Background/Methods: This paper analyses the psychopathology and differential diagnosis of anxiety disorders and their worldwide prevalence. It focuses particularly on migrant-specific aetiopathogenetic factors and approaches prevalence and important cultural aspects of anxiety disorders in migrants as a narrative empirical review. Results: Transcultural research demonstrates the universal existence of anxiety disorders. However, the cross-cultural comparison of the epidemiological data is complicated and often leads to systematic bias. The described psychopathology varies significantly across cultures, indicating different ways of expressing and experiencing the basic emotion of anxiety. As a result, anxiety disorders manifest themselves differently across cultures, which may affect the diagnostic and therapeutic procedure. Migration is an additional extraordinary stressor playing a substantial role in the development of anxiety disorders. However, despite the high prevalence of anxiety disorders among migrants, a high threshold due to several barriers leads to an underrepresentation of migrants in the utilization of the mental health system. Conclusions: In the transcultural differential diagnosis of anxiety disorders, as among migrants, understanding and openness to other cultures and their standards is essential. Thereby, a migrant-specific treatment approach with a long-term binding of patients in a multimodal and culture-sensitive and -permissive treatment option is of vital importance.

1.
Cannon WB: Bodily Changes in Pain, Hunger, Fear and Rage: An Account of Recent Researches into the Functions of Emotional Excitement. New York, Appleton, 1915.
2.
Endler NS, Kocovski NL: State and trait anxiety revisited. J Anxiety Disord 2001;15:231-245.
3.
Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE: Lifetime prev-alence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005;62:593-602.
4.
Alonso J, Angermeyer MC, Bernert S, Bruffaerts R, Brugha TS, Bryson H, de Girolamo G, Graaf R, Demyttenaere K, Gasquet I, Haro JM, Katz SJ, Kessler RC, Kovess V, Lepine JP, Ormel J, Polidori G, Russo LJ, Vilagut G, Almansa J, Arbabzadeh-Bouchez S, Autonell J, Bernal M, Buist-Bouwman MA, Codony M, Domingo-Salvany A, Ferrer M, Joo SS, Martinez-Alonso M, Matschinger H, Mazzi F, Morgan Z, Morosini P, Palacin C, Romera B, Taub N, Vollebergh WA: Prevalence of mental disorders in Europe: results from the European Study of the Epidemiology of Mental Disorders (ESEMeD) project. Acta Psychiatr Scand Suppl 2004:21-27.
5.
Jacobi F, Wittchen HU, Holting C, Hofler M, Pfister H, Muller N, Lieb R: Prevalence, co-morbidity and correlates of mental disorders in the general population: Results from the German Health Interview and Examination Survey (GHS). Psychol Med 2004;34:597-611.
6.
Dekker J, Peen J, Koelen J, Smit F, Schoevers R: Psychiatric disorders and urbanization in Germany. BMC Public Health 2008;8:17.
7.
Asnaani A, Richey JA, Dimaite R, Hinton DE, Hofmann SG: A cross-ethnic comparison of lifetime prevalence rates of anxiety disorders. J Nerv Ment Dis 2010;198:551-555.
8.
Schwarz E, Birn H: Dental anxiety in Danish and Chinese adults: a cross-cultural perspective. Soc Sci Med 1995;41:123-130.
9.
de Wit MA, Tuinebreijer WC, Dekker J, Beekman AJ, Gorissen WH, Schrier AC, Penninx BW, Komproe IH, Verhoeff AP: Depressive and anxiety disorders in different ethnic groups: a population based study among native Dutch, and Turkish, Moroccan and Surinamese migrants in Amsterdam. Soc Psychiatry Psychiatr Epidemiol 2008;43:905-912.
10.
Lewis-Fernandez R, Hinton DE, Laria AJ, Patterson EH, Hofmann SG, Craske MG, Stein DJ, Asnaani A, Liao B: Culture and the anxiety disorders: recommendations for DSM-V. Depress Anxiety 2010;27:212-229.
11.
