... to in the content or advertisements. 2023 Bronchoscopy Cryobiopsy Interstitial lung disease Diagnosis Fibrosis Accurately diagnosing interstitial lung diseases (ILDs) may be challenging given their variable features, which are usually not pathognomonic and can overlap between the entities [ 1...

...Nikolaos Manitsopoulos; Ioanna Nikitopoulou; Nikolaos A. Maniatis; Christina Magkou; Anastasia Kotanidou; Stylianos E. Orfanos Background: Pulmonary fibrosis is a chronic disease, which progressively leads to respiratory failure and ultimately death. Endothelin-1 (ET-1), a vasoconstrictor secreted...

...Jacob Hull Kristensen; Morten Asser Karsdal; Federica Genovese; Simon Johnson; Birte Svensson; Susanne Jacobsen; Per Hägglund; Diana Julie Leeming This review discusses the role of extracellular matrix (ECM) quality in the pathogenesis of pulmonary fibrosis (PF). In PF, the highly ordered structure...

...M. Kolb; Keren Borensztajn; Bruno Crestani; Martin Kolb Idiopathic pulmonary fibrosis (IPF) is the most frequent fibrotic diffuse parenchymal lung disease. Its prognosis is devastating: >50% of the patients die within 3 years after diagnosis. Options for the treatment of IPF are limited and lung...

...Shifeng Li; Xiaoxiao Yang; Wande Li; Jingjie Li; Xingwen Su; Lijun Chen; Guangmei Yan Background: Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease without beneficial therapy, except for lung transplantation. A high oral dose of N-acetylcysteine (NAC) added to prednisone...

...Smaragda Oikonomidi; Konstantinos Kostikas; Ioannis Kalomenidis; Irene Tsilioni; Christos Daenas; Konstantinos I. Gourgoulianis; Theodoros S. Kiropoulos Background: Matrix metalloproteinases (MMPs) have been implicated in the escalation of fibrosis and remodeling which are central to the subsequent...

...José Perez Neria; Moises Selman Lama; Horacio Rubio Monteverde; Hector Ocaña S.; Rocio Chapela Mendoza; Andres Mendoza Mendoza In order to find a physiological parameter which discriminates between the predominance of inflammation or fibrosis, pulmonary function tests and open lung biopsy were...

...M. Myre; S. Allard; C. Bernard; R.R. Martin We describe the clinical, physiological and pathological features of 23 subjects with early stage idiopathic pulmonary fibrosis. Thirteen subjects who had no symptoms had been fortuitously recruited by a routine chest radiograph, whereas the 10 other...

.... Mediastinal Histoplasmosis Heart Fibrosis Familial Respiration 43: 232-239 (1982) Mediastinal Histoplasmosis A Study of Two Brothers with Emphasis on Invasion of the Heart M . Myre, S. Allard Sacre-Cceur Hospital. Montreal, Que., Canada Key Words. Mediastinal Histoplasmosis Heart Fibrosis...

...Gildo D. Renzi; Vincent Lopez-Majano 2 cases of interstitial fibrosis of the Hamman-Rich type are presented. The patients were symptomatic, but had normal X-rays. They were suspected of having interstitial infiltration by pulmonary function tests. Diagnosis was confirmed by lung biopsy. Pulmonary...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Systemic sclerosis Nonspecific interstitial pneumonia Lung Fibrosis Matrix remodeling Vascular activity Angiogenesis Systemic sclerosis (SSc) is a connective tissue disease...

... and remodeling of the lungs, heart and skin. Objective: We postulated that chymase gene (CMA1) polymorphisms are associated with pulmonary fibrosis in Dutch and with cardiac and skin involvement in Japanese sarcoidosis patients. Patients and Methods: Dutch (n = 153) and Japanese (n = 122) sarcoidosis patients...

...N. Berkman; S. Kremer; R. Or; I.S. Lossos; T.G. Christensen; R.H. Goldstein; R. Breuer Background: Bleomycin (Bleo)-induced lung injury in mice serves as an animal model of pulmonary fibrosis. The pathogenesis of pulmonary fibrosis remains unclear, but it comprises both inflammatory and fibrotic...