Background: Despite its high prevalence in all psychiatric disorders and its widely demonstrated clinical relevance as a marker of both clinical severity and poorer treatment response, a scientifically validated definition of dissociation remains controversial, and the understanding of its pathogenesis is still somewhat lacking. Furthermore, although most clinicians commonly refer to dissociation as a single unitary concept, the empirical evidence strongly supports the paucity of a one-dimensional approach to dissociation. Summary: Resonating with the clinical and neuroscientific data on this topic, this article aimed to provide a working hypothesis, suggesting that the wide variety of psychopathological phenomena that are currently improperly lumped into the category of dissociation are in fact produced by at least three different pathogenic processes involved in developmental trauma, namely, traumatic disintegration, detachment responses, and dissociation. Key Messages: This hypothesis should, therefore, be considered a starting point for a better understanding of the complex manifestations and processes that currently overly, attributed to dissociation per se.

1.
Lebois
LAM
,
Li
M
,
Baker
JT
,
Wolff
JD
,
Wang
D
,
Lambros
AM
et al
.
Large-scale functional brain network architecture changes associated with trauma-related dissociation
.
Am J Psychiatry
.
2021
;
178
(
2
):
165
73
.
2.
Ellickson-Larew
S
,
Stasik-O’Brien
SM
,
Stanton
K
,
Watson
D
.
Dissociation as a multidimensional transdiagnostic symptom
.
Psychol Conscious Theor Res Pract
.
2020
;
7
(
2
):
126
50
.
3.
Lyssenko
L
,
Schmahl
C
,
Bockhacker
L
,
Vonderlin
R
,
Bohus
M
,
Kleindienst
N
.
Dissociation in psychiatric disorders: a meta-analysis of studies using the dissociative experiences scale
.
Am J Psychiatry
.
2018
;
175
(
1
):
37
46
.
4.
Vonderlin
R
,
Kleindienst
N
,
Alpers
GW
,
Bohus
M
,
Lyssenko
L
,
Schmahl
C
.
Dissociation in victims of childhood abuse or neglect: a meta-analytic review
.
Psychol Med
.
2018
;
48
(
15
):
2467
76
.
5.
Farina
B
,
Meares
R
.
The traumatic disintegration dimension
. In:
Dorahy
MJ
,
Gold
SN
,
O’Neil
JA
, editors.
Dissociation and the dissociative disorder: past, present, future
New York
Routledge
.
2022
.
6.
Steele
K
,
Dorahy
M
,
van der Hart
O
.
Dissociation versus alterations in consciousness: related but different concepts
. In:
Dorahy
MJ
,
Gold
SN
,
O’Neil
JA
, editors.
Dissociation and the dissociative disorder: past, present, future
New York
Routledge
.
2022
.
7.
Lynn
SJ
,
Maxwell
R
,
Merckelbach
H
,
Lilienfeld
SO
,
Kloet
DVH
,
Miskovic
V
.
Dissociation and its disorders: competing models, future directions, and a way forward
.
Clin Psychol Rev
.
2019
;
73
:
101755
.
8.
Brown
RJ
.
Commentary on “dissociation in trauma: a new definition and comparison with previous formulations” by nijenhuis and van der hart
.
J Trauma & Dissociation
.
2011
;
12
(
4
):
450
3
; discussion 469-73.
9.
Dalenberg
CJ
,
Brand
BL
,
Gleaves
DH
,
Dorahy
MJ
,
Loewenstein
RJ
,
Cardeña
E
et al
.
Evaluation of the evidence for the trauma and fantasy models of dissociation
.
Psychol Bull
.
2012
;
138
(
3
):
550
88
.
10.
Van der Hart
O
,
Nijenhuis
E
,
Steele
K
The haunted self: structural dissociation and the treatment of chronic traumatization
New York/London
Norton
.
2006
.
11.
Sar
V
,
Akyüz
G
,
Kundakçi
T
,
Kiziltan
E
,
Dogan
O
.