Lesch KP, Bengel D, Heils A, Sabol SZ, Greenberg BD, Petri S, Benjamin J, Muller CR, Hamer DH, Murphy DL: Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region. Science 1996;274:1527-1531.
12.
Flint J: Psychiatric genetics: a frightful chromosome. Curr Biol 2001;11:R907-R909.
13.
Hoehn-Saric R, Merchant AF, Keyser ML, Smith VK: Effects of clonidine on anxiety disorders. Arch Gen Psychiatry 1981;38:1278-1282.
14.
Davis M, Rainnie D, Cassell M: Neurotransmission in the rat amygdala related to fear and anxiety. Trends Neurosci 1994;17:208-214.
15.
Bermejo I, Mayninger E, Kriston L, Harter M: Mental disorders in people with migration background compared with German general population. Psychiatr Prax 2010;37:225-232.
16.
Norredam M, Garcia-Lopez A, Keiding N, Krasnik A: Risk of mental disorders in refugees and native Danes: a register-based retrospective cohort study. Soc Psychiatry Psychiatr Epidemiol 2009;44:1023-1029.
17.
Pena JB, Wyman PA, Brown CH, Matthieu MM, Olivares TE, Hartel D, Zayas LH: Immigration generation status and its association with suicide attempts, substance use, and depressive symptoms among latino adolescents in the USA. Prev Sci 2008;9:299-310.
18.
Mirsky J: Mental health implications of migration: a review of mental health community studies on Russian-speaking immigrants in Israel. Soc Psychiatry Psychiatr Epidemiol 2009;44:179-187.
19.
Steiner KH, Johansson SE, Sundquist J, Wandell PE: Self-reported anxiety, sleeping problems and pain among Turkish-born immigrants in Sweden. Ethn Health 2007;12:363-379.
20.
Wittig U, Lindert J, Merbach M, Brahler E: Mental health of patients from different cultures in Germany. Eur Psychiatry 2008;23(suppl 1):28-35.
21.
Bhugra D: Migration and mental health. Acta Psychiatr Scand 2004;109:243-258.
22.
Shrout PE, Canino GJ, Bird HR, Rubio-Stipec M, Bravo M, Burnam MA: Mental health status among Puerto Ricans, Mexican Amer-icans, and non-Hispanic whites. Am J Community Psychol 1992;20:729-752.
23.
Carta MG, Kovess V, Hardoy MC, Morosini P, Murgia S, Carpiniello B: Psychiatric disorders in Sardinian immigrants to Paris: a comparison with Parisians and Sardinians resident in Sardinia. Soc Psychiatry Psychiatr Epidemiol 2002;37:112-117.
24.
Breslau J, Aguilar-Gaxiola S, Borges G, Castilla-Puentes RC, Kendler KS, Medina-Mora ME, Su M, Kessler RC: Mental disorders among English-speaking Mexican immigrants to the US compared to a national sample of Mexicans. Psychiatry Res 2007;151:115-122.
25.
Haasen C, Levit O, Gelbert A, Foroutan N, Norovjav A, Sinaa M, Demiralay C: Relationship between mental distress and acculturation among migrants (in German). Psychiatr Prax 2007;34:339-342.
26.
Demiralay C, Haasen C: Akkulturation; in Machleidt W, Heinz A (eds): Praxis der interkulturellen Psychiatrie und Psychothera-pie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 63-66.
27.
Agorastos A, Ströhle A: Angststörungen; in Machleidt W, Heinz A (eds): Praxis der interkulturellen Psychiatrie und Psychotherapie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 293-306.
28.
Anbesse B, Hanlon C, Alem A, Packer S, Whitley R: Migration and mental health: a study of low-income Ethiopian women working in middle eastern countries. Int J Soc Psychiatry 2009;55:557-568.
29.
Igel U, Brahler E, Grande G: The influence of perceived discrimination on health in migrants. Psychiatr Prax 2010;37:183-190.
30.
Martínez Moneo M, Martínez Larrea A: Migration and psychiatric diseases (in Spanish). An Sist Sanit Navar 2006;29(suppl 1):63-75.
