Background: Pulmonary lipomas are rare benign tumors that are usually found endobronchially. Undiagnosed, they can lead to the serious late sequelae associated with endobronchial obstruction. In the majority of cases, they are located in the first three subdivisions of the tracheobronchial tree, and therefore, they are amenable to endoscopic techniques for diagnostic and therapeutic purposes. Objectives: It was our aim to retrospectively study the bronchoscopic management and follow-up of a large series of endobronchial lipomas, as well as defining the demographic and endoscopic characteristics of patients. Methods: A retrospective multicenter study was performed to identify all cases of lipomas that were treated endoscopically in 4 institutions in the period from 1981 to 2002. Demographic, radiological, endoscopic and histological data were collected. Results: Thirty-eight patients were included in the study; 81.6% of cases were males and the average age was 63.5 ± 15.2 years. The majority of the patients were symptomatic (63.2%). Lipomas were located proximally in 18 cases (47.4%) and distally in 20 subjects (52.6%). Specimens obtained by rigid bronchoscopy were diagnostic in all cases. Thirty-six out of 38 patients underwent therapeutic rigid bronchoscopy. Laser and mechanical debulking was performed in 29 cases (76.3%), cryotherapy and mechanical debulking in 7 subjects (18.4%), and mechanical debulking alone in 2 cases (5.3%). No cases of recurrence occurred during the follow-up period. Conclusions: This study demonstrates that endoscopic techniques are effective for the diagnosis and treatment of endobronchial lipomas when there is no evidence of severe distal bronchiectasis. This should be the treatment of choice after a full clinicoradiological evaluation.

Shah H, Garbe L, Nussbaum E, Dumon JF, Chiodera PL, Cavaliere S: Benign tumors of the tracheobronchial tree. Endoscopic characteristics and role of laser resection. Chest 1995;107:1744–1751.
Politis J, Funahashi A, Gehlsen JA, DeCock D, Stengel BF, Choi H: Intrathoracic lipomas. Report of three cases and review of the literature with emphasis on endobronchial lipoma. J Thorac Cardiovasc Surg 1979;77:550–556.
Gaerte SC, Meyer CA, Winer-Muram HT, Tarver RD, Conces DJ Jr: Fat-containing lesions of the chest. Radiographics 2002;22:S61–S78.
Muraoka M, Oka T, Akamine S, et al: Endobronchial lipoma: review of 64 cases reported in Japan. Chest 2003;123:293–296.
Drira I, Souissi R, Horchani H, Kilani T, Labbene N, Chebbi ML: Endo-bronchial lipoma. Apropos of a case. Rev Pneumol Clin 1995;51:247–249.
Poirier NC, Perrault LP, Beauchamp G, Filion R: Endoscopic removal of a right lower lobe bronchial lipoma in a high-risk patient: a case report. Can J Surg 1994;37:411–414.
Box K, Kerr KM, Jeffrey RR, Douglas JG: Endobronchial lipoma associated with lobar bronchiectasis. Respir Med 1991;85:71–72.
Yokozaki M, Kodama T, Yokose T, et al: Endobronchial lipoma: a report of three cases. Jpn J Clin Oncol 1996;26:53–57.
Destito C, Romagnoli A, Carlucci I, Mercuri M, Vulpio C, Wiel Marin A: Endobronchial lipoma: endoscopic resection or surgical excision? Report of a case and review of the literature. G Chir 1995;16:445–447.
Mailleux P, Fontaine D, Mairesse M, Coulier B, Coppens JP, Joris JP: Endobronchial lipoma: a potential CT diagnosis. J Belge Radiol 1990;73:103–106.
Liam CK, Jayalakshmi P, Kumar G, Awang Y: Endobronchial lipoma simulating bronchogenic carcinoma. Postgrad Med J 1994;70:668.
Simmers TA, Jie C, Sie B: Endobronchial lipoma posing as carcinoma. Neth J Med 1997;51:143–145.
Moran CA, Suster S, Koss MN: Endobronchial lipomas: a clinicopathologic study of four cases. Mod Pathol 1994;7:212–214.
Dogan R, Unlu M, Gungen Y, Moldibi B: Endobronchial lipoma. Thorac Cardiovasc Surg 1988;36:241–243.
Nataf P, Gharbi N, Bourcereau J, et al: Endobronchial lipomas. Apropos of 16 cases. Rev Pneumol Clin 1989;45:203–205.
Huisman C, van Kralingen KW, Postmus PE, Sutedja TG: Endobronchial lipoma: a series of three cases and the role of electrocautery. Respiration 2000;67:689–692.
Suzuki N, Takizawa H, Yamaguchi M, et al: A case of asymptomatic endobronchial lipoma followed for 4 years. Nihon Kyobu Shikkan Gakkai Zasshi 1992;30:1879–1883.
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