Childhood trauma, dissociation, and psychiatric comorbidity in patients with conversion disorder
.
Am J Psychiatry
.
2004
;
161
(
12
):
2271
6
.
12.
Ogawa
JR
,
Sroufe
LA
,
Weinfield
NS
,
Carlson
EA
,
Egeland
B
.
Development and the fragmented self: longitudinal study of dissociative symptomatology in a nonclinical sample
.
Dev Psychopathol
.
1997
;
9
(
4
):
855
79
.
13.
Brown
RJ
.
Different types of “dissociation” have different psychological mechanisms
.
J Trauma & Dissociation
.
2006
;
7
(
4
):
7
28
.
14.
Holmes
EA
,
Brown
RJ
,
Mansell
W
,
Fearon
RP
,
Hunter
EC
,
Frasquilho
F
et al
.
Are there two qualitatively distinct forms of dissociation? A review and some clinical implications
.
Clin Psychol Rev
.
2005
;
25
:
1
23
.
15.
Nijenhuis
ER
,
Van der Hart
O
.
Dissociation in trauma: a new definition and comparison with previous formulations
.
J Trauma & Dissociation
.
2011
;
12
(
4
):
416
45
.
16.
Cardeña
E
.
The domain of dissociation
. In:
Lynn
SJ
,
Rhue
JW
, editors.
Dissociation: clinical and theoretical perspectives
New York
The Guilford Press
.
1994
. p.
15
31
.
17.
Kozlowska
K
,
Walker
P
,
McLean
L
,
Carrive
P
.
Fear and the defense cascade: clinical implications and management
.
Harv Rev Psychiatry
.
2015
;
23
(
4
):
263
87
.
18.
Butler
C
,
Dorahy
MJ
,
Middleton
W
.
The detachment and compartmentalization inventory (dci): an assessment tool for two potentially distinct forms of dissociation
.
J Trauma & Dissociation
.
2019
;
20
(
5
):
526
47
.
19.
Corrigan
F
,
Hull
A
.
The shadow costs of dissociative identity disorder
.
Br J Psychiatry
.
2022
;
220
(
2
):
98
.
20.
Corrigan
FM
,
Lanius
UF
,
Kaschor
B
.
The defense cascade, traumatic dissociation and the self: a neuroscientific model
. In:
Dorahy
MJ
,
Gold
SN
,
O’Neil
JA
, editors.
Dissociation and the dissociative disorder: past, present, future
New York
Routledge
.
2022
.
21.
Carlson
EA
,
Yates
TM
,
Sroufe
LA
.
Dissociation and the development of the self
. In:
Dell
P
,
O’Neil
JA
, editors.
Dissociation and dissociative disorders: dsm-v and beyond
New York
Routledge
.
2009
. p.
39
52
.
22.
Rodewald
F
,
Dell
PF
,
Wilhelm-Gossling
C
,
Gast
U
.
Are major dissociative disorders characterized by a qualitatively different kind of dissociation
.
J Trauma & Dissociation
.
2011
;
12
(
1
):
9
24
.
23.
Mazzotti
E
,
Farina
B
,
Imperatori
C
,
Mansutti
F
,
Prunetti
E
,
Speranza
AM
et al
.
Is the dissociative experiences scale able to identify detachment and compartmentalization symptoms? Factor structure of the dissociative experiences scale in a large sample of psychiatric and nonpsychiatric subjects
.
Neuropsychiatr Dis Treat
.
2016
;
12
:
1295
302
.
24.
Terpou
BA
,
Densmore
M
,
Théberge
J
,
Frewen
P
,
McKinnon
MC
,
Nicholson
AA
et al
.
The hijacked self: disrupted functional connectivity between the periaqueductal gray and the default mode network in posttraumatic stress disorder using dynamic causal modeling
.
Neuroimage Clin
.
2020
;
27
:
102345
.
25.