31.
Carta MG, Bernal M, Hardoy MC, Haro-Abad JM: Migration and mental health in Europe (the state of the mental health in Europe working group: appendix 1). Clin Pract Epidemiol Ment Health 2005;1:13.
32.
Agorastos A: Religion und Migration; in Machleidt W, Heinz A (eds): Praxis der in-terkulturellen Psychiatrie und Psychotherapie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 85-91.
33.
Sieben A, Straub J: Migration, Kultur und Identität; in Machleidt W, Heinz A (eds): Praxis der interkulturellen Psychiatrie und Psychotherapie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 43-53.
34.
Brown DR, Eaton WW, Sussman L: Racial differences in prevalence of phobic disorders. J Nerv Ment Dis 1990;178:434-441.
35.
Merbach M, Wittig U, Brahler E: Anxiety and depression by Polish and Vietnamese migrants in Leipzig depending on their adaptation process (in German). Psychother Psychosom Med Psychol 2008;58:146-154.
36.
Momartin S, Steel Z, Coello M, Aroche J, Silove DM, Brooks R: A comparison of the mental health of refugees with temporary versus permanent protection visas. Med J Aust 2006;185:357-361.
37.
Castañeda H: Illegality as risk factor: a survey of unauthorized migrant patients in a Berlin clinic. Soc Sci Med 2009;68:1552-1560.
38.
Lindert J, Ehrenstein OS, Priebe S, Mielck A, Brahler E: Depression and anxiety in labor migrants and refugees: a systematic review and meta-analysis. Soc Sci Med 2009;69:246-257.
39.
Gwynn RC, McQuistion HL, McVeigh KH, Garg RK, Frieden TR, Thorpe LE: Prevalence, diagnosis, and treatment of depression and generalized anxiety disorder in a diverse urban community. Psychiatr Serv 2008;59:641-647.
40.
Malgady RG, Rogler LH: Mental health status among Puerto Ricans, Mexican Americans, and non-Hispanic whites: the case of the misbegotten hypothesis. Am J Community Psychol 1993;21:383-388; discussion 389-395.
41.
Makanjuola RO: ‘Ode ori': a culture-bound disorder with prominent somatic features in Yoruba Nigerian patients. Acta Psychiatr Scand 1987;75:231-236.
42.
Ebigbo PO: A cross-sectional study of somatic complaints of Nigerian females using the Enugu Somatization Scale. Cult Med Psychiatry 1986;10:167-186.
43.
Bhatia MS, Malik SC: Dhat syndrome: a useful diagnostic entity in Indian culture. Br J Psychiatry 1991;159:691-695.
44.
Copeland JRM: Aspects of mental illness in West African students. Soc Psychiatry 1968;3:7-13.
45.
Rubel AJ, O'Nell CW, Collado-Ardon R: Susto: A Folk Illness. Berkeley, University of California Press, 1984.
46.
Bartholomew RE: The social psychology of ‘epidemic' koro. Int J Soc Psychiatry 1994;40:46-60.
47.
Jilek WG: Epidemics of ‘genital shrinking' (koro): historical review and report of a recent outbreak in south China. Curare 1986;9:269-282.
48.
Salmán E, Liebowitz MR, Guarnaccia PJ, Jusino CM, Garfinkel R, Street L, Cárdenas DL, Silvestre J, Fyer AJ, Carrasco JL, Davies SO, Klein DF: Subtypes of ataques de nervios: the influence of coexisting psychiatric diagnosis. Cult Med Psychiatry 1998;22:231-244.
49.
Suzuki K, Takei N, Kawai M, Minabe Y, Mori N: Is taijin kyofusho a culture-bound syndrome? Am J Psychiatry 2003;160:1358.
50.
Norredam M, Nielsen SS, Krasnik A: Migrants' utilization of somatic healthcare services in Europe: a systematic review. Eur J Public Health 2010;20:555-563.
51.
Haasen C, Lambert M, Yagdiran O, Krausz M: Psychiatric disorders among migrants in Germany: prevalence in a psychiatric clinic and implications for services and research. Eur Psychiatry 1997;12:305-310.
