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1-17 of 17
Keywords: Thrombocytopenia
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Journal Articles
Successful Administration of Low Molecular Weight Heparin in a Patient with Heparin-lnduced Thrombocytopenia and Coumarin-lnduced Skin Necrosis
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Pathophysiology of Haemostasis and Thrombosis (1993) 23 (5): 259–262.
Published Online: 28 April 2009
...P. Drakos; B. Uziely; A. Nagler; S. Gillis; A. Eldor A case of heparin-induced thrombocytopenia and skin necrosis induced by coumarin is reported in a 58-year-old female patient suffering from metastatic breast adenocarcinoma and deep vein thrombosis. The thrombosis resolved after treatment...
Journal Articles
The Influence of Heparin and Protamine Sulfate on Platelet ADP and Platelet Factor 4 Release and the Expression of Glycoprotein llb/llla
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Pathophysiology of Haemostasis and Thrombosis (1994) 24 (6): 358–363.
Published Online: 28 April 2009
...J. Storck; N. Höllger; R.E. Zimmermann We present results concerning the pathogenic mechanism of heparin-induced thrombocytopenia type I. An ELISA was developed for directly measuring the expression of glycoprotein IIb/IIIa (GPIIb/IIIa) on platelets in the presence and absence of ADP and under...
Journal Articles
Prediction of the Transfusion Effect of Platelet Concentrates as Measured by a Model of Primary Hemostasis ex vivo
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Pathophysiology of Haemostasis and Thrombosis (1997) 27 (2): 99–104.
Published Online: 28 April 2009
...M.A.A. Kratzer; K. Storck; J. Groh A method to determine primary hemostasis ex vivo (Thrombostat) was modified to monitor the transfusion effect of platelet concentrates (PC) in 12 patients with thrombocytopenia following bone marrow transplantation. It was possible to measure platelet function...
Journal Articles
Clinical Experience with Recombinant Factor VIla in Patients with Thrombocytopenia
Available to PurchaseJörgen Kristensen, Andreas Killander, Erik Hippe, Carsten Helleberg, Jörgen Ellegård, Mette Holm, Jack Kutti, Ulf-Henrik Mellqvist, Jan Erik Johansson, Steven Glazer, Ulla Hedner
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 1): 159–164.
Published Online: 28 April 2009
... reported to occur within the bleeding time wound and infusion of recombinant FVIIa (rFIIa) has been shown to shorten the bleeding time in rabbits. We have investigated whether infusion of rFVIIa would enhance fibrin formation in bleeding time wounds in patients with thrombocytopenia as reflected...
Journal Articles
Location of the Quinine-Dependent Epitope on Platelet Glycoprotein IlIa
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Pathophysiology of Haemostasis and Thrombosis (1991) 21 (5): 293–299.
Published Online: 24 April 2009
...Sharron L. Pfueller; Fernando Cortizo; Jannine Gibson; Robyn Bilston; Ian G. Sloan Quinine-dependent (Q) IgG antibodies (Q.Ab) in drug-induced immune thrombocytopenia are heterogeneous and bind to different platelet surface glycoproteins (GP), namely GPIb, IX, lIb, IlIa and an unidentified 57-kDa...
Journal Articles
Increased Plasma Tissue-Type Plasminogen Activator Levels in Patients with Chronic Thrombocytopenia
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Pathophysiology of Haemostasis and Thrombosis (1990) 20 (6): 341–346.
Published Online: 24 April 2009
...M. Hanss; D. Ville; M. Dechavanne Plasma fibrinolytic factors were measured in 14 patients with chronic idiopathic thrombocytopenic purpura (ITP), in 5 patients with chronic central thrombocytopenia and in 16 healthy volunteers. The von Willebrand factor (vWF), tissue-type plasminogen activator (t...
Journal Articles
Detection of Drug-Dependent IgG Antibodies with Antiplatelet Activity by the Antiglobulin Consumption Assay
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Pathophysiology of Haemostasis and Thrombosis (1984) 14 (6): 480–486.
Published Online: 21 April 2009
...L. Conti; P. Fidani; A. Chistolini; M. Francesconi; G.M. Gandolfo; M.G. Mazzucconi Drug-induced thrombocytopenia is a common acquired hemorrhagic disorder. In this study 32 patients with drug-induced thrombocytopenia were examined with the anti-globulin consumption assay. Platelet-associated IgG...
Journal Articles
Platelet Malondialdehyde Production Kinetics after Cyclooxygenase Block: A Study Performed with a Modified High Sensitivity Assay
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Pathophysiology of Haemostasis and Thrombosis (1983) 13 (1): 53–60.
Published Online: 17 April 2009
... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Platelets Malondialdehyde Platelet survival Thrombocytopenia Chronic obstructive pulmonary disease Haemostasis 13: 53-60 (1983) © 1983 S...
Journal Articles
Ditazole and Platelets: III. Effect of Ditazole on Tumor-Cell Induced Thrombocytopenia and on Bleeding Time in Mice
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Pathophysiology of Haemostasis and Thrombosis (1977) 6 (4): 260–265.