Dimitrova
LI
,
Dean
SL
,
Schlumpf
YR
,
Vissia
EM
,
Nijenhuis
ERS
,
Chatzi
V
et al
.
A neurostructural biomarker of dissociative amnesia: a hippocampal study in dissociative identity disorder
.
Psychol Med
.
2021
;
53
(
3
):
805
13
.
26.
Sar
V
.
Parallel-distinct structures of internal world and external reality: disavowing and re-claiming the self-identity in the aftermath of trauma-generated dissociation
.
Front Psychol
.
2017
;
8
:
216
.
27.
Putnam
FW
Dissociation in children and adolescents: a developmental perspective
New York
Guilford press
.
1997
.
28.
Deco
G
,
Tononi
G
,
Boly
M
,
Kringelbach
ML
.
Rethinking segregation and integration: contributions of whole-brain modelling
.
Nat Rev Neurosci
.
2015
;
16
(
7
):
430
9
.
29.
Ohashi
K
,
Anderson
CM
,
Bolger
EA
,
Khan
A
,
McGreenery
CE
,
Teicher
MH
.
Childhood maltreatment is associated with alteration in global network fiber-tract architecture independent of history of depression and anxiety
.
Neuroimage
.
2017
;
150
:
50
9
.
30.
Girgenti
MJ
,
Wang
J
,
Ji
D
,
Cruz
DA
Traumatic Stress Brain Research Group
Stein
MB
et al
.
Transcriptomic organization of the human brain in post-traumatic stress disorder
.
Nat Neurosci
.
2021
;
24
(
1
):
24
33
.
31.
Gordon
EM
,
Lynch
CJ
,
Gratton
C
,
Laumann
TO
,
Gilmore
AW
,
Greene
DJ
et al
.
Three distinct sets of connector hubs integrate human brain function
.
Cell Rep
.
2018
;
24
(
7
):
1687
95.e4
.
32.
Lord
LD
,
Stevner
AB
,
Deco
G
,
Kringelbach
ML
.
Understanding principles of integration and segregation using whole-brain computational connectomics: implications for neuropsychiatric disorders
.
Philos Trans A Math Phys Eng Sci
.
2017
;
375
(
2096
):
20160283
.
33.
Park
HJ
,
Friston
K
.
Structural and functional brain networks: from connections to cognition
.
Science
.
2013
;
342
(
6158
):
1238411
.
34.
Teicher
MH
,
Samson
JA
,
Anderson
CM
,
Ohashi
K
.
The effects of childhood maltreatment on brain structure, function and connectivity
.
Nat Rev Neurosci
.
2016
;
17
(
10
):
652
66
.
35.
Liotti
G
,
Farina
B
.
Painful incoherence: the self in borderline personality disorder
. In:
Kyrios
M
,
Moulding
R
,
Nedeljkovic
M
,
Bhar
SS
,
Doron
G
,
Mikulincer
M
, editors.
The self in understanding and treating psychological disorders
Cambridge
Cambridge University Press
.
2016
. p.
169
78
.
36.
Kearney
BE
,
Lanius
RA
.
The brain-body disconnect: a somatic sensory basis for trauma-related disorders
.
Front Neurosci
.
2022
;
16
:
1015749
.
37.
Dewe
H
,
Watson
DG
,
Kessler
K
,
Braithwaite
JJ
.
The depersonalized brain: new evidence supporting a distinction between depersonalization and derealization from discrete patterns of autonomic suppression observed in a non-clinical sample
.
Conscious Cogn
.
2018
;
63
:
29
46
.
38.
Salami
A
,
Andreu-Perez
J
,
Gillmeister
H
.
Symptoms of depersonalisation/derealisation disorder as measured by brain electrical activity: a systematic review
.
Neurosci Biobehav Rev
.
2020
;
118
:
524
37
.
39.
Gatus
A
,
Jamieson
G
,
Stevenson
B
.
Past and future explanations for depersonalization and derealization disorder: a role for predictive coding
.
Front Hum Neurosci
.
