...Roger J. Wolstenholme; S.P. Shettar In a randomized, double-blind, double-dummy, crossover study consisting of two 1-month periods with a 2-week ‘run-in’ we compared the effects of a combination of fenoterol with ipratropium bromide (Duovent®, Boehringer Ingelheim) and salbutamol administered...

...K. Forsberg; J.-A. Karlsson; C. Zackrisson; C.G.A. Persson In guinea-pigs citric acid-induced cough and bronchoconstriction were inhibited by β 2 -agonist and xanthine drugs. Lidocaine inhibited only cough. Cromoglycate and ipratropium bromide inhibited only bronchoconstriction. We conclude...

...Helgo Magnussen; Dennis Nowak; Wolfram Wiebicke We studied the bronchodilator and protective potency of inhaled ipratropium bromide in 33 patients with mild bronchial asthma. Patients were divided into 3 groups with similar baseline lung function and similar degrees of bronchial hyperresponsiveness...

...François Philip-Joet; Marline Reynaud-Gaubert; Jean-Luc Jirou-Najou; Alain Arnaud A 2-month study was carried out to compare the efficacy and safety of Berodual® (B) (Boehringer Ingelheim) and salbutamol (S) in asthma. B is a combined agent with 20 µg of ipratropium bromide and 50 µg of fenoterol...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chronic obstructive lung disease Terbutaline Obstruction reversibility Ipratropium bromide Fenoterol Respiration 50: suppl. 2, pp. 169-172(1986) © 1986 S. Karger AG. Basel UO25...

...E. Marangio; A. Pesci; A. Mori; M. Marchioni; G. Bertorelli We studied the bronchodilator effect of a combination of fenoterol (100 µg) and ipratropium bromide (40 µg) (Duovent) versus salbutamol and placebo in 16 patients with chronic obstructive lung disease (COLD). FEV 1 and the side-effects...

...Kari Sahlström; Kari Alanko; Risto Härkönen The efficacies of inhaled doses of fenoterol 200 µ g, ipratropium bromide 40 µ g and their combination (200 + 40 µ g) were compared in a double-blind, placebo-controlled cross-over study in 24 adult patients with stable asthma bronchiale. The tests were...

...S. Carlone; E. Angelici; P. Palange; W. Shaqadan; G. Luciani; P. Serra Fenoterol with ipratropium bromide (Duovent) is a recently used combination between an anticholinergic and a beta-adrenergic drug useful in obtaining a more effective bronchodilatation and/or reducing the single drug doses...

... -adrenergic drugs is justified, because the dominant mechanism in bronchospasm is the effect of acetylcholine on muscarinic receptors and because ipratropium bromide increases the action of fenoterol, so as to obtain prolonged bronchospasmolytic and antibronchoconstrictive effects with halved doses of beta 2...

... Ipratropium bromide Peak flow 16 1 2009 Respiration 50: suppl. 2, pp. 236-239 (1986) © I986S. Kargcr AG. Basel 0025-7931- 86/0508-0236 S 2.75/0 Double-Blind Study with Duovent and Placebo in 20 Asthmatic Children R. Pulejo, L. Romano, M. Noto P.O. Casa del Sole , U SL60, Palermo, Italy Key...

...P. Simone; M. Robuschi; A. Vaghi; W. Fasano; S. Bianco 16 hyperreactive asthmatics were challenged with an ultrasonic mist of H 2 O at the same time of day on 4 usually consecutive days 2 h after premedication with placebo, fenoterol (200 µ g), ipratropium bromide (80 µg) and Duovent (fenoterol 200...

...A. Bisetti; P. Guerzoni; C. Cavalieri; M. Moretti; C.F. Marchioni The response to an aerosol preparation containing 100 µ g fenoterol and 40 µg ipratropium bromide per puff (Duovent®) was compared with a placebo in 18 asthmatic patients in a double-blind cross-over fashion. We measured changes...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bronchodilators Beta-2-adrenergic agent Bronchial obstruction Fenoterol Ipratropium bromide 16 1 2009...

.... Then saibutamol was administered by a dosimetric aerosol (DA) at the usual dosage (200 µg) and the change in FEV 1 was observed at 60 min; thereafter 40 µg of ipratropium bromide (IB) were administered by DA and FEV 1 was measured after 60 min. Pindolol was administered gradually by mouth (2.5 mg every 30 min...

... to common allergens and not receiving oral steroid treatment. Sensitive spirometric tests were used to evaluate the dose-response effect of inhalation of 0.08, 0.15 or 0.25 mg of ipratropium bromide. The drug caused bronchodilatation with a nearly linear dose-response relationship for static lung volumes...

...G. Fontana; M. Mugnai; F. Cresci; P. Panuccio We examined 12 non-smoking patients affected by extrinsic bronchial asthma in steady state. Histamine PD 20 FEV 1 was assessed 4 h after the administration of salbutamol 200 µ g, a combination of fenoterol 200 µg and ipratropium bromide 80 µ g...

.... Duovent and Carbuterol were given at random on the 1st or 3rd day to each patient; the placebo was always given on the 2nd day. Each drug was administered with 2 puffs of a metered-dose aerosol, corresponding to 200 µ g fenoterol + 80 µ g ipratropium bromide for Duovent and 200 µ g of active substance...

...G. Ciappi; P. Magnini; S. Valente; L. Toscano; G.M Corbo; G. Culla; F. Patalano The beta agonist fenoterol, the antimuscarinic ipratropium bromide and their combination were compared in 10 patients with stable reversible airway obstruction. A single-blind cross-over design was used in order...

...Esko Huhti; Anneli Poukkula Berotec (0.4 mg fenoterol hydrobromide, regimen B), Atrovent (0.08 mg ipratropium bromide, regimen A) and Duovent (0.2 mg fenoterol hydrobromide and 0.08 mg ipratropium bromide, regimen D) were administered by metered dose inhalers (MDI) to 12 patients with asthma...

... was to compare the efficacy of a combination of ipratropium bromide and fenoterol (Duovent) with the activity of single drugs in the prevention of histamine-induced bronchospasm. Twenty-six atopic asthmatic subjects were examined in a double-blind trial, during an asymptomatic period, with a FEV 1 value...