... brain tumors in children and found consensus favoring conservative management for lesions with stable appearance over time, with biopsy or resection reserved for growing lesions. However, applying these suggestions to intradural spine tumors must also account for differences in growth rates, malignant...

... of only 8–11 months. Summary: While these lesions were previously thought to behave similarly to adult HGG, emerging data have demonstrated that DIPG is a biologically distinct entity from adult HGG frequently driven by mutations in the histone genes H3.3 and H3.1 not found in adult glioma. While biopsy...

... acute hydrocephalus and mild diffuse leptomeningeal enhancement without an identifiable primary lesion. Methods: The hydrocephalus was managed with a ventriculostomy - later replaced by a ventriculoperitoneal shunt after ruling out infection. A dura mater biopsy obtained prior to shunt insertion...

... be overlooked in the differential diagnosis of neurologic findings in a child. We report a case of an apparently healthy child with a highly abnormal brain MRI, in which the diagnosis of PML was not considered until biopsy. 2015 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved...

...Leland Albright This study addresses the role of biopsies in diffuse pediatric brainstem tumors. Biopsies have been advocated to confirm the diagnosis, to determine the tumor histology, to obtain prognostic information and because they can be done with low risk. Biopsies are opposed because diffuse...

...Benoit Pirotte; Serge Goldman; Sacha Salzberg; David Wikler; Philippe David; Arlette Vandesteene; Patrick van Bogaert; Isabelle Salmon; Jacques Brotchi; Marc Levivier Because brain tumors can be histologically heterogeneous, stereotactic brain biopsies (SBB) may lead to inaccurate diagnosis...

...Mark M. Souweidane; David I. Sandberg; Mark H. Bilsky; Philip H. Gutin Twelve patients underwent endoscopic biopsy of a tumor involving the third ventricle. Nine patients had no significant medical history while 3 had a history of cancer. Unique characteristics of each case dictated the optimal...

... in the interventional MR unit were in the pediatric population (mean age 8.3, median 8, range 2–15 years). Procedures included 2 brain biopsies, 5 craniotomies for tumor, 2 thoracic laminectomies for syringomyelia, and placement of a reservoir into a cystic brainstem tumor. The biopsies and reservoir placement were...