2022
;
16
:
744487
.
40.
Ciaunica
A
,
Seth
A
,
Limanowski
J
,
Hesp
C
,
Friston
KJ
.
I overthink-therefore i am not: an active inference account of altered sense of self and agency in depersonalisation disorder
.
Conscious Cogn
.
2022
;
101
:
103320
.
41.
Frewen
P
,
Hegadoren
K
,
Coupland
NJ
,
Rowe
BH
,
Neufeld
RW
,
Lanius
R
.
Trauma-related altered states of consciousness (trasc) and functional impairment i: prospective study in acutely traumatized persons
.
J Trauma & Dissociation
.
2015
;
16
(
5
):
500
19
.
42.
Lyons-Ruth
K
,
Dutra
L
,
Schuder
MR
,
Bianchi
I
.
From infant attachment disorganization to adult dissociation: relational adaptations or traumatic experiences
.
Psychiatr Clin North Am
.
2006
;
29
(
1
):
63
86
. viii
43.
van der Hart
O
.
Trauma-related dissociation: an analysis of two conflicting models
.
Eur J Trauma Dissoc
.
2021
;
5
(
4
):
100210
.
44.
Dell
PF
,
O’Neil
JA
Dissociation and the dissociative disorders: dsm-v and beyond
New York, NY, US
Routledge/Taylor & Francis Group
.
2009
.
45.
Bromberg
PM
.
Multiple self-states, the relational mind, and dissociation: a psychoanalytic perspective
. In:
Dell
PF
,
O’Neil
JA
, editors.
Dissociation and the dissociative disorders: dsm-v and beyond
New York
Routledge/Taylor & Francis Group
.
2009
. p.
637
52
.
46.
Nijenhuis
ER
.
The metaphor of dissociation: teleological, phenomenological, structural, dynamical
.
Quad Psicol Cog
.
2019
;
44
:
72
105
.
47.
Van der Hart
O
,
Dorahy
M
.
History of the concept of dissociation
. In:
Dell
P
,
O’Neil
JA
, editors.
Dissociation and dissociative disorders: dsm-v and beyond
New York
Routledge
.
2009
. p.
3
26
.
48.
Meares
R
The dissociation model of borderline personality disorder
New York
Norton Professional Books
.
2012
.
49.
American Psychiatric Association
Diagnostic and statistical manual of mental disorders - dsm-5
5th ed
Arlington
American Psychiatric Publishing
.
2013
.
50.
Cavicchioli
M
,
Scalabrini
A
,
Northoff
G
,
Mucci
C
,
Ogliari
A
,
Maffei
C
.
Dissociation and emotion regulation strategies: a meta-analytic review
.
J Psychiatr Res
.
2021
;
143
:
370
87
.
51.
Bassett
DS
,
Sporns
O
.
Network neuroscience
.
Nat Neurosci
.
2017
;
20
(
3
):
353
64
.
52.
Fukushima
M
,
Sporns
O
.
Structural determinants of dynamic fluctuations between segregation and integration on the human connectome
.
Commun Biol
.
2020
;
3
(
1
):
606
.
53.
Cohen
JR
,
D’Esposito
M
.
The segregation and integration of distinct brain networks and their relationship to cognition
.
J Neurosci
.
2016
;
36
(
48
):
12083
94
.
54.
Pessoa
L
.
The entangled brain
.
J Cogn Neurosci
.
2023
;
35
(
3
):
349
60
.
55.
Janet
P
L’automatisme psychologique: essai de psychologie expérimentale sur les formes inférieures de l'activité humaine
Paris
Alcan
.
1889
.
56.
Ferguson
BR
,
Gao
WJ
.
Pv interneurons: critical regulators of e/i balance for prefrontal cortex-dependent behavior and psychiatric disorders
.
Front Neural Circuits
.
2018
;
12
:
37
.
57.
Winnicott
DW
.
Ego integration in child development (1962)
. In:
Winnicott
DW
, editor.