52.
Lindert J, Schouler-Ocak M, Heinz A, Priebe S: Mental health, health care utilisation of migrants in Europe. Eur Psychiatry 2008;23(suppl 1):14-20.
53.
Kamperman AM, Komproe IH, de Jong JT: Migrant mental health: a model for indicators of mental health and health care consumption. Health Psychol 2007;26:96-104.
54.
Van der Stuyft P, De Muynck A, Schillemans L, Timmerman C: Migration, acculturation and utilization of primary health care. Soc Sci Med 1989;29:53-60.
55.
Lo HT, Fung KP: Culturally competent psychotherapy. Can J Psychiatry 2003;48:161-170.
56.
Draguns JG, Tanaka-Matsumi J: Assessment of psychopathology across and within cultures: issues and findings. Behav Res Ther 2003;41:755-776.
57.
Tseng WS: Culture and psychotherapy: review and practical guidelines. Transcult Psychiatry 1999;36:131-179.
58.
Seidel R: Interkulturelle Kompetenz; in Machleidt W, Heinz A (eds): Praxis der in-terkulturellen Psychiatrie und Psychotherapie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 161-169.
59.
Abdallah-Steinkopff B: Die Rolle des Drit- ten - Dolmetscher in der Einzel- und Gruppentherapie mit Flüchtlingen. Gruppen-psychother Gruppendynamik 2006;4:280-302.
60.
Kluge U: Sprach- und Kulturmittler im interkulturellen psychotherapeutischen Setting; in Machleidt W, Heinz A (eds): Praxis der interkulturellen Psychiatrie und Psychotherapie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 145-154.
61.
Erim Y, Senf W: Psychotherapie mit Mig-ranten - interkulturelle Aspekte in der Psychotherapie. Psychotherapeut 2002;47:336-346.
62.
Reynolds DK, Kiefer CW: Cultural adaptability as an attribute of therapies: the case of Morita psychotherapy. Cult Med Psychiatry 1977;1:395-412.
63.
Kabat-Zinn J, Massion AO, Kristeller J, Peterson LG, Fletcher KE, Pbert L, Lenderking WR, Santorelli SF: Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders. Am J Psychiatry 1992;149:936-943.
64.
Lee SH, Ahn SC, Lee YJ, Choi TK, Yook KH, Suh SY: Effectiveness of a meditation-based stress management program as an adjunct to pharmacotherapy in patients with anxiety disorder. J Psychosom Res 2007;62:189-195.
65.
Montgomery SA, Sheehan DV, Meoni P, Haudiquet V, Hackett D: Characterization of the longitudinal course of improvement in generalized anxiety disorder during long-term treatment with venlafaxine XR. J Psychiatr Res 2002;36:209-217.
66.
Bandelow B, Zohar J, Hollander E, Kasper S, Möller HJ: World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and posttraumatic stress disorders. World J Biol Psychiatry 2002;3:171-199.
67.
Bielski RJ, Bose A, Chang CC: A double-blind comparison of escitalopram and paroxetine in the long-term treatment of generalized anxiety disorder. Ann Clin Psychiatry 2005;17:65-69.
68.
Stocchi F, Nordera G, Jokinen RH, Lepola UM, Hewett K, Bryson H, Iyengar MK: Efficacy and tolerability of paroxetine for the long-term treatment of generalized anxiety disorder. J Clin Psychiatry 2003;64:250-258.
69.
Yonkers KA, Dyck IR, Warshaw M, Keller MB: Factors predicting the clinical course of generalised anxiety disorder. Br J Psychiatry 2000;176:544-549.
70.
Stein DJ, Versiani M, Hair T, Kumar R: Efficacy of paroxetine for relapse prevention in social anxiety disorder: a 24-week study. Arch Gen Psychiatry 2002;59:1111-1118.
71.
