... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chronic obstructive pulmonary disease Clinical trials Bronchodilators Drug development Chronic obstructive pulmonary disease (COPD) has long been a leading cause...

..., the disease was appreciated as one of excess phlegm. Early remedies included garlic, pepper, cinnamon, and turpentine, whereas later therapies of choice emphasized coffee, ipecac, and potassium nitrate. Most of the favored bronchodilator drugs of today are derived from the traditional folk remedies, ephedrine...

... separately, no significant differences in any parameter measured (other than radioaerosol penetrance which was significantly enhanced on oxitropium bromide in chronic bronchitics) were noted between the three assessments Anticholinergic drugs Bronchodilators Lung mucociliary clearance Mucus Oxitropium...

... < 0.01). With F+ IB, V max25 increased since after 15 min (p < 0.001) and up to 60 min (p < 0.01). In conclusion, the association of a small dose of F to IB provides as positive results as S, and better than T, in a group of chronic bronchitic out-patients. 16 1 2009 Bronchodilators...

... at regular intervals during the 90-day study. In all instances the day-one bronchodilator response was significant, prompt and sustained: at 1, 4, 8 and 12 weeks the response was statistically the same as on day 1. It is concluded that, when the important variables are properly controlled, no evidence...

.... Bronchodilators Ipratropium bromide Fenoterol Metered aerosol Lung function tests 16 1 2009 © 1986 S. Karger AG, Basel 1986 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any...

...S. Macaluso; L. Del Torre Duovent and salbutamol were compared in 15 patients with stabilized, but partially reversible chronic bronchospasm to verify the persistence of therapeutic effect, bronchodilator efficacy and patient compliance to prolonged treatment with these drugs. Results showed: (1...

...C. Serra; A. Giacopelli; G. Luciani A double-blind study was carried out in a group of 9 patients with partially reversible airway obstruction, to evaluate the bronchodilator effect of gradually increased doses of fenoterol (cumulative doses: 100, 200, 400, 800 and 1,600 µg), ipratropium bromide...

... of inhalation Bronchodilators Respiration 45: 56-60(1984) © 1984 S. Karger A G . Basel 0025-7931/84/0451 -0056 S 2.75/0 Mode of Inhalation for Trained and Untrained Asthmatics Using a Pressurized Aerosol Folke Moren, Jan Andersson, Goran Stiksa AB Draco, Research and Development Laboratories, Lund, Sweden...

...Antonio Cutillo; Rodolfo Perondi; Maurizio Turiel; Suetaro Watanabe; Attilio D. Renzetti, Jr The effects of bronchodilator treatment (intravenous atropine or inhaled metaproterenol) on the behavior of pulmonary resistance (R L ) and dynamic compliance (Cdyn) as functions of respiratory frequency...

...A. Muittari The development of β 2 -specific sympathomimetic bronchodilators (rimiterol, salbutamol, terbutaline) has made the basic treatment of asthmatic patients more safe and effective. Despite that, the asthmatics should be under careful control and all patients should be taught the correct...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Bronchoconstriction Bronchodilators Flow-volume curves Pulmonary...

..., instructions or products referred to in the content or advertisements. Ventilatory mechanics Airway conductance Asthma Bronchodilators Adrenergic beta-stimulants Respiration 29: 247-256 (1972) Influence de la valeur fonctionnelle de départ sur l effet bronchodilatateur d'un stimulant bêta...

...-blind, placebo-controlled trial. Patients were randomly assigned to receive nebulized salbutamol, ipratropium bromide or placebo. Main outcome measures were changes in oxygen saturation rates and clinical scores and duration of hospitalization. Results: In the bronchodilator groups, clinical scores were...

... existing compounds include: isomers of the long-acting bronchodilators, once-daily b 2 -adrenoceptor agonists, anticholinergics and corticosteroids. The pool of novel compounds is in constant fluctuation and comprises anti-inflammatory drugs, antioxidants, leukotriene modifiers and a number of compounds...

... formoterol and total formoterol increased with dose delivered via the Certihaler. The optimum dose of formoterol via the Certihaler was 10 µg. Conclusion: Delivery of formoterol via the Certihaler or Aerolizer combines rapid relief with enduring control and provides convenient bronchodilation in patients...

... undertaken to assess the use of specific airway conductance (sG aw ) as a pharmacodynamic endpoint for the comparison of two bronchodilator delivery systems (a novel dry powder inhaler and a standard metered dose inhaler). The first pilot study involved delivery of a single dose of salbutamol (200 µg) to 12...