The maturational processes and the facilitating environment
London
Karnac
.
1965
.
58.
Fonagy
P
,
Target
M
.
Attachment and reflective function: their role in self-organization
.
Dev Psychopathol
.
1997
;
9
(
4
):
679
700
.
59.
Scalabrini
A
,
Mucci
C
,
Northoff
G
.
The nested hierarchy of self and its trauma: in search for a synchronic dynamic and topographical re-organization
.
Front Hum Neurosci
.
2022
;
16
:
980353
.
60.
Schimmenti
A
.
The relationship between attachment and dissociation. Theory, research, and clinical implications
. In:
Dorahy
MJ
,
Gold
SN
,
O’Neil
JA
, editors.
Dissociation and the dissociative disorder: past, present, future
New York
Routledge
.
2022
.
61.
Massullo
C
,
De Rossi
E
,
Carbone
GA
,
Imperatori
C
,
Ardito
RB
,
Adenzato
M
et al
.
Child maltreatment, abuse, and neglect: an umbrella review of their prevalence and definitions
.
Clin Neuropsychiatry
.
2023
;
20
(
2
):
72
99
.
62.
U.S. Department of Health & Human Services AfCaF
Administration on children, youth and families, children’s bureau
Child maltreatment 2015
.
2017
. Available from: https://www.acf.hhs.gov/cb/report/child-maltreatment-2015.
63.
McLaughlin
KA
,
Sheridan
MA
,
Nelson
CA
.
Neglect as a violation of species-expectant experience: neurodevelopmental consequences
.
Biol Psychiatry
.
2017
;
82
(
7
):
462
71
.
64.
Liotti
G
.
Conflicts between motivational systems related to attachment trauma: key to understanding the intra-family relationship between abused children and their abusers
.
J Trauma & Dissociation
.
2017
;
18
(
3
):
304
18
.
65.
Isobel
S
,
Goodyear
M
,
Foster
K
.
Psychological trauma in the context of familial relationships: a concept analysis
.
Trauma Violence Abuse
.
2019
;
20
(
4
):
549
59
.
66.
Farina
B
,
Liotti
M
,
Imperatori
C
.
The role of attachment trauma and disintegrative pathogenic processes in the traumatic-dissociative dimension
.
Front Psychol
.
2019
;
10
:
933
.
67.
Cay
M
,
Gonzalez-Heydrich
J
,
Teicher
MH
,
van der Heijden
H
,
Ongur
D
,
Shinn
AK
et al
.
Childhood maltreatment and its role in the development of pain and psychopathology
.
Lancet Child Adolesc Health
.
2022
;
6
(
3
):
195
206
.
68.
Gunnar
M
,
Quevedo
K
.
The neurobiology of stress and development
.
Annu Rev Psychol
.
2007
;
58
:
145
73
.
69.
Weems
CF
,
Russell
JD
,
Neill
EL
,
McCurdy
BH
.
Annual research review: pediatric posttraumatic stress disorder from a neurodevelopmental network perspective
.
J Child Psychol Psychiatry
.
2019
;
60
(
4
):
395
408
.
70.
Carbone
GA
,
Imperatori
C
,
Bersani
FS
,
Massullo
C
,
Orlando
EM
,
Farina
B
.
Dissociative-traumatic dimension and triple network: an eeg functional connectivity study in a sample of university students
.
Psychopathology
.
2022
;
55
(
1
):
28
36
.
71.
Lanius
RA
,
Terpou
BA
,
McKinnon
MC
.
The sense of self in the aftermath of trauma: lessons from the default mode network in posttraumatic stress disorder
.
Eur J Psychotraumatol
.
2020
;
11
(
1
):
1807703
.
72.
Akiki
TJ
,
Averill
CL
,
Wrocklage
KM
,
Scott
JC
,
Averill
LA
,
Schweinsburg
B
et al
.
Default mode network abnormalities in posttraumatic stress disorder: a novel network-restricted topology approach
.
