Abstract
This is a report of a prenatal sonographic diagnosis of a lateral ventricle choroid plexus papilloma in an in vitro fertilization (IVF)-induced pregnancy of a 40-year-old woman. The baby was delivered at 35 weeks of gestation and surgery was performed 5 days later with a good outcome. Several cases of malignancies associated with IVF are reported in the literature. To the best of the authors’ knowledge, this is the first report of a prenatal diagnosis of choroid plexus papilloma in an IVF-induced pregnancy. The authors also review other cases of choroid plexus papilloma diagnosed prenatally by ultrasound. The theoretical association between IVF and neoplasia is also considered.
References
1.
Lena G, Genitori L, Molina J, Legatte JR, Choux M: Choroid plexus tumours in children. Review of 24 cases. Acta Neurochir (Wien) 1990;106:68–72.
2.
Radkowski MA, Naidich TP, Tomita T, Byrd SE, McLone DG: Neonatal brain tumors: CT and MR findings. J Comput Assist Tomogr 1988;12:10–20.
3.
White L, Giri N, Vowels MR, Lancaster PA: Neuroectodermal tumours in children born after assisted conception (letter; see comments). Lancet 1990;336:1577.
4.
Toren A, Sharon N, Mandel M, Neumann Y, Kenet G, Kaplinsky C, Dor J, Rechavi G: Two embryonal cancers after in vitro fertilization. Cancer 1995;76:2372–2374.
5.
Rizk T, Nabbout R, Koussa S, Akatcherian C: Congenital brain tumor in a neonate conceived by in vitro fertilization. Childs Nerv Syst 2000;16:501–502.
6.
Kobayashi N, Matsui I, Tanimura M, Nagahara N, Akatsuka J, Hirayama T, Sato K: Childhood neuroectodermal tumours and malignant lymphoma after maternal ovulation induction. Lancet 1991;338:955.
7.
Melamed I, Bujanover Y, Hammer J, Spirer Z: Hepatoblastoma in an infant born to a mother after hormonal treatment for sterility. N Engl J Med 1982;307:820.
8.
Doyle P, Bunch KJ, Beral V, Draper GJ: Cancer incidence in children conceived with assisted reproduction technology. Lancet 1998;352:452–453.
9.
Bruinsma F, Venn A, Lancaster P, Speirs A, Healy D: Incidence of cancer in children born after in-vitro fertilization. Hum Reprod 2000;15:604–607.
10.
Lerner-Geva L, Toren A, Chetrit A, Modan B, Mandel M, Rechavi G, Dor J: The risk for cancer among children of women who underwent in vitro fertilization. Cancer 2000;88:2845–2847.
11.
Bergh T, Ericson A, Hillensjo T, Nygren KG, Wennerholm UB: Deliveries and children born after in-vitro fertilisation in Sweden 1982–95:A retrospective cohort study. Lancet 1999;354:1579–1585.
12.
Klip H, Burger CW, de Kraker J, van Leeuwen FE: Risk of cancer in the offspring of women who underwent ovarian stimulation for IVF. Hum Reprod 2001;16:2451–2458.
13.
Adra AM, Mejides AA, Salman FA, Landy HJ, Helfgott AW: Prenatal sonographic diagnosis of a third ventricle choroid plexus papilloma. Prenat Diagn 1994;14:865–867.
14.
Sherer DM, Onyeije CI: Prenatal ultrasonographic diagnosis of fetal intracranial tumors: A review. Am J Perinatol 1998;15:319–328.
15.
Pilu G, De Palma L, Romero R, Bovicelli L, Hobbins JC: The fetal subarachnoid cisterns: An ultrasound study with report of a case of congenital communicating hydrocephalus. J Ultrasound Med 1986;5:365–372.
16.
Romano F, Bratta FG, Caruso G, Naro ED, Serio R, Resta M, Loizzi P: Prenatal diagnosis of choroid plexus papillomas of the lateral ventricle. A report of two cases. Prenat Diagn 1996;16:567–571.
17.
Knierim DS: Choroid plexus tumors in infants. Pediatr Neurosurg 1990;16:276–280.
18.
Hack M, Brish M, Serr DM, Insler V, Lunenfeld B: Outcome of pregnancy after induced ovulation. Follow-up of pregnancies and children born after gonadotropin therapy. JAMA 1970;211:791–797.
19.
Lancaster PA: Congenital malformations after in-vitro fertilisation. Lancet 1987;ii:1392–1393.
20.
Rossing MA, Daling JR, Weiss NS, Moore DE, Self SG: Ovarian tumors in a cohort of infertile women. N Engl J Med 1994;331:771–776.
21.
Venn A, Watson L, Bruinsma F, Giles G, Healy D: Risk of cancer after use of fertility drugs with in-vitro fertilisation. Lancet 1999;354:1586–1590.
© 2002 S. Karger AG, Basel
2002
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