Abstract
Robotic platforms have been widely used in the various fields of clinical diagnosis and therapy of diseases in the past decade. Robotic-assisted bronchoscopy (RAB) demonstrates its advantages of visibility, flexibility, and stability in comparison to conventional bronchoscopic techniques. Improving diagnostic yield and navigation yield for peripheral pulmonary lesions has been defined; however, RAB platform of treatment was not reported. In this article, we report a case of a 52-year-old woman who was diagnosed with the tracheal adenoid cystic carcinoma and recurred in the second postoperative year, leading to the involvement of the entire tracheal wall and lumen obstruction. Since the lesion was inoperable, we combined RAB and photodynamic therapy (PDT) for the patient. The potential advantages of using RAB for PDT delivery include precise light irradiation of target lesions and stable intra-operative control over the long term. This is a novel application of RAB combined with PDT for airway diseases. The case report may provide a new insight into the diagnosis and treatment of pulmonary diseases. In addition to improving the diagnostic rates, the RAB platform may also play an important role in the treatment of airway and lung disease in the future.
Journal Section:
Novel Insights from Clinical Practice
References
1.
Peters
BS
, Armijo
PR
, Krause
C
, Choudhury
SA
, Oleynikov
D
. Review of emerging surgical robotic technology
. Surg Endosc
. 2018
;32
(4
):1636
–55
.2.
Fiorelli
A
, Mazzone
S
, Costa
G
, Santini
M
. Endoscopic treatment of idiopathic subglottic stenosis with digital AcuBlade robotic microsurgery system
. Clin Respir J
. 2018 Feb
12
2
802
5
.3.
Kalchiem-Dekel
O
, Connolly
JG
, Lin
IH
, Husta
BC
, Adusumilli
PS
, Beattie
JA
et al. Shape-sensing robotic-assisted bronchoscopy in the diagnosis of pulmonary parenchymal lesions
. Chest
. 2022
;161
(2
):572
–82
.4.
Lu
M
, Nath
S
, Semaan
RW
. A review of robotic-assisted bronchoscopy platforms in the sampling of peripheral pulmonary lesions
. J Clin Med
. 2021
;10
(23
):5678
.5.
Oberg
CL
, Lau
RP
, Folch
EE
, He
T
, Ronaghi
R
, Susanto
I
et al. Novel robotic-assisted cryobiopsy for peripheral pulmonary lesions
. Lung
. 2022
;200
(6
):737
–45
.6.
Chen
AC
, Pastis
NJ
, Machuzak
MS
, Gildea
TR
, Simoff
MJ
, Gillespie
CT
et al. Accuracy of a robotic endoscopic system in cadaver models with simulated tumor targets: ACCESS study
. Respiration
. 2020
;99
(1
):56
–61
.7.
Chen
AC
, Pastis
NJ
, Mahajan
AK
, Khandhar
SJ
, Simoff
MJ
, Machuzak
MS
et al. Robotic bronchoscopy for peripheral pulmonary lesions: a multicenter pilot and feasibility study (BENEFIT)
. Chest
. 2021
;159
(2
):845
–52
.8.
Scarlata
S
, Fuso
L
, Lucantoni
G
, Varone
F
, Magnini
D
, Antonelli Incalzi
R
et al. The technique of endoscopic airway tumor treatment
. J Thorac Dis
. 2017
;9
(8
):2619
–39
.9.
Allison
RR
, Bansal
S
. Photodynamic therapy for peripheral lung cancer
. Photodiagnosis Photodyn Ther
. 2022
;38
:102825
.10.
Ji
W
, Yoo
JW
, Bae
EK
, Lee
JH
, Choi
CM
. The effect of Radachlorin® PDT in advanced NSCLC: a pilot study
. Photodiagnosis Photodyn Ther
. 2013
;10
(2
):120
–6
.11.
Akopov
A
, Rusanov
A
, Gerasin
A
, Kazakov
N
, Urtenova
M
, Chistyakov
I
. Preoperative endobronchial photodynamic therapy improves resectability in initially irresectable (inoperable) locally advanced non small cell lung cancer
. Photodiagnosis Photodyn Ther
. 2014
;11
(3
):259
–64
.12.
Usuda
J
, Inoue
T
, Tsuchida
T
, Ohtani
K
, Maehara
S
, Ikeda
N
et al. Clinical trial of photodynamic therapy for peripheral-type lung cancers using a new laser device in a pilot study
. Photodiagnosis Photodyn Ther
. 2020
;30
:101698
.13.
Maziak
DE
. Biology of adenoid cystic carcinoma of the tracheobronchial tree and principles of management
. Thorac Surg Clin
. 2018
;28
(2
):145
–8
.14.
Bansal
S
, Bechara
RI
, Patel
JD
, Mehta
HJ
, Ferguson
JS
, Witt
BL
et al. Safety and feasibility of photodynamic therapy for ablation of peripheral lung tumors
. J Bronchology Interv Pulmonol
. 2023
;30
(2
):135
–43
.15.
Chen
KC
, Lee
JM
. Photodynamic therapeutic ablation for peripheral pulmonary malignancy via electromagnetic navigation bronchoscopy localization in a hybrid operating room (OR): a pioneering study
. J Thorac Dis
. 2018
10
Suppl 6
S725
30
.16.
Liu
Y
, Wang
F
, Zhang
Q
, Tong
Z
. Diagnostic yield of virtual bronchoscope navigation combined with radial endobronchial ultrasound guided transbronchial cryo-biopsy for peripheral pulmonary nodules: a prospective, randomized, controlled trial
. Ann Transl Med
. 2022
;10
(8
):443
.17.
Yuan
HB
, Wang
XY
, Sun
JY
, Xie
FF
, Zheng
XX
, Tao
GY
et al. Flexible bronchoscopy-guided microwave ablation in peripheral porcine lung: a new minimally-invasive ablation
. Transl Lung Cancer Res
. 2019
;8
(6
):787
–96
.18.
Xie
F
, Chen
J
, Jiang
Y
, Sun
J
, Hogarth
DK
, Herth
FJF
. Microwave ablation via a flexible catheter for the treatment of nonsurgical peripheral lung cancer: a pilot study
. Thorac Cancer
. 2022
;13
(7
):1014
–20
.© 2023 S. Karger AG, Basel
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
2023
You do not currently have access to this content.