Published Online: 16 April 2009
... not be observed when the number of circulating platelets dropped slowly following intramuscular implantation and spontaneous dissemination of the same cancer cells. These results support previous observations suggesting a different mechanism for the thrombocytopenia observed after intravenous and intramuscular...
Journal Articles
Thrombocytopenia and Coagulation Impairment after Portacaval Shunt in the Rat
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Pathophysiology of Haemostasis and Thrombosis (1978) 7 (1): 19–25.
Published Online: 16 April 2009
...M.G. Doni; P. Vassanelli; L. Bonadiman; G.L. Avventi A study has been performed to evaluate the effect of the portacaval shunt on some coagulation tests in the rats. Thrombocytopenia develops, accompanied by a decrease in the total protein and fibrinogen concentrations. Moreover, the Quick time...
Journal Articles
Frequency of Anti-Heparin-PF4 Complex Antibodies (HIT Antibodies) in Uremic Patients on Chronic Intermittent Hemodialysis
Available to PurchaseTakefumi Matsuo, Hiroko Kobayashi, Miyako Matsuo, Keiko Wanaka, Hidetomo Nakamoto, Hiroyuki Matsushima, Rumi Sakai
Pathophysiology of Haemostasis and Thrombosis (2006) 35 (6): 445–450.
Published Online: 06 January 2009
... unfractionated heparin or low-molecular-weight heparin for 3 months. Heparin-induced thrombocytopenia (HIT) antibodies were detected by ELISA in 7 patients (2.3%) who had no history of HIT. Two patients abruptly developed HIT associated with the formation of clots in the extracorporeal circuit after they were...
Journal Articles
Laparoscopic Splenectomy for Immune Thrombocytopenic Purpura in Patients with Severe Refractory Thrombocytopenia
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Pathophysiology of Haemostasis and Thrombosis (2003) 33 (2): 116–119.
Published Online: 19 November 2003
... ofHaemostasis andThrombosis Original Paper Pathophysiol Haemost Thromb 2003;33:116 119 DOI: 10.1159/000073856 Received: November 11, 2002 Accepted after revision: March 6, 2003 Laparoscopic Splenectomy for Immune Thrombocytopenic Purpura in Patients with Severe Refractory Thrombocytopenia Andrei Keidar Boaz...
Journal Articles
Treatment of Bleeding in Patients with Platelet Disorders: Is There a Place for Recombinant Factor VIIa?
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Pathophysiology of Haemostasis and Thrombosis (2002) 32 (Suppl. 1): 37–40.
Published Online: 24 May 2002
...Yves Laurian The mechanism of action of recombinant factor VIIa (rFVIIa), i.e. increased thrombin generation on the membrane of activated platelets, as well as the results from in vitro and ex vivo models of thrombocytopenia or inherited thrombocytopathia may support some potential of rFVIIa...
Journal Articles
Lebetin Peptides: Potent Platelet Aggregation Inhibitors
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Pathophysiology of Haemostasis and Thrombosis (2001) 31 (3-6): 207–210.
Published Online: 25 March 2002
.... They prevent collagen-induced thrombocytopenia in rats. N- and C-terminal-truncated synthetic L1γ (sL1γ; 11-mer) is less active in inhibiting platelet aggregation than the native peptide. Results from Ala scan studies of the sL1γ peptide indicated that replacement of the residues (P3, G7, P8, P9 or N10...
Journal Articles
Paroxysmal Nocturnal Hemoglobinuria and the Risk of Venous Thrombosis: Review and Recommendations for Management of the Pregnant and Nonpregnant Patient
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Pathophysiology of Haemostasis and Thrombosis (2000) 30 (3): 103–117.
Published Online: 15 September 2000
... the postpartum state for a combined event rate of 12.1% (95% CI 3.4–25.2), three of which resulted in death. The all-cause mortality rate was 20.8% (95% CI 7.3–39.0). Both anemia (event rate 72.7%, 95% CI 56.5–86.3), and thrombocytopenia (event rate 27.3%, 95% CI 13.7–43.5) were common, often necessitating red...
Journal Articles
Massive Intracranial Bleeding Requiring Emergency Splenectomy in a Patient with CMV-Associated Thrombocytopenia
Available to PurchaseAlexander Gural, Shmuel Gillis, Anna Gafanovich, Zvi Israel, Danna Wolf, Shlomo Pomeranz, Dina Ben-Yehuda
Pathophysiology of Haemostasis and Thrombosis (1998) 28 (5): 250–255.
Published Online: 07 July 1999
... developed massive intracranial bleeding. Despite an extremely low platelet count (2×10 9 /liter) which was refractory to platelet transfusions, successful emergency splenectomy was performed, with rapid resolution of the thrombocytopenia. Bleeding complications are extremely rare in viral-associated ITP...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1998) 28 (1): 37–44.
Published Online: 18 January 1999
... with thrombocytopenia or other hematologic diseases. The use of PEG-rHuMGDF should be safe and not cause an additional risk of thromboocclusive disease in these patients. 18 1 1999 1999 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may be translated...