Measurements of mean pulmonary artery pressure (MPAP) and alveolar oxygen tension (p A02) in normal man at 8 altitudes between sea level and 17,100 ft and predicted values for similar altitudes were compared in a computer program which calculated linear regression slopes and intercepts and plotted the regression line as well as the constants of linear regression equations. p AO2 predictions were derived from the linear regression slope of actual p AO2 and altitude; and MPAP predictions were based on an empirical formula using inspired oxygen tension (p AO2), the ratios of ambient and sea-level barometric pressure, and predicted p A02. There was highly significant positive linear correlation between predicted MPAP and altitude, predicted and measured MPAP, and predicted and measured p A02, and highly significant negative linear correlation between actual p A02 and altitude. Measured mean p AO2 and MPAP of newcomers were within 2 SE of those for natives of the same altitude.

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© 1970 S. Karger AG, Basel
1970
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