Walker JR, Van Ameringen MA, Swinson R, Bowen RC, Chokka PR, Goldner E, Johnston DC, Lavallie YJ, Nandy S, Pecknold JC, Hadrava V, Lane RM: Prevention of relapse in generalized social phobia: results of a 24-week study in responders to 20 weeks of sertraline treatment. J Clin Psychopharmacol 2000;20:636-644.
72.
Mavissakalian M, Perel JM: Clinical experiments in maintenance and discontinuation of imipramine therapy in panic disorder with agoraphobia. Arch Gen Psychiatry 1992;49:318-323.
73.
Haug TT, Blomhoff S, Hellstrom K, Holme I, Humble M, Madsbu HP, Wold JE: Exposure therapy and sertraline in social phobia: 1-year follow-up of a randomised controlled trial. Br J Psychiatry 2003;182:312-318.
74.
Liebowitz MR, Heimberg RG, Schneier FR, Hope DA, Davies S, Holt CS, Goetz D, Juster HR, Lin SH, Bruch MA, Marshall RD, Klein DF: Cognitive-behavioral group therapy versus phenelzine in social phobia: long-term outcome. Depress Anxiety 1999;10:89-98.
75.
Leavey G, Guvenir T, Haase-Casanovas S, Dein S: Finding help: Turkish-speaking refugees and migrants with a history of psychosis. Transcult Psychiatry 2007;44:258-274.
76.
Bottlender R, Hloucal TM, Priebe S: Gemein-depsychiatrische Versorgung von Migran-ten; in Machleidt W, Heinz A (eds): Praxis der interkulturellen Psychiatrie und Psychotherapie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 517-525.
77.
Koch E, Küchenhoff B, Schouler-Ocak M: Inanspruchnahme psychiatrischer Einrichtungen von psychisch kranken Migranten in Deutschland und der Schweiz; in Machleidt W, Heinz A (eds): Praxis der interkulturellen Psychiatrie und Psychotherapie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 489-498.
78.
Borde T, David M: Ethnizität und In-an-spruchnahme von klinischen Notfallambulanzen; in Machleidt W, Heinz A (eds): Praxis der interkulturellen Psychiatrie und Psychotherapie: Migration und psychische Gesundheit. München, Urban & Fischer, 2010, pp 467-474.
79.
Arikian SR, Gorman JM: A review of the diagnosis, pharmacologic treatment, and economic aspects of anxiety disorders. Prim Care Companion J Clin Psychiatry 2001;3:110-117.
80.
Costa e Silva JA: The public health impact of anxiety disorders: a WHO perspective. Acta Psychiatr Scand Suppl 1998;393:2-5.
81.
World Health Organization: The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines. Geneva, World Health Organization, 1992.
82.
American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), ed 4. Washington, American Psychiatric Association, 1994.
83.
Demyttenaere K, Bruffaerts R, Posada-Villa J, Gasquet I, Kovess V, Lepine JP, Angermeyer MC, Bernert S, de Girolamo G, Morosini P, Polidori G, Kikkawa T, Kawakami N, Ono Y, Takeshima T, Uda H, Karam EG, Fayyad JA, Karam AN, Mneimneh ZN, Medina-Mora ME, Borges G, Lara C, de Graaf R, Ormel J, Gureje O, Shen Y, Huang Y, Zhang M, Alonso J, Haro JM, Vilagut G, Bromet EJ, Gluzman S, Webb C, Kessler RC, Merikangas KR, Anthony JC, Von Korff MR, Wang PS, Brugha TS, Aguilar-Gaxiola S, Lee S, Heeringa S, Pennell BE, Zaslavsky AM, Ustun TB, Chatterji S: Prevalence, severity, and unmet need for treatment of mental disorders in the World Health Organization World Mental Health Surveys. JAMA 2004;291:2581-2590.
84.
Offord DR, Boyle MH, Campbell D, Goering P, Lin E, Wong M, Racine YA: One-year prevalence of psychiatric disorder in Ontarians 15 to 64 years of age. Can J Psychiatry 1996;41:559-563.
85.
