The endolymphatic duct and sac was histologically studied in 190 normal and diseased temporal bones coming from 100 individuals of all age groups. A number of hitherto unknown morphological details was reported, particularly in the physiologically most active portion, the pars rugosa of the sac. The histological findings in man are in good agreement with the results of experimental studies and indicate an intensive resorptive function of this area. A marked fibrosis of the tunica propria in Menière’s disease evidently interferes with the resorption of the endolymph in this area and could therefore act as predisposing factor for the development of the attacks. The fact that in the great majority of the cases the pars rugosa is located within the bony capsule makes the chances for a successful treatment of Menière’s disease through decompression of the pars intraduralis dubious.

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