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Keywords: Thrombomodulin
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Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 4): 227–232.
Published Online: 28 April 2009
...H. Ireland; K. Kyriakoulis; G. Kunz; D.A. Lane Thrombomodulin is a principle thrombin receptor located on the vascular endothelium. Thrombomodulin alters the specificity of thrombin, redirecting its procoagulant function to an anticoagulant function by making it a more efficient activator...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1997) 27 (2): 57–64.
Published Online: 28 April 2009
...Hasenqiqigel Qi; Takatoshi Koyama; Kenji Nishida; Nobuyuki Miyasaka; Shinsaku Hirosawa We characterized a factor important for the normal procoagulant activity in human urine and measured urinary tissue factor (TF) and thrombomodulin (TM) levels in patients with diabetes mellitus (DM). Urine...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1993) 23 (Suppl. 1): 183–193.
Published Online: 28 April 2009
...Evan Sadler; Steven R. Lentz; John P. Sheehan; Manuel Tsiang; Qingyu Wu Thrombomodulin is an anticoagulant protein cofactor that modulates the substrate specificity of thrombin and promotes the cleavage of protein C. The structure-function relationships of the thrombin-thrombomodulin interaction...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1990) 20 (Suppl. 1): 14–29.
Published Online: 24 April 2009
... Protein C Protein S Thrombomodulin Abstract. Blood coagulation forms part of an integrated series of haemostatic reactions, involving plasma, platelet, and vascular components. Platelets adhere to damaged endothe­ lium or to subendothelium under the influence of adhesive proteins, and when activated...
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1988) 18 (4-6): 271–306.
Published Online: 24 April 2009
..., the mechanism of action of protease inhibitors such as antithrombin III, heparin cofactor II, or protease nexin I and their possible interaction with glycosaminoglycan components of the endothelial cells is critically summarized. Thrombin binding to endothelial cells, in particular to thrombomodulin...
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Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (2005) 34 (2-3): 135–142.
Published Online: 26 January 2006
... simulations. The vessel was simulated as a two-dimensional channel of constant width, and the anticoagulant influence of thrombomodulin present on the undamaged vessel wall was taken into account. The results of the simulations showed that this inhibition could stop the coagulation process in the absence...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (2000) 30 (Suppl. 2): 34–40.
Published Online: 17 November 2004
.... 17 11 2004 Thrombosis Inflammation Coagulation Thrombomodulin Endothelial cell protein C receptor Main Paper Haemostasis 2000;30(suppl 2):34 40 Does Inflammation Contribute to Thrombotic Events? Charles T. Esmon Oklahoma Medical Research Foundation, Departments of Pathology...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (2003) 33 (1): 4–15.
Published Online: 08 August 2003
... of platelet inhibitors (e.g. aspirin and abciximab). Addition of activated protein C (APC) or thrombomodulin inhibits thrombin generation and reflects disorders of the APC system (congenital and acquired resistance, deficiencies and lupus antibodies) independent of concomitant inhibition of the procoagulant...
Journal Articles