... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Paediatric brain tumor Low-grade glioma Pilocytic astrocytoma RAS/mitogen-activated protein kinase pathway...

... and expedited placement of a ventriculoperitoneal shunt. Case Presentation: A two-year-old girl presented with 3 months of progressive gait disturbance and intranuclear ophthalmoplegia. Following craniotomy for removal of 4th ventricular pilocytic astrocytoma and decompression of hydrocephalus, she suffered...

...Abdulaziz Oqalaa Almubarak; Anwar Ulhaq; Abdulmajeed BinDahmash; Essam Al Shail Pilomyxoid astrocytoma (PMA) is a rare brain tumour generally located in the chiasmatic-hypothalamic region. In comparison to pilocytic astrocytoma, PMA has distinct histopathological features, aggressive clinical...

...Karie G. Villanueva; Nolan D. Rea; Mark D. Krieger Introduction: Pilocytic astrocytomas (PA) are a common, benign childhood tumor known for their slow growth rates and excellent prognosis. The aim of our study was to characterize patient, tumor, and imaging-related risk factors for recurrence...

... pilocytic astrocytoma. No HRAS or KRAS gene mutations were noted in the tumor on genetic sequencing. However, glial tumors have been associated with genetic mutations of RAS upregulation, which may imply a common pathway. [email protected] 9 10 2018 21 01 2019 15 3 2019 ©...

... with a pilocytic astrocytoma centered on the optic chiasm, treated with chemotherapy and radiation at 3 years of age. Routine follow-up imaging at 13 years of age revealed the development of a mass in the septum pellucidum, which was subtotally resected endoscopically because of its proximity to the fornices...

...Albert Tu; Aaron Robison; Edward Melamed; Ian Buchanan; Omid Hariri; Harish Babu; Linda Szymanski; Mark Krieger Background/Aims: Pilocytic astrocytomas are common pediatric tumors. Molecular profiles vary with location of origin. Comparisons of proliferation have not been reported. We sought...

... of a gliofibroma occurring in a young adult 10 years after treatment for a childhood pilocytic astrocytoma. Case: A 14-year-old female underwent complete resection of a right lateral ventricle pilocytic astrocytoma confirmed on postoperative magnetic resonance imaging (MRI). At the age of 17, the tumour recurred...

... imaging (MRI) showed a well-defined lesion in the hypothalamic region. The patient underwent resection of the tumor by the transcallosal transfornicial approach. Histopathology was suggestive of pilocytic astrocytoma. After 3 years, the patient presented with low back pain radiating to the right lower...

... documented case of spontaneous regression of a temporal lobe pilocytic astrocytoma in a patient without neurofibromatosis. Conclusion: Spontaneous regression of low-grade gliomas can occur for tumors in a diversity of anatomical locations, at varying ages and in both sexes. This may have implications...

...Salvador C. Somaza; Douglas Kondziolka; Dade Lunsford; John C. Flickinger; David J. Bissonette; A. Leland Albright To examine the role of stereotactic radiosurgery in the adjuvant management of children with growing and unresectable deep-seated pilocytic astrocytomas, we reviewed our experience...

...Mark D. Krieger; Ignacio Gonzalez-Gomez; Michael L. Levy; Gordon McComb Thirty-six cases of pilocytic astrocytomas treated at the Childrens Hospital of Los Angeles from 1984 through 1995 were reviewed. The mean age at initial presentation was 8 years (range 15 months to 14 years). These patients...

...Peter C. Burger Diagnosis, treatment, and prognostication in brain stem astrocytomas have been hindered by the occurrence in the same site of two distinct pathological entities – fibriUary and pilocytic astrocytomas. The small size of the specimens from this region adds an additional confounding...

... exophytic brain stem gliomas (DEBSGs). Between 1983 and 1991, 12 of 51 patients evaluated for the diagnosis of brain stem glioma were found to have DEBSGs emanating from the pons, pontomedulla-ry junction or medulla. Eleven of the 12 patients had classic juvenile pilocytic astrocytomas. Unlike most other...

... and gadolinium enhancement are variable. Pathological confirmation was obtained by open biopsy in 2 patients, a stereotaxic biopsy was performed on 2 children; 2 children were not biopsied. The tumor histology obtained was that of pilocytic astrocytoma. Two patients were treated with radiation therapy...

...Beatrice Jager; Martin U. Schuhmann; Ralf Schober; Rolf-Dieter Kortmann; Juergen Meixensberger Background: Malignant transformation of pilocytic astrocytomas in children is rare and often linked to previous radiotherapy. Methods and Results: We report a patient who underwent subtotal resection...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Midbrain Pilocytic astrocytoma Radiation Brain stem Glioma Treatment of tumors in the brain stem continues to be a challenging and controversial task [ 1, 2...

...Faruk Zorlu; Ugur Selek; Canan Akyuz; Arzu Ozturk; Figen Soylemezoglu; Nejat Akalan We report the case of a 4-year-old girl presenting with spinal and leptomeningeal dissemination following several subtotal resections of cerebellar pilocytic astrocytomas. 31 12 2004 3 03 2005 29 9...

... right optic nerve and optic chiasm, and a cystic lesion in the pineal region that had resulted in obstructive hydrocephalus. An open biopsy of the right optic nerve tumour was performed, and it was histologically identified as a pilocytic astrocytoma. Local irradiation of 50 Gy to the optic pathway...

..., with resulting prognostic information beyond that provided by present histological or molecular criteria. These groups are: (1) well-circumscribed gliomas and (2) infiltrating or ‘diffuse’ gliomas. Among the former discrete group are pilocytic astrocytoma (PA), subependymal giant cell astrocytoma of tuberous...