We report the case of a 15-year-old girl with amenorrhea and a several-week history of headache. After the diagnosis of membranous obstruction of the foramen of Magendie suggested by MRI, suboccipital craniotomy for removal of the membrane was carried out. The patient made an excellent postoperative recovery, and postoperative phase-contrast MRI demonstrated patent cerebrospinal fluid (CSF) pathways at the level of the foramina of Magendie and Luschka. We believe that this case is of interest because of the unequivocal evidence on MRI studies of the occlusion of the foramen of Magendie preoperatively, and because of the dramatic postoperative MRI findings demonstrating the effectiveness of the surgical procedure both in terms of ventricular size and CSF flow characterization.

Keywords:
Obstructive hydrocephalus, Foramen of Magendie, Phase-contrast MRI
1.
Harrison HR, Reynolds AF: Trapped fourth ventricle in coccidiodal meningitis. Surg Neurol 1982;17:197–199.
2.
Holland HC, Graham WL: Congenital atresia of the foramina of Luschka and Magendie with hydrocephalus. J Neurosurg 1958;15:688–694.
3.
Hashish H, Guenot M, Mertens P, Sindou M: Chronic hydrocephalus in an adult due to congenital membranous occlusion of the apertura mediana ventriculi quartii (foramen of Magendie). Report of two cases and review of the literature (in French). Neurochirurgie 1999;45:232–236.
4.
Rifkinson-Mann S, Sachdev VP, Huang YP: Congenital fourth ventricular midline outlet obstruction. J Neurosurg 1987;67:595–599.
5.
Caporal R, Segresta JM, Dorf G: Endocrine expressions of hydrocephalus. A case of primary amenorrhoea revealing a stenosis of the foramen of Magendie. Acta Endocrinol (Copenh) 1983;102:161–166.
6.
Mohanty A, Anandh B, Kolluri VR, Praharaj SS: Neuroendoscopic third ventriculostomy in the management of fourth ventricular outlet obstruction. Minim Invasive Neurosurg 1999;42:18–21.
7.
Mracek Z: Congenital atresia of the foramen of Magendie, so-called Dandy-Walker syndrome. Mod Probl Paediatr 1977;18:125–127.
8.
Yoshioka S, Matsukado Y, Uemura S, Nagahiro S, Ootsuka T, Yadomi C: Hydrocephalus due to membranous obstruction of the fourth ventricle aperture (in Japanese). No Shinkei Geka 1985;13:1135–1139.
© 2001 S. Karger AG, Basel
2001
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