Neuroimage
.
2018
;
176
:
489
98
.
73.
Rifkin-Graboi
A
,
Kong
L
,
Sim
LW
,
Sanmugam
S
,
Broekman
BF
,
Chen
H
et al
.
Maternal sensitivity, infant limbic structure volume and functional connectivity: a preliminary study
.
Transl Psychiatry
.
2015
;
5
(
10
):
e668
.
74.
Adenzato
M
,
Imperatori
C
,
Ardito
RB
,
Valenti
EM
,
Marca
GD
,
D’Ari
S
et al
.
Activating attachment memories affects default mode network in a non-clinical sample with perceived dysfunctional parenting: an eeg functional connectivity study
.
Behav Brain Res
.
2019
;
372
:
112059
.
75.
Krause-Utz
A
,
Frost
R
,
Winter
D
,
Elzinga
BM
.
Dissociation and alterations in brain function and structure: implications for borderline personality disorder
.
Curr Psychiatry Rep
.
2017
;
19
(
1
):
6
.
76.
D’Agostino
A
,
Pepi
R
,
Rossi Monti
M
,
Starcevic
V
.
The feeling of emptiness: a review of a complex subjective experience
.
Harv Rev Psychiatry
.
2020
;
28
(
5
):
287
95
.
77.
Huang
YL
,
Fonagy
P
,
Feigenbaum
J
,
Montague
PR
,
Nolte
T
London Personality and Mood Disorder Research Consortium
.
Multidirectional pathways between attachment, mentalizing, and posttraumatic stress symptomatology in the context of childhood trauma
.
Psychopathology
.
2020
;
53
(
1
):
48
58
.
78.
Luyten
P
,
Campbell
C
,
Fonagy
P
.
Borderline personality disorder, complex trauma, and problems with self and identity: a social-communicative approach
.
J Pers
.
2020
;
88
(
1
):
88
105
.
79.
Lutz
PE
,
Tanti
A
,
Gasecka
A
,
Barnett-Burns
S
,
Kim
JJ
,
Zhou
Y
et al
.
Association of a history of child abuse with impaired myelination in the anterior cingulate cortex: convergent epigenetic, transcriptional, and morphological evidence
.
Am J Psychiatry
.
2017
;
174
(
12
):
1185
94
.
80.
Misaki
M
,
Phillips
R
,
Zotev
V
,
Wong
CK
,
Wurfel
BE
,
Krueger
F
et al
.
Connectome-wide investigation of altered resting-state functional connectivity in war veterans with and without posttraumatic stress disorder
.
Neuroimage Clin
.
2018
;
17
:
285
96
.
81.
Wolf
RC
,
Sambataro
F
,
Vasic
N
,
Schmid
M
,
Thomann
PA
,
Bienentreu
SD
et al
.
Aberrant connectivity of resting-state networks in borderline personality disorder
.
J Psychiatry Neurosci
.
2011
;
36
(
6
):
402
11
.
82.
Farina
B
,
Speranza
AM
,
Dittoni
S
,
Gnoni
V
,
Trentini
C
,
Vergano
CM
et al
.
Memories of attachment hamper eeg cortical connectivity in dissociative patients
.
Eur Arch Psychiatry Clin Neurosci
.
2014
;
264
(
5
):
449
58
.
83.
Orth
L
,
Zweerings
J
,
Ibrahim
CN
,
Neuner
I
,
Sarkheil
P
.
Altered functional connectivity during evaluation of self-relevance in women with borderline personality disorder
.
Neuroimage Clin
.
2020
;
27
:
102324
.
84.
Vai
B
,
Sforzini
L
,
Visintini
R
,
Riberto
M
,
Bulgarelli
C
,
Ghiglino
D
et al
.
Corticolimbic connectivity mediates the relationship between adverse childhood experiences and symptom severity in borderline personality disorder
.
Neuropsychobiology
.
2017
;
76
(
2
):
105
15
.
85.