Kessler RC, Anthony JC, Blazer DG, Bromet E, Eaton WW, Kendler K, Swartz M, Witt-chen HU, Zhao S: The US National Comorbidity Survey: overview and future directions. Epidemiol Psichiatr Soc 1997;6:4-16.
86.
Kessler RC, Chiu WT, Demler O, Merikangas KR, Walters EE: Prevalence, severity, and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 2005;62:617-627.
87.
Canino GJ, Bird HR, Shrout PE, Rubio-Stipec M, Bravo M, Martinez R, Sesman M, Guevara LM: The prevalence of specific psychiatric disorders in Puerto Rico. Arch Gen Psychiatry 1987;44:727-735.
88.
Andrade L, Walters EE, Gentil V, Laurenti R: Prevalence of ICD-10 mental disorders in a catchment area in the city of Sao Paulo, Brazil. Soc Psychiatry Psychiatr Epidemiol 2002;37:316-325.
89.
Andrews G, Henderson S, Hall W: Prevalence, comorbidity, disability and service utilisation. Overview of the Australian National Mental Health Survey. Br J Psychiatry 2001;178:145-153.
90.
Oakley-Browne MA, Joyce PR, Wells JE, Bushnell JA, Hornblow AR: Christchurch Psychiatric Epidemiology Study, part II: Six month and other period prevalences of specific psychiatric disorders. Aust N Z J Psychiatry 1989;23:327-340.
91.
Líndal E, Stefánsson JG: The lifetime prevalence of anxiety disorders in Iceland as estimated by the US National Institute of Mental Health Diagnostic Interview Schedule. Acta Psychiatr Scand 1993;88:29-34.
92.
Kringlen E, Torgersen S, Cramer V: A Norwegian psychiatric epidemiological study. Am J Psychiatry 2001;158:1091-1098.
93.
Lepine JP, Gasquet I, Kovess V, Arbabza- deh-Bouchez S, Negre-Pages L, Nachbaur G, Gaudin AF: Prevalence and comorbidity of psychiatric disorders in the French general population (in French). Encephale 2005;31:182-194.
94.
Leray E, Camara A, Drapier D, Riou F, Bougeant N, Pelissolo A, Lloyd KR, Bellamy V, Roelandt JL, Millet B: Prevalence, characteristics and comorbidities of anxiety disorders in France: results from the ‘Mental Health in General Population' Survey (MHGP). Eur Psychiatry 2010, E-pub ahead of print.
95.
Bijl RV, Ravelli A, van Zessen G: Prevalence of psychiatric disorder in the general pop-ulation: results of The Netherlands Mental Health Survey and Incidence Study (NEMESIS). Soc Psychiatry Psychiatr Epidemiol 1998;33:587-595.
96.
Wittchen HU, Nelson CB, Lachner G: Prevalence of mental disorders and psychosocial impairments in adolescents and young adults. Psychol Med 1998;28:109-126.
97.
Faravelli C, Salvatori S, Galassi F, Aiazzi L, Drei C, Cabras P: Epidemiology of somatoform disorders: a community survey in Florence. Soc Psychiatry Psychiatr Epidemiol 1997;32:24-29.
98.
Levinson D, Zilber N, Lerner Y, Grinshpoon A, Levav I: Prevalence of mood and anxiety disorders in the community: results from the Israel National Health Survey. Isr J Psychiatry Relat Sci 2007;44:94-103.
99.
Kadri N, Agoub M, El Gnaoui S, Berrada S, Moussaoui D: Prevalence of anxiety disorders: a population-based epidemiological study in metropolitan area of Casablanca, Morocco. Ann Gen Psychiatry 2007;6:6.
100.
Gureje O, Lasebikan VO, Kola L, Makanjuola VA: Lifetime and 12-month prevalence of mental disorders in the Nigerian Survey of Mental Health and Well-Being. Br J Psychiatry 2006;188:465-471.
101.
Stein DJ, Seedat S, Herman A, Moomal H, Heeringa SG, Kessler RC, Williams DR: Lifetime prevalence of psychiatric disorders in South Africa. Br J Psychiatry 2008;192:112-117.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.