Introduction: Chronic obstructive pulmonary disease (COPD) is highly prevalent and underdiagnosed worldwide. The validity and reliability of COPD Population Screening (COPD-PS) questionnaire are not properly known in a large-sample Chinese population. Methods: This is a national multicenter prospective study that enrolled 1,824 outpatients from 12 hospital sites in China. Scores of the Chinese version of COPD-PS questionnaire, demographic data, and clinical information were collected. The validity and the test-retest reliability were evaluated. Results: 1,824 participants were involved in this study, and 404 (22.1%) were diagnosed with COPD. The overall area under the curve (AUC) of the receiver operating characteristic (ROC) for COPD-PS questionnaire was 0.761 (95% CI: 0.734–0.787). A cut-off point of 4 was recommended, corresponding to a sensitivity of 74.50% and a specificity of 64.37%. The COPD-PS questionnaire showed an overall Pearson’s correlation of 0.88. Conclusions: The COPD-PS questionnaire can be used in screening COPD patients from the general Chinese population with respiratory symptoms.

1.
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease 2021 report
. Available from: https://goldcopd.org/wp-content/uploads/2020/11/GOLD-REPORT-2021-v1.1-25Nov20_WMV.pdf (accessed Dec 1, 2020).
2.
Lozano
R
,
Naghavi
M
,
Foreman
K
,
Lim
S
,
Shibuya
K
,
Aboyans
V
.
Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010
.
Lancet
.
2012
;
380
(
9859
):
2095
128
.
3.
Soriano
JB
,
Abajobir
AA
,
Abate
KH
,
Abera
SF
,
Agrawal
A
,
Ahmed
MB
.
Global, regional, and national deaths, prevalence, disability-adjusted life years, and years lived with disability for chronic obstructive pulmonary disease and asthma, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015
.
Lancet Respir Med
.
2017
;
5
(
9
):
691
706
.
4.
Wang
C
,
Xu
J
,
Yang
L
,
Xu
Y
,
Zhang
X
,
Bai
C
.
Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health CPH study): a national cross-sectional study
.
Lancet
.
2018
;
391
(
10131
):
1706
17
.
5.
Lamprecht
B
,
Soriano
JB
,
Studnicka
M
,
Kaiser
B
,
Vanfleteren
LE
,
Gnatiuc
L
.
Determinants of underdiagnosis of COPD in national and international surveys
.
Chest
.
2015
;
148
(
4
):
971
85
.
6.
Koblizek
V
,
Novotna
B
,
Zbozinkova
Z
,
Hejduk
K
.
Diagnosing COPD: advances in training and practice – a systematic review
.
Adv Med Educ Pract
.
2016
;
7
:
219
31
.
7.
Guirguis-Blake
JM
,
Senger
CA
,
Webber
EM
,
Mularski
R
,
Whitlock
EPUS
.
Preventive services task force evidence syntheses, formerly systematic evidence reviews
.
Screening for chronic obstructive pulmonary disease: a systematic evidence review for the US preventive services task force
Rockville (MD)
Agency for Healthcare Research and Quality (US)
2016
.
8.
Martinez
FJ
,
Raczek
AE
,
Seifer
FD
,
Conoscenti
CS
,
Curtice
TG
,
D’Eletto
T
.
Development and initial validation of a self-scored COPD population screener questionnaire (COPD-PS)
.
COPD
.
2008
;
5
(
2
):
85
95
.
9.
Miravitlles
M
,
Llor
C
,
Calvo
E
,
Diaz
S
,
Díaz-Cuervo
H
,
Gonzalez-Rojas
N
.
Validation of the Spanish version of the chronic obstructive pulmonary disease-population screener (COPD-PS). Its usefulness and that of FEV1/FEV6 for the diagnosis of COPD
.
Med Clin
.
2012
;
139
(
12
):
522
30
.
10.
Tsukuya
G
,
Matsumoto
K
,
Fukuyama
S
,
Crawford
B
,
Nakanishi
Y
,
Ichinose
M
.
Validation of a COPD screening questionnaire and establishment of diagnostic cut-points in a Japanese general population: the Hisayama study
.
Allergol Int
.
2015
;
64
(
1
):
49
53
.
11.
Llordés
M
,
Zurdo
E
,
Jaén
Á
,
Vázquez
I
,
Pastrana
L
,
Miravitlles
M
.
Which is the best screening strategy for COPD among smokers in primary care
.
COPD
.
2017
;
14
(
1
):
43
51
.
12.
Gu
Y
,
Zhang
Y
,
Wen
Q
,
Ouyang
Y
,
Shen
Y
,
Yu
H
.
Performance of COPD population screener questionnaire in COPD screening: a validation study and meta-analysis
.
Ann Med
.
2021
;
53
(
1
):
1198
206
.
13.
Zhou
J
,
Yu
N
,
Li
X
,
Wang
W
.
Accuracy of six chronic obstructive pulmonary disease screening questionnaires in the Chinese population
.
Int J Chron Obstruct Pulmon Dis
.
2022
;
17
:
317
27
.
14.
Liu
M
,
Yin
D
,
Wang
Y
,
Wang
W
,
Fu
T
,
Duan
Y
.
Comparing the performance of two screening questionnaires for chronic obstructive pulmonary disease in the Chinese general population
.
Int J Chron Obstruct Pulmon Dis
.
2023
;
18
:
541
52
.
15.
Terwee
CB
,
Bot
SD
,
de Boer
MR
,
van der Windt
DA
,
Knol
DL
,
Dekker
J
.
Quality criteria were proposed for measurement properties of health status questionnaires
.
J Clin Epidemiol
.
2007
;
60
(
1
):
34
42
.
16.
Jones
PW
,
Harding
G
,
Berry
P
,
Wiklund
I
,
Chen
WH
,
Kline Leidy
N
.
Development and first validation of the COPD assessment test
.
Eur Respir J
.
2009
;
34
(
3
):
648
54
.
17.
Fluss
R
,
Faraggi
D
,
Reiser
B
.
Estimation of the Youden Index and its associated cutoff point
.
Biom J
.
2005
;
47
(
4
):
458
72
.
18.
Stolz
D
,
Mkorombindo
T
,
Schumann
DM
,
Agusti
A
,
Ash
SY
,
Bafadhel
M
.
Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission
.
Lancet
.
2022
;
400
(
10356
):
921
72
.
19.
Hu
X
,
Li
C
,
Chen
J
,
Qin
G
.
Confidence intervals for the Youden index and its optimal cut-off point in the presence of covariates
.
J Biopharm Stat
.
2021
;
31
(
3
):
251
72
.
20.
Schnieders
E
,
Ünal
E
,
Winkler
V
,
Dambach
P
,
Louis
VR
,
Horstick
O
.
Performance of alternative COPD case-finding tools: a systematic review and meta-analysis
.
Eur Respir
.
2021
;
30
(
160
):
200350
.
You do not currently have access to this content.