...Shinichi Tomioka; Munehiro Arai; Hajime Kuroiwa; Ryuzo Fueki; Setsuo Kobayashi We have investigated the effect of nifedipine on acetylcholine-induced bronchoconstriction in 8 asthmatics and on histamine-induced bronchoconstriction in another 8 asthmatics on a single-blind basis. Expiratory...

...Hiroshi Yamamoto; Shuichi Inaba; Masaharu Nishimura; Fujiya Kishi; Yoshikazu Kawakami The ability to detect added resistance at rest was compared to the magnitude of breathlessness (evaluated by a modified Borg scale) during bronchoconstriction in 27 stable asthmatics. Threshold for resistive load...

... examination in clinical pharmacology. We carried out a study using this test in 12 atopic asthmatics in intercritical phase. The patients were treated for a few days before, under double-blind conditions and random order, with Duovent (80 µ g ipratropium bromide + 200 µ g fenoterol), fenoterol (400 µ g...

...K.T. Khoo; C.K. Connolly Bronchial lability was measured in 10 normal subjects, 33 typical asthmatics, and 23 smokers with ventilatory defect, by three different methods in the course of a week. There was little difference between exercise/bronchodilator lability index, spontaneous diurnal...