Young
CB
,
Raz
G
,
Everaerd
D
,
Beckmann
CF
,
Tendolkar
I
,
Hendler
T
et al
.
Dynamic shifts in large-scale brain network balance as a function of arousal
.
J Neurosci
.
2017
;
37
(
2
):
281
90
.
86.
Allen
JG
,
Console
DA
,
Lewis
L
.
Dissociative detachment and memory impairment: reversible amnesia or encoding failure
.
Compr Psychiatry
.
1999
;
40
(
2
):
160
71
.
87.
Cernis
E
,
Freeman
D
,
Ehlers
A
.
Describing the indescribable: a qualitative study of dissociative experiences in psychosis
.
PLoS One
.
2020
;
15
(
2
):
e0229091
.
88.
Vogel
M
,
Krippl
M
,
Frenzel
L
,
Riediger
C
,
Frommer
J
,
Lohmann
C
et al
.
Dissociation and pain-catastrophizing: absorptive detachment as a higher-order factor in control of pain-related fearful anticipations prior to total knee arthroplasty (tka)
.
J Clin Med
.
2019
;
8
(
5
):
697
.
89.
Jay
EL
,
Sierra
M
,
Van den Eynde
F
,
Rothwell
JC
,
David
AS
.
Testing a neurobiological model of depersonalization disorder using repetitive transcranial magnetic stimulation
.
Brain Stimul
.
2014
;
7
(
2
):
252
9
.
90.
Terpou
BA
,
Harricharan
S
,
McKinnon
MC
,
Frewen
P
,
Jetly
R
,
Lanius
RA
.
The effects of trauma on brain and body: a unifying role for the midbrain periaqueductal gray
.
J Neurosci Res
.
2019
;
97
(
9
):
1110
40
.
91.
Lanius
RA
,
Boyd
JE
,
McKinnon
MC
,
Nicholson
AA
,
Frewen
P
,
Vermetten
E
et al
.
A review of the neurobiological basis of trauma-related dissociation and its relation to cannabinoid- and opioid-mediated stress response: a transdiagnostic, translational approach
.
Curr Psychiatry Rep
.
2018
;
20
(
12
):
118
.
92.
Cavicchioli
M
,
Ogliari
A
,
Maffei
C
,
Mucci
C
,
Northoff
G
,
Scalabrini
A
.
Neural responses to emotional stimuli across the dissociative spectrum: common and specific mechanisms
.
Psychiatry Clin Neurosci
.
2023
;
77
(
6
):
315
29
.
93.
Tibubos
AN
,
Grammes
J
,
Beutel
ME
,
Michal
M
,
Schmutzer
G
,
Brähler
E
.
Emotion regulation strategies moderate the relationship of fatigue with depersonalization and derealization symptoms
.
J Affect Disord
.
2018
;
227
:
571
9
.
94.
Ó Laoide
A
,
Egan
J
,
Osborn
K
.
What was once essential, may become detrimental: the mediating role of depersonalization in the relationship between childhood emotional maltreatment and psychological distress in adults
.
J Trauma & Dissociation
.
2018
;
19
(
5
):
514
34
.
95.
Lebois
LAM
,
Ross
DA
,
Kaufman
ML
.
“I am not i”: the neuroscience of dissociative identity disorder
.
Biol Psychiatry
.
2022
;
91
(
3
):
e11
3
.
96.
Amos
J
,
Furber
G
,
Segal
L
.
Understanding maltreating mothers: a synthesis of relational trauma, attachment disorganization, structural dissociation of the personality, and experiential avoidance
.
J Trauma & Dissociation
.
2011
;
12
(
5
):
495
509
.
97.
Linde-Krieger
LB
,
Yates
TM
,
Carlson
EA
.
A developmental pathways model of dissociation
. In:
Dorahy
MJ
,
Gold
SN
,
O’Neil
JA
, editors.
Dissociation and the dissociative disorder: past, present, future
New York
Routledge
.
2022
.
