Ewing's sarcoma (ES) is a primary malignant tumor of the mesenchymal tissue of bone in children and young adults. Central nervous system metastases of ES are rarely seen. In this paper, we report a case of ES that progressed with dural metastases after spontaneous intracerebral hemorrhage.

Ludwig JA: Ewing sarcoma: historical perspectives, current state-of-the-art, and opportunities for targeted therapy in the future. Curr Opin Oncol 2008;20:412-418.
Postovsky S, Ash S, Ramu IN, Yaniv Y, Zaizov R, Futerman B, Elhasid R, Ben Barak A, Halil A, Ben Arush MW: Central nervous system involvement in children with sarcoma. Oncology 2003;65:118-124.
Kleinschmidt-DeMasters BK: Dural metastases: a retrospective surgical and autopsy series. Arch Pathol Lab Med 2001;125:880-887.
Laigle-Donadey F, Taillibert S, Mokhtari K, Hildebrand J, Delattre J-Y: Dural metastases. J Neurooncol 2005;75:57-61.
Nayak L, Abrey LE, Iwamoto FM: Intracranial dural metastases. Cancer 2009;115:1947-1953.
Kim EY, Lee S-K, Kim DJ, Kim J, Lee K-S, Jung W, Kim DI: Intracranial dural metastasis of Ewing's sarcoma: a case report. Korean J Radiol 2008;9:76-79.
Singleton SD, Koerner CE: Lenticular lesions: not always an epidural hematoma. Pediatr Emerg Care 2001;17:252-254.
Bunyaratavej K, Khaoroptham S, Phonprasert C, Tanboon J, Shuangshoti S: Primary intracranial peripheral primitive neuroectodermal tumor/Ewing's sarcoma presenting with acute intracerebral hemorrhage. Clin Neuropathol 2004;24:184-190.
Li W-Y, Brock P, Saunders DE: Imaging characteristics of primary cranial Ewing sarcoma. Pediatr Radiol 2005;35:612-618.
Pekala JS, Gururangan S, Provenzale JM, Mukundan S: Central nervous system extraosseous Ewing sarcoma: radiologic manifestations of this newly defined pathologic entity. Am J Neuroradiol 2006;27:580-583.
Aslam E, Imran M, Faridi NM: Bilateral parietal extradural metastatic Ewing's sarcoma simulating acute epidural hematoma. J Coll Physicians Surg Pak 2006;16:543-544.
Kalcioğlu MT, Oncel S, Miman MC, Erdem T, Mizrak B: A case of Ewing's sarcoma in the mandible and the skull base. Kulak Burun Bogaz Ihtis Derg 2003;11:144-147.
Olivi A, Donehower RC, Mann RB, Brem H: Solitary, isolated metastasis from Ewing's sarcoma to the brain: case report. Surg Neurol 1991;35:239-243.
Yamashita Y, Kumabe T, Kobayashi T, Abiko H, Seki H, Yoshimoto T: Ewing's sarcoma at the occipital bone presenting as acute epidural hematoma: a case report (in Japanese). No Shinkei Geka 1997;25:567-571.
Navarro R, Laguna A, de Torres C, Cigudosa JC, Suñol M, Cruz O, Mora J: Primary Ewing sarcoma of the tentorium presenting with intracranial hemorrhage in a child. J Neurosurg 2007;107(suppl 5):411-415.
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