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Keywords: Prothrombin
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Journal Articles
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1986) 16 (3-4): 227–238.
Published Online: 21 April 2009
...Ross T.A. MacGillivray; David M. Irwin Using recombinant DNA techniques, DNA fragments coding for bovine prothrombin mRNA have been cloned and characterized. Structural studies have revealed that prothrombin mRNA encodes a precursor protein having an amino-terminal extension of 43 amino acid...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1986) 16 (3-4): 193–215.
Published Online: 21 April 2009
...J.W. Suttie; P.C. Preusch Vitamin K is required as a cofactor for a microsomal enzyme that converts glutamyl residues in precursor proteins to γ-carboxyglutamyl residues in completed proteins. These residues are essential for the biological function of prothrombin, factors VII, IX, and X, protein C...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1981) 10 (2): 104–107.
Published Online: 17 April 2009
...M.H. Aurousseau; J.L. d’Angeli; F. Josso In patients with liver cirrhosis, a close relationship was observed between the respective levels of antithrombin III and prothrombin, both below 50% in 20 out 27 patients. The absence of any thrombotic complication, despite low plasma antithrombin III...
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1978) 7 (2-3): 85–91.
Published Online: 16 April 2009
...Nils Egberg; Kurt Bergström Chromogenic substrates were used to assay prekallikrein, prothrombin and factor X. Plasma prekallikrein was contact activated and allowed the splitting of HD-Pro-Phe-Arg-PNA which has a high affinity for plasma kallikrein. Prothrombin was assayed in various ways...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1972) 1 (5-6): 271–278.
Published Online: 15 April 2009
...Franco Schettini; Domenico de Mattia; Angela Mautone Three activities of factor II (prothrombin, prothrombin-coagulase and antigenic activity) have been evaluated in full-term newborns on the first 5 days of life. Prothrombin activity is similar to prothrombin-coagulase activity on the 1st day...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1972) 1 (5-6): 237–252.
Published Online: 15 April 2009
... factors remain free. On the basis of this effect, nearly complete separation can be achieved. The interaction between the factors and dextran blue decreases with increasing pH. 30 08 1973 25 09 1973 15 4 2009 Dextran blue Prothrombin Factor II, VII, IX, X Purification Human...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1972) 1 (1): 2–22.
Published Online: 15 April 2009
.... Purification Prothrombin Factor VII Factor IX Factor X Bovine plasma Haemostasis 1: 2-22 (1972) Purification of Blood Coagulation Factors II, VII, IX and X from Bovine Citrated Plasma1 P. Reekers2 and H .C .H emker Department of Internal Medicine, Laboratories of Cardiobiochemistry and Blood...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1974) 3 (3): 158–166.
Published Online: 15 April 2009
...H. Ekert; M. Sheers Multiple components of the fibrinolytic mechanism (plasminogen, plasmin, antiplasmin, fibrinogen, fibrin degradation products) and factor II (prothrombin) levels were studied in 40 children with cyanotic congenital heart disease (CCHD) prior to corrective surgery. Seven...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (2005) 34 (4-5): 160–163.
Published Online: 19 May 2006
...Russolina B. Zingali; Marcos S. Ferreira; Mariane Assafim; Flávia S. Frattani; Robson Q. Monteiro Bothrojaracin (BJC) is a selective and potent thrombin inhibitor ( K D = 0.6 n M ) which also binds to prothrombin on proexosite I ( K D = 175 n M ). