...M. Shigyo; H. Aizawa; H. Koto; K. Matsumoto; S. Takata; N. Hara To determine the role of VIP-like peptides on neurotransmission of vagus nerve, we evaluated the effects of helodermin, helospectin, and vasoactive intestinal peptide (VIP) on the contraction of guinea pig tracheal smooth muscle evoked...

..., instructions or products referred to in the content or advertisements. Asthma Inflammation Bronchitis Neutrophils Smooth muscle Respiration I989;55(suppl l):74-78 © 1989 S. Karger ACi. Basel 0014-312X/89/0557-0074 $ 2.75/0 Ambroxol Inhibits Airway Hyperresponsiveness Induced by Ozone in Dogs1 P...

... hyperresponsiveness: a transient component, caused by airway inflammation, and a long-lasting one, unrelated to exposure to acute inflammatory stimuli, which is hypothesized to be due to changes in the autonomic innervation or in the smooth muscle itself. Asthma Bronchial hyperresponsiveness Autonomic...

... by Ca ++ but not by Na + . The results suggest that rapid cooling of the smooth muscle cells causes an increase in sodium conductance and a decrease in the activity of the Na + -K + pump, resulting in membrane depolarization. During depolarization a significant quantity of Ca ++ enters the cell...

... to acetylcholine. Subthreshold concentrations of acetylcholine increased the critical closing pressure by more than 100%. The critical opening pressure was considerably higher than the corresponding closing pressure. It is proposed that bronchiolar closure depends on the tone of the airway smooth muscle...

... noted at 2.52 mM Ca ++ . Passively sensitized muscles did not exhibit this heightened response. Subthreshold tissue chemical mediators are tentatively excluded as causative. An increased sensitivity to extracellular Ca ++ exists in resting smooth muscle following anaphylaxis. 9 04 1979 14 1...

... with terbutaline and the higher doses of dexamethasone, compared with the group treated with terbutaline alone. Conclusion: Our results suggest a negative interaction between high doses of β 2 -adrenergic agonists and glucocorticosteroids in the airway smooth muscle of guinea pigs. β 2 -Adrenergic agonists...