... have shown only limited positive effects on loneliness. Based on preliminary evidence for impaired oxytocin signaling in trait-like loneliness, the current proof-of-concept study used a randomized, double-blind, placebo-controlled design to probe intranasal oxytocin (OT) as an adjunct to a short-term...

...Kaat Alaerts; Nicky Daniels; Matthijs Moerkerke; Margaux Evenepoel; Tiffany Tang; Stephanie Van der Donck; Viktoria Chubar; Stephan Claes; Jean Steyaert; Bart Boets; Jellina Prinsen Introduction: Intranasal administration of oxytocin presents a promising new approach to reduce disability associated...

... dysfunction in autism spectrum disorder (ASD). Previous trials investigating effects of daily intranasal oxytocin treatment have reported inconsistent results and have not combined it with positive social interaction. However, in two preclinical studies we established that treatment every other day rather...

... of the relative difference between magnitude of sooner-smaller and later-larger ( a ). Under placebo (PLC), patients with social anxiety disorder showed less patient choices (i.e., stronger impulsive preferences) than healthy controls. Intranasal oxytocin (OXT) increased the number of patient choices across...