... intolerance in heart failure with reduced ejection fraction (HFrEF) or heart failure with preserved ejection fraction (HFpEF) results from both cardiac dysfunction and skeletal muscle weakness. Respiratory muscle dysfunction with restrictive ventilation disorder may be present irrespective of left ventricular...

... (SVB) and hemodynamics in conditions of decreased cardiac output and feedback resetting, such as heart failure (HF) or pulmonary arterial hypertension (PAH), are not completely understood. Objectives: To investigate the effects of voluntary hyperventilation and simulated PB on hemodynamics and SVB...

...Renaud Tamisier; Victor Bocquillon; Erika Treptow; Marie Destors; Muriel Salvat; Elisabeth Borrel; Jean Louis Pépin Background: Despite clinical optimization, many chronic heart failure (CHF) patients remain symptomatic with dyspnea and poor quality of life. Study Objective: While oxygen therapy...

... with a high economic burden. Heart failure shares some general symptoms with COPD; thus, diagnosing COPD is difficult in subjects with a history of heart failure, and spi-rometry is mandatory for confirmation. Moreover, COPD is a highly prevalent comorbidity negatively impacting the outcome of heart failure...

... circulation and vice versa, patients with sleep-related breathing disorders should be evaluated for risk factors, symptoms and clinical signs of PH and right ventricular heart failure and patients with PH should be evaluated for sleep apnea. Therapeutic options for patients with sleep apnea and PH may include...

... in patients with moderate-to-severe heart failure (HF) and characterized by periodical breathing (hyperventilation). Objectives: This study analyzed and compared the acute effects of a novel ASV device on carbon dioxide pressure (pCO 2 ) and oxygen saturation (SaO 2 ) in HF patients with CSR and healthy...

...Christoph Birner; Frederic Series; Keir Lewis; Amit Benjamin; Silke Wunderlich; Pierre Escourrou; Florian Zeman; Ruth Luigart; Michael Pfeifer; Michael Arzt Background: Systolic heart failure (HF) is frequently accompanied by diastolic dysfunction and sleep-disordered breathing (SDB). Objectives...

...Thomas Brack; Winfried Randerath; Konrad E. Bloch Cheyne-Stokes respiration (CSR) is characterized by a pattern of cyclic oscillations of tidal volume and respiratory rate with periods of hyperpnea alternating with hypopnea or apnea in patients with heart failure. CSR harms the failing heart...

... of selective β 1 -blockers in patients with CVD and especially in heart failure (HF), they are still largely underused, mostly as a consequence of the presence of chronic obstructive pulmonary disease (COPD). In primary care, prevalence of COPD in patients with HF is approximately 25%, and it will rise...

... sensitized. PCA has been demonstrated in various lung diseases, including exudative pleural effusions. To determine the value of measuring cell-bound PCA in the diagnosis of tuberculous pleural effusions we examined pleural effusion MNC of patients with tuberculosis (n = 19), congestive heart failure (n = 7...

...Clifford W. Barlow; Mohammed S. Qayyum; Patrick P. Davey; David J. Peterson; Peter A. Robbins We studied the acute ventilatory response to hypoxia (AHVR) in 10 patients with chronic heart failure (CHF) and in 10 subjects with normal left ventricular function (NLVF) before and after 8 weeks of home...

...F. Sabino; L. Bianco; V. Cantoni; P. Ghirardi; G.V. Marchetti; V. Cicchetti A group of 36 patients with cor pulmonale chronicum were treated for 12 months with ibopamine, a dopamine-related drug, orally active, suitable for the long-term therapy of congestive heart failure. In heart failure due...

... evaluations in detecting left heart failure (LHF). Patients with elevation in mean pulmonary artery wedge pressure (PAWM) ≥ 20 mm Hg had significant restrictive changes with reduction in vital capacity (VC), forced expiratory volume in 1 s (FEV 1.0 ), and total lung capacity (TLC) measured by helium dilution...

...Stephan Steiner; Christiana M. Schannwell; Bodo E. Strauer Background: Continuous positive airway pressure (CPAP) may be a useful adjunct in patients with congestive heart failure. Objectives: To evaluate the relationship between left ventricular geometry and hemodynamic response to CPAP. Methods...

...C. Andrew Schroeder; David L. Balfe; Steven S. Khan; Zab Mohsenifar Background: Congestive heart failure (CHF) patients experience dyspnea on exertion and therefore have decreased exercise tolerance. Objective: This study explores the hypothesis that stable New York Heart Association (NYHA) class...

... of NO production. Bronchial hyperresponsiveness (BHR) has been reported in patients with cardiac diseases [ 1, 2, 3, 4, 5, 6 ]. The mechanisms underlying cardiac BHR is poorly understood. We and other investigators recently observed BHR in patients with congestive heart failure [ 1, 2, 3, 4 ]and vasospastic...