... to in the content or advertisements. 2021 Depression Anxiety Psychotropic drugs Cognitive behavioral therapy Clinimetrics Medicine-based evidence Well-being therapy Major depressive disorder and anxiety disorder commonly coexist [ 1‒4 ], being present in up to 25% of general practice patients...

...David Cohen; Alexander Recalt Background and Objective: Methods and justifications for discontinuing psychotropic drugs in randomized controlled trials (RCTs), and RCTs’ acknowledgement of possible withdrawal symptoms following discontinuation, have not been examined systematically, which...

... persistent somatization (n = 18), demoralization (n = 14) and irritable mood (n = 7). Therapeutic strategies included lifestyle modifications (n = 45), explanatory therapy (n = 30), low-dose clonazepam (n = 23) and modifications of existing treatment with psychotropic drugs (n = 16). Conclusions...

...Joanna Moncrieff; David Cohen Theoretical assumptions about how psychotropic drugs ‘work’ are rarely discussed explicitly. In a ‘disease-centred model,’ drugs are believed to work by acting on a disease process. In contrast, in a ‘drug-centred model,’ the characteristic physiological, behavioural...