... with thrombophilia, and many PCR-based methods have been described for detecting these variations. However, the genomic DNA extraction is still a rate-limiting and time-consuming step in the PCR process. In an attempt to accelerate this procedure and make it suitable for routine laboratory, we report a single...

...M.M. Samama; D. Simon; M.H. Horellou; M. Trossaërt; I. Elalamy; J. Conard The diagnostic strategies and clinical characteristics of thrombophilia associated with heterozygous or homozygous factor V Leiden mutation have been determined according to the literature and to a personal study in 51...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Hypercoagulable States Thrombophilia DDimer, F1+2 Haemostasis 1996; 26 (Suppl 4): 1-8 MECHANISMS, MARKERS AND MANAGEMENT OF HYPERCOAGULABLE STATES Pier Mannuccio Mannuci Armando...

..., Belgium Identification of Two Different Mutations Causing Protein S Deficiency in Two Unrelated Belgian Families Using a Nonisotopic Scanning and Sequencing Method Key Words PROS1 DNA Thrombotic disease Thrombophilia Abstract Hereditary protein S deficiency is a risk factor for developing recurrent venous...

...E. Briët; L. Engesser; E.J.P. Brommer The syndrome of the hereditary tendency to venous thrombosis or thrombophilia has been recognized only after the discovery of regulatory mechanisms of the haemostatic system. At present, several distinct defects are known as causes of this syndrome: anti...

...Netanel Horowitz; Benjamin Brenner Inherited and acquired thrombophilia are well-known risk factors for venous thromboembolism. The incidence of thrombotic events in cancer patients is increased compared to normal population. Data on inherited thrombophilia and cancer is limited. Most studies...

... to in the content or advertisements. Complete splenic infarction Hirschsprung’s disease Thrombophilia Thrombosis Case Report Pathophysiol Haemost Thromb 2007 08;36:102 104 DOI: 10.1159/000173730 Received: September 6, 2007 Accepted after revision: February 6, 2008 Acute Complete Splenic Infarction...

... Congenital risk factors Acquired risk factors Thrombophilia Abstract Long-term incidence of recurrent venous thromboembolism (VTE) in patients younger than 50 years, not affected by a malignancy or chronic diseases, are poorly characterized. After the initial episode of VTE and cessation of oral...

...Jacqueline Conard; Marie-Hélène Horellou; Meyer-Michel Samama Hereditary thrombophilia increases the risk of thrombosis during pregnancy and postpartum. The recommendations resulting from the Fifth American College of Chest Physicians (ACCP) Consensus Conference on Antithrombotic Therapy were...

... occurring following delivery. Risk factors for deep vein thrombosis have been identified and include age >35 years, operative delivery (particularly emergency Caesarean section), obesity and a personal or family history of thrombosis or thrombophilia. These risk factors should be used to guide...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Thrombophilia Loss-of-function mutation Gain-of-function mutation Procoagulant factors Inhibitors Main Paper...

... or prothrombin nt G20210A SNPs. The Human Genome Project will soon accelerate discovery of new SNPs that are risk factors for venous thrombosis. Statin Lipoprotein Lipid Thrombosis Thrombophilia Protein C APC resistance 17 11 2004 Main Paper Haemostasis 2000;30(suppl 2):26 33 Causes...

..., instructions or products referred to in the content or advertisements. Inflammatory bowel disease Platelets Thrombophilia Coagulation IL-6 Pathophysiology ofHaemostasis andThrombosis Original Paper Pathophysiol Haemost Thromb 2002;32:92 96 Received: January 2, 2002 Accepted in revised form: April...

... of the MTHFR 677 TT genotype was slightly higher among cases (14.3%) than controls (11.7%), conferring a borderline degree of heightened risk [pooled OR (OR p ) 1.2, 95% confidence interval (CI) 1.1–1.4]. After excluding cases with a classic thrombophilia factor, the pooled prevalence rates of the MTHFR 677 TT...