The risk of dengue is increasing due to population migration. It is the most important arboviral infection in the world, with an estimated 100 million cases per year and 2.5 billion people at risk. Generally recovery is the rule, and hemorrhagic complications causing encephalopathy are rare but fatal. We report an unusual case of hemorrhagic encephalopathy in a child with dengue hemorrhagic fever occurring during convalescence who made a successful recovery following surgery.

1.
Solomon T, Dung NM, Vaughn DW, et al: Neurological manifestations of dengue infection. Lancet 2000;355:1053–1059.
2.
World Health Organization: Dengue Hemorrhagic Fever. Diagnosis, Treatment, Prevention, and Control, ed 2. Geneva, World Health Organization, 1997, pp 1–84.
3.
Kautner I, Robinson MJ, Kuhnle U: Dengue virus infection: epidemiology, pathogenesis, clinical presentation, diagnosis, and prevention. J Pediatr 1997;131:516–524.
4.
Rothman AL, Ennis FA: Immunopathogenesis of Dengue hemorrhagic fever. Virology 1999;257:1–6.
5.
Jensenius M, Berild D, Ormaasen V, et al: Fatal subarachnoidal haemorrhage in a Norwegian traveler with dengue virus infection. Scand J Infect Dis 2007;39:272–274.
6.
Dar L, Gupta E, Narang P, Broor S: Cocirculation of dengue serotypes, Delhi, India, 2003. Emerg Infect Dis 2006;12:352–353.
7.
Gupta E, Dar L, Kapoor G, Broor S: The changing epidemiology of dengue in Delhi, India. Virol J 2006;3:92.
8.
Wills BA, Nguyen MD, Ha TL, et al: Comparison of three fluid solutions for resuscitation in dengue shock syndrome. N Engl J Med 2005;353:87–88.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.