Extraventricular neurocytomas mimic central neurocytomas histologically but are located outside the lateral and/or third ventricles. Pontine neurocytomas represent an extremely rare subset of extraventricular neurocytomas, and reports are limited to 2 adults followed under 28 months. The authors present the case of a 14-year-old boy who initially underwent near-total resection of a pontine extraventricular neurocytoma. One-year postoperative surveillance imaging revealed a small, local recurrence treated with intensity-modulated radiation therapy. This case details the diagnosis and management of the first reported pontine extraventricular neurocytoma in a child with 4.5-year follow-up data.

1.
Figarella-Branger D, Soylemezoglu F, Burger P: Central neurotyomas and extraventricular neurocytomas; in Louis D, Ohgake H, Wiestler O, Cavenee W (eds): WHO Classification of Tumours of the Central Nervous System. Lyon, Participe Present, 2007.
2.
Hassoun J, Soylemezoglu F, Gambarelli D, Figarella-Branger D, von Ammon K, Kleihues P: Central neurocytoma: a synopsis of clinical and histological features. Brain Pathol 1993;3:297-306.
3.
Soontornniyomkij V, Schelper RI: Pontine neurocytoma. J Clin Pathol 1996;49:764-765.
4.
Swinson BM, Friedman WA, Yachnis AT: Pontine atypical neurocytoma: case report. Neurosurgery 2006;58:E990, discussion.
5.
Garber ST, Brockmeyer DL: A rare case of a pediatric extraventricular neurocytoma: case report and review of the literature. Childs Nerv Syst 2012;28:321-326.
6.
Giangaspero F, Cenacchi G, Losi L, Cerasoli S, Bisceglia M, Burger PC: Extraventricular neoplasms with neurocytoma features: a clinicopathological study of 11 cases. Am J Surg Pathol 1997;21:206-212.
7.
Limaiem F, Bellil S, Chelly I, Mekni A, Bellil K, Jemel H, Haouet S, Zitouna M, Kchir N: Extraventricular neurocytoma in a child mimicking oligodendroglioma: a diagnostic pitfall. Pathologica 2009;101:105-107.
8.
Makhdoomi R, Malik NK, Wani A, Bhat S, Baba K: Extraventricular neurocytoma of the vermis in a child. J Clin Neurosci 2010;17:1469-1471.
9.
Mpairamidis E, Alexiou GA, Stefanaki K, Sfakianos G, Prodromou N: Extraventricular neurocytoma in a child: case report and review of the literature. J Child Neurol 2009;24:491-494.
10.
Raja AI, Yeaney GA, Jakacki RI, Hamilton RL, Pollack IF: Extraventricular neurocytoma in neurofibromatosis type 1: case report. J Neurosurg Pediatr 2008;2:63-67.
11.
Singh A, Chand K, Singh H, Sarkar C, Sharma MC: Atypical neurocytoma of the spinal cord in a young child. Childs Nerv Syst 2007;23:207-211.
12.
Yang GF, Wu SY, Zhang LJ, Lu GM, Tian W, Shah K: Imaging findings of extraventricular neurocytoma: report of 3 cases and review of the literature. AJNR Am J Neuroradiol 2009;30:581-585.
13.
Choudhari KA, Kaliaperumal C, Jain A, Sarkar C, Soo MY, Rades D, Singh J: Central neurocytoma: a multi-disciplinary review. Br J Neurosurg 2009;23:585-595.
14.
Rades D, Fehlauer F: Treatment options for central neurocytoma. Neurology 2002;59:1268-1270.
15.
Rades D, Fehlauer F, Lamszus K, Schild SE, Hagel C, Westphal M, Alberti W: Well-differentiated neurocytoma: what is the best available treatment? Neuro Oncol 2005;7:77-83.
16.
Rades D, Schild SE: Treatment recommendations for the various subgroups of neurocytomas. J Neurooncol 2006;77:305-309.
17.
Maiuri F, Spaziante R, De Caro ML, Cappabianca P, Giamundo A, Iaconetta G: Central neurocytoma: clinico-pathological study of 5 cases and review of the literature. Clin Neurol Neurosurg 1995;97:219-228.
18.
Schild SE, Scheithauer BW, Haddock MG, Schiff D, Burger PC, Wong WW, Lyons MK: Central neurocytomas. Cancer 1997;79:790-795.
19.
Yasargil MG, von Ammon K, von Deimling A, Valavanis A, Wichmann W, Wiestler OD: Central neurocytoma: histopathological variants and therapeutic approaches. J Neurosurg 1992;76:32-37.
20.
Rades D, Schild SE: Is 50 Gy sufficient to achieve long-term local control after incomplete resection of typical neurocytomas? Strahlenther Onkol 2006;182:415-418.
21.
Rades D, Schild SE: Value of postoperative stereotactic radiosurgery and conventional radiotherapy for incompletely resected typical neurocytomas. Cancer 2006;106:1140-1143.
22.
Brat DJ, Scheithauer BW, Eberhart CG, Burger PC: Extraventricular neurocytomas: pathologic features and clinical outcome. Am J Surg Pathol 2001;25:1252-1260.
23.
Funato H, Inoshita N, Okeda R, Yamamoto S, Aoyagi M: Cystic ganglioneurocytoma outside the ventricular region. Acta Neuropathol 1997;94:95-98.
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