Introduction: In the case of tumor resection in the upper cervical spine, a multilevel laminectomy with instrumented fixation is required to prevent kyphotic deformity and myelopathy. Nevertheless, instrumentation of the cervical spine in children under the age of 8 years is challenging due to anatomical considerations and unavailability of specific instrumentation. Case Presentation: We present a case of 3D-printed model-assisted cervical spine instrumentation in a 4-year-old child with post-laminectomy kyphotic decompensation of the cervical spine and spinal cord injury 1 year after medulloblastoma metastasis resection in the upper cervical spine. Due to unavailability of specific instrumentation, 3D virtual planning was used to assess and plan posterior cervical fixation. Fixation with 3.5 mm lateral mass and isthmic screws was suggested and the feasibility of fixation was confirmed “in vitro” in a 3D-printed model preoperatively to reduce the possibility of intraoperative implant-spine mismatch. Intraoperative conditions completely resembled the preoperative plan and 3.5 mm polyaxial screws were successfully used as planned. Postoperatively the child made a complete neurological recovery and 2 years after the instrumented fusion is still disease free with no signs of spinal decompensation. Discussion/Conclusion: Our case shows that posterior cervical fixation with the conventional screw-rod technique in a 4-year-old child is feasible, but we suggest that suitability and positioning of the chosen implants are preoperatively assessed in a printed 3D model. In addition, a printed 3D model offers the possibility to better visualize and sense spinal anatomy “in vivo,” thereby helping screw placement and reducing the chance for intraoperative complications, especially in the absence of intraoperative spinal navigation.

1.
Roussel
MF
,
Hatten
ME
.
Cerebellum development and medulloblastoma
.
Curr Top Dev Biol
.
2011
;
94
:
235
82
. .
2.
Thomas
A
,
Noël
G
.
Medulloblastoma: optimizing care with a multidisciplinary approach
.
J Multidiscip Healthc
.
2019
;
12
:
335
47
. .
3.
Cattell
HS
,
Clark
GL
.
Cervical kyphosis and instability following multiple laminectomies in children
.
J Bone Joint Surg Am
.
1967
;
49
(
4
):
713
20
. .
4.
Uchida
K
,
Nakajima
H
,
Sato
R
,
Yayama
T
,
Mwaka
ES
,
Kobayashi
S
, et al.
Cervical spondylotic myelopathy associated with kyphosis or sagittal sigmoid alignment: outcome after anterior or posterior decompression
.
J Neurosurg Spine
.
2009
;
11
(
5
):
521
8
. .
5.
Mendenhall
S
,
Mobasser
D
,
Relyea
K
,
Jea
A
.
Spinal instrumentation in infants, children, and adolescents: a review
.
J Neurosurg Pediatr
.
2019
;
23
(
1
):
1
15
. .
6.
Tan
LA
,
Yerneni
K
,
Tuchman
A
,
Li
XJ
,
Cerpa
M
,
Lehman
RA
, et al.
Utilization of the 3D-printed spine model for freehand pedicle screw placement in complex spinal deformity correction
.
J Spine Surg
.
2018
;
4
(
2
):
319
27
. .
7.
Karlin
L
,
Weinstock
P
,
Hedequist
D
,
Prabhu
SP
.
The surgical treatment of spinal deformity in children with myelomeningocele: the role of personalized three-dimensional printed models
.
J Pediatr Orthop B
.
2017
;
26
(
4
):
375
82
. .
8.
Lastikka
M
,
Aarnio
J
,
Helenius
I
.
Instrumented cervical spinal fusions in children: indications and outcomes
.
J Child Orthop
.
2017
;
11
(
6
):
419
27
. .
9.
Anderson
RC
,
Ragel
BT
,
Mocco
J
,
Bohman
LE
,
Brockmeyer
DL
.
Selection of a rigid internal fixation construct for stabilization at the craniovertebral junction in pediatric patients
.
J Neurosurg
.
2007
;
107
(
1 Suppl
):
36
42
. .
10.
Toyama
Y
,
Matsumoto
M
,
Chiba
K
,
Asazuma
T
,
Suzuki
N
,
Fujimura
Y
, et al.
Realignment of postoperative cervical kyphosis in children by vertebral remodeling
.
Spine
.
1994
;
19
(
22
):
2565
70
. .
11.
Sekhon
LH
.
Posterior cervical lateral mass screw fixation: analysis of 1026 consecutive screws in 143 patients
.
J Spinal Disord Tech
.
2005
;
18
(
4
):
297
303
. .
12.
Wilson
CL
,
Ness
KK
.
Bone mineral density deficits and fractures in survivors of childhood cancer
.
Curr Osteoporos Rep
.
2013 Dec
;
11
(
4
):
329
37
. .
13.
Olshan
JS
,
Gubernick
J
,
Packer
RJ
,
D’Angio
GJ
,
Goldwein
JW
,
Willi
SM
, et al.
The effects of adjuvant chemotherapy on growth in children with medulloblastoma
.
Cancer
.
1992
;
70
(
7
):
2013
7
. .
14.
Gurney
JG
,
Ness
KK
,
Stovall
M
,
Wolden
S
,
Punyko
JA
,
Neglia
JP
, et al.
Final height and body mass index among adult survivors of childhood brain cancer: childhood cancer survivor study
.
J Clin Endocrinol Metab
.
2003
;
88
(
10
):
4731
9
. .
15.
Gawade
PL
,
Hudson
MM
,
Kaste
SC
,
Neglia
JP
,
Wasilewski-Masker
K
,
Constine
LS
, et al.
A systematic review of selected musculoskeletal late effects in survivors of childhood cancer
.
Curr Pediatr Rev
.
2014
;
10
(
4
):
249
62
.
16.
Millard
NE
,
De Braganca
KC
.
Medulloblastoma
.
J Child Neurol
.
2016
;
31
(
12
):
1341
53
. .
17.
Coote
JD
,
Nguyen
T
,
Tholen
K
,
Stewart
C
,
Verter
E
,
McGee
J
, et al.
Three-dimensional printed patient models for complex pediatric spinal surgery
.
Ochsner J
.
2019
;
19
(
1
):
49
53
. .
18.
Garg
B
,
Mehta
N
.
Current status of 3D printing in spine surgery
.
J Clin Orthop Trauma
.
2018 Jul–Sep
;
9
(
3
):
218
25
. .
19.
Salazar
D
,
Huff
TJ
,
Cramer
J
,
Wong
L
,
Linke
G
,
Zuniga
J
.
Use of a three-dimensional printed anatomical model for tumor management in a pediatric patient
.
SAGE Open Med Case Rep
.
2020
;
8
:
2050313X20927600
. .
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