated. All dose reductions were related to side effects and/or toxicities. The need for a dose reduction was significantly more frequent in patients aged 80 years or older (50 vs. 26.8%, p = 0.039...

... exchanging surface in the peripheral lung. Currently, the primary aims of treatment in COPD are bronchodilation (inhaled short- and long-acting β-agonist and antimuscarinic therapies), to control symptoms and nonspecific broad-acting anti-inflammatory agents (inhaled and oral corticosteroids, phosphor-di...

... for adverse outcomes; a comprehensive approach to asthma management that acknowledges the foundational role of inhaled corticosteroid therapy, but also provides a framework for individualizing patient care; an emphasis on maximizing the benefit of available medications by addressing common problems...

... of therapy with nintedanib was assessed. Results: Forty-one patients with a forced vital capacity (FVC) ≤50% and/or a diffusing capacity of the lung for carbon monoxide (D LCO ) ≤35% predicted at the start of nintedanib treatment were enrolled. At the 6-month follow-up, the decline of D LCO (both absolute...

...-300,000 patients suffer from COPD of GOLD (Global Initiative for Chronic Obstructive Lung Disease) stage II or higher [ 3 ]. Chronic obstructive pulmonary disease Switzerland Exacerbation GOLD ERS Europe Audit Therapy Bundle Recommendations 4 01 2017 30 05 2017 19 7...

... every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug...