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Keywords: Tissue factor
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Pathophysiology of Haemostasis and Thrombosis (1993) 23 (Suppl. 1): 103–106.
Published Online: 28 April 2009
...Ulrich Abildgaard Tissue factor pathway inhibitor (TFPI) is the factor Xa (FXa)-dependent coagulation inhibitor. TFPI is released to the blood after injection of heparin or low molecular weight heparin (LMWH). The post-heparin anticoagulant effect is caused by this release of TFPI. Free TFPI has...
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Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 40–44.
Published Online: 28 April 2009
...Lars C. Petersen; Egon Persson Binding of Ca 2+ to factor VIla is required for its binding to phospholipids, tissue factor, and for obtaining full amidolytic activity. This presentation describes various binding studies performed with recombinant factor VIla and fragments hereof in order...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 6–11.
Published Online: 28 April 2009
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Monocyte Macrophage Tissue factor Factor V/Va Prothrombinase...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 12–16.
Published Online: 28 April 2009
... in hemostasis. Factor Xa activated on a tissue factor (TF)-bearing cell is not equivalent to factor Xa activated on a platelet surface. Factor IX and factor VIII are required for hemostasis because they combine to generate factor Xa on the platelet surface. Factor X activation by factor VIIa/TF does...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 17–19.
Published Online: 28 April 2009
...Nigel Mackman Tissue factor (TF) is inducibly expressed within the vasculature by monocytes and endothelial cells. Transcriptional activation of the TF gene in these two cell types by bacterial lipopolysaccharide (LPS) or cytokines appears to be regulated by a common mechanism. Functional studies...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 66–71.
Published Online: 28 April 2009
... for heart disease. However, FVII circulates as the inert zymogen (FVII), the active enzyme (FVIIa), and possibly other forms as well, obscuring the relationship between any specific form of this enzyme and risk of thrombotic disease. New assay techniques based on soluble mutant tissue factor now permit...
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Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 25–30.
Published Online: 28 April 2009
...Eric Camerer; Hans Prydz Tissue factor is both a trigger of blood coagulation and a true receptor inducing an intracellular signal upon binding of its ligand factor VII to its extracellular parts. When induced in endothelial cells more than 75% of tissue factor antigen was found on the apical side...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 92–95.
Published Online: 28 April 2009
...Elaine Gray; Stephen Thomas; Yogesh Mistry; Stephen Poole The effect of inhibitors of cytokine release and plasma coagulation on lipopolysaccharide (LPS)-indueced tissue factor and interleukin-6 (IL-6) was investigated. Dexamethasone, an inhibitor of cytokine production, inhibited LPS-induced...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 1–5.
Published Online: 28 April 2009
...Vijaya Mohan Rao; Samuel I. Rapaport Binding of factor VII to tissue factor (TF) present on or released from cells initiates TF-dependent coagulation in vivo. Earlier data obtained with relipidated TF suspensions led to the hypothesis that all factor VII bound to limiting TF sites exposed after...