98.
Liotti
G
.
Disorganized/disoriented attachment in the etiology of the dissociative disorders
.
Dissociation
.
1992
;
5
:
196
204
.
99.
Radulovic
J
,
Lee
R
,
Ortony
A
.
State-dependent memory: neurobiological advances and prospects for translation to dissociative amnesia
.
Front Behav Neurosci
.
2018
;
12
:
259
.
100.
Prebble
SC
,
Addis
DR
,
Tippett
LJ
.
Autobiographical memory and sense of self
.
Psychol Bull
.
2013
;
139
(
4
):
815
40
.
101.
Damasio
A
.
Feelings of emotion and the self
.
Ann N Y Acad Sci
.
2003
;
1001
:
253
61
.
102.
Vandekerckhove
M
,
Panksepp
J
.
The flow of anoetic to noetic and autonoetic consciousness: a vision of unknowing (anoetic) and knowing (noetic) consciousness in the remembrance of things past and imagined futures
.
Conscious Cogn
.
2009
;
18
(
4
):
1018
28
.
103.
Bluck
S
,
Liao
HW
.
I was therefore i am: creating self-continuity through remembering our personal past
.
IJRLR
.
2013
;
1
(
1
):
7
12
.
104.
Addis
DR
,
Tippett
LJ
.
The contributions of autobiographical memory to the content and continuity of identity: a social-cognitive neuroscience approach
. In:
Sani
F
, editor.
Self continuity: individual and collective perspectives
New York
Psychology Press
.
2008
. p.
71
84
.
105.
Ryan
TJ
,
Frankland
PW
.
Forgetting as a form of adaptive engram cell plasticity
.
Nat Rev Neurosci
.
2022
;
23
(
3
):
173
86
.
106.
Barron
HC
,
Vogels
TP
,
Behrens
TE
,
Ramaswami
M
.
Inhibitory engrams in perception and memory
.
Proc Natl Acad Sci USA
.
2017
;
114
(
26
):
6666
74
.
107.
Schacter
DL
,
Koutstaal
W
,
Norman
KA
.
Can cognitive neuroscience illuminate the nature of traumatic childhood memories
.
Curr Opin Neurobiol
.
1996
;
6
(
2
):
207
14
.
108.
Peters
ML
,
Uyterlinde
SA
,
Consemulder
J
,
van der Hart
O
.
Apparent amnesia on experimental memory tests in dissociative identity disorder: an exploratory study
.
Conscious Cogn
.
1998
;
7
(
1
):
27
41
.
109.
Moreira
PS
,
Almeida
PR
,
Leite-Almeida
H
,
Sousa
N
,
Costa
P
.
Impact of chronic stress protocols in learning and memory in rodents: systematic review and meta-analysis
.
PLoS One
.
2016
;
11
(
9
):
e0163245
.
110.
Gilboa
A
,
Marlatte
H
.
Neurobiology of schemas and schema-mediated memory
.
Trends Cogn Sci
.
2017
;
21
(
8
):
618
31
.
111.
Henson
RN
,
Greve
A
,
Cooper
E
,
Gregori
M
,
Simons
JS
,
Geerligs
L
et al
.
The effects of hippocampal lesions on mri measures of structural and functional connectivity
.
Hippocampus
.
2016
;
26
(
11
):
1447
63
.
112.
Sala-Llonch
R
,
Junqué
C
,
Arenaza-Urquijo
EM
,
Vidal-Piñeiro
D
,
Valls-Pedret
C
,
Palacios
EM
et al
.
Changes in whole-brain functional networks and memory performance in aging
.
Neurobiol Aging
.
2014
;
35
(
10
):
2193
202
.
113.
Nijenhuis
ER
.
Somatoform dissociation and somatoform dissociative disorders
. In:
Dell
P
,
O’Neil
JO
, editors.
Dissociation and dissociative disorders
New York
Routledge Press
.
2009
. p.
259
75
.
You do not currently have access to this content.