Background: Previous studies have suggested that childhood eating and weight problems may be risk factors for eating disorders. Robust evidence is still lacking. Aims: To investigate whether childhood eating and weight problems increase the risk of eating disorders in affected women compared to their unaffected sisters. Methods: Women (150) with anorexia (AN) or bulimia nervosa (BN) recruited from clinical and community samples were compared to their unaffected sister closest in age on maternal reports of childhood eating and weight. Results: Women with BN were significantly more overweight at the ages of 5 and 10 (both OR = 2.8, p < 0.01), ate a lot (OR = 1.3, p < 0.01), were less picky (OR = 0.6, p < 0.05) and ate quickly (OR = 2.3, p < 0.05) between the ages of 6 and 10 compared to their healthy sisters. Significantly more women with AN were described as having a higher weight at 6 months (OR = 0.8, p < 0.01) and 1 year (OR = 0.6, p < 0.01) compared to their healthy sisters. Childhood eating was comparable in the women with AN and their unaffected sisters. Conclusions: Traits of childhood overeating were more common in bulimic women compared to their unaffected siblings. Subjects with AN did not differ from their sisters on eating variables. The increased risk of BN due to childhood overweight suggests that prevention strategies for childhood obesity and overweight may therefore be applicable in BN.

Keywords:
Childhood eating, Feeding problems, Eating disorders, Sister pairs, discordant
1.
Jacobi C, Agras WS, Bryson S, Hammer LD: Behavioral validation, precursors and concomitants of picky eating in childhood. J Am Acad Child Adolesc Psychiatry 2003;42:76–84.
2.
Marchi M, Cohen P: Early childhood eating behaviors and adolescent eating disorders. J Am Acad Child Adolesc Psychiatry 1990;29:112–117.
3.
Kotler LA, Cohen P, Davies M, Pine DS, Walsh BT: Longitudinal relationships between childhood, adolescent and adult eating disorders. J Am Acad Child Adolesc Psychiatry 2001;40:1434–1440.
4.
Shoebridge P, Gowers SG: Parental high concern and adolescent-onset anorexia nervosa: a case-control study to investigate direction of causality. Br J Psychiatry 2000;176:132–137.
5.
Mitchell JE, Boutacoff L, Wilson D: Absence of early feeding problems among bulimic women: observations from parental interviews. Am J Orthopsychiatry 1986;56:313–316.
6.
Fairburn CG, Welch SL, Doll HA, Davies BA, O’Connor ME: Risk factors for bulimia nervosa: a community-based case-control study. Arch Gen Psychiatry 1997;54:509–517.
7.
Fairburn G, Doll HA, Welch SL, Hay PJ, Davies BA, O’Connor ME: Risk factors for binge eating disorder: a community-based, case-control study.Arch Gen Psychiatry 1998;55:425–432.
8.
Killen JD, Taylor CB, Hayward C: Pursuit of thinness and onset of eating disorder symptoms in a community sample of adolescent girls: a three-year prospective analysis. Int J Eat Disord 1994;16:227–238.
9.
Patton GC, Johnson-Sabine E, Wood K, Carlin JB, Wolfe R: Abnormal eating attitudes in London schoolgirls – a prospective epidemiological study: outcome at twelve-month follow-up. Psychol Med 1990;20:383–394.
10.
Wichstrom L: Psychological and behavioral factors unpredictive of disordered eating: a prospective study of the general adolescent population in Norway. Int J Eat Disord 2000;28:33–42.
11.
Killen JD, Taylor CB, Hayward C, Haydel KF, Wilson DM, Hammer LD, Kraemer HC, Blair-Greiner A, Strachowski D: Weight concerns influence the development of eating disorders: a 4-year prospective study.J Consult Clin Psychol 1996;64:936–940.
12.
Patton GC, Selzer R, Coffey C, Carlin JB, Wolfe R: Onset of adolescent eating disorders: population-based cohort study over 3 years. BMJ 1999;318:765–768.
13.
American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders. Washington DC, American Psychiatric Association, 1994.
14.
Kaye WH, Lilenfeld LR, Berrettini WH, Strober M, Devlin B, Klump KL, Goldman D, Bulik CM, Halmi KA, Fichter MM, Kaplan A, Woodside DB, Treasure J, Plotnicov KH, Pollice C, Rao R, McConaha CW: A search for susceptibility loci for anorexia nervosa: methods and sample description. Biol Psychiatry 2000;47:794–803.
15.
Keller MB, Lavori PW, Friedman B, Nielsen E, Endicott J, McDonald-Scott P, Andreasen NC: The Longitudinal Interval Follow-up Evaluation: a comprehensive method for assessing outcome in prospective longitudinal studies.Arch Gen Psychiatry 1987;44:540–548.
16.
Fairburn CG, Cooper Z: The eating disorder examination; in Fairburn CG, Wilson GT (eds): Binge Eating. Nature, Assessment and Treatment (ed 12). New York, Guilford Press, 1993, pp 317–331.
17.
Anderluh MB, Tchanturia K, Rabe-Hesketh S, Treasure J: Childhood obsessive-compulsive personality traits in adult women with eating disorders: defining a broader eating disorder phenotype. Am J Psychiatry 2003;160:242–247.
18.
Birch LL, Fisher JO: Mothers’ child feeding practices influence daughters’ eating and weight. Am J Clin Nutr 2000;71:1054–1061.
19.
Baughcum AE, Powers SW, Johnson SB, Chamberlin LA, Deeks CM, Jain A, Whitaker RC: Maternal feeding practices and beliefs and their relationships to overweight in early childhood. J Dev Behav Pediatr 2001;22:391–408.
20.
Dick DM, Johnson JK, Viken RJ, Rose RJ: Testing between-family associations in within-family comparisons.Psychol Sci 2000;11:409–413.
21.
Rastam M: Anorexia nervosa in 51 Swedish adolescents: premorbid problems and comorbidity. J Am Acad Child Adolesc Psychiatry 1992;31:819–829.
22.
Mangweth B, Hausmann A, Danzi C, Walch T, Rupp CI, Biebl W, Hudson J, Pope H: Childhood body focused behaviours and social behaviours as risk factors for eating disorders. Psychother Psychosom 2005;74:247–253.
23.
Karwautz A, Rabe-Hesketh S, Hu X, Zhao J, Sham P, Collier DA, Treasure JL: Individual-specific risk factors for anorexia nervosa: a pilot study using a discordant sister pair design. Psychol Med 2001;31:317–329.
24.
Graber J, Brooks-Gunn J, Paikoff R, Warren MP: Prediction of eating problems: an eight-year study of adolescent girls. Dev Psychology 1994;30:823–834.
25.
Collier DA, Treasure JL: The aetiology of eating disorders. Br J Psychiatry 2004;185:363–365.
26.
Connan F, Stanley S: Biology of appetite and weight regulation; in Treasure J, Schmidt U, van Furth E (eds): Handbook of Eating Disorders. London, Wiley, 2003, pp 63–88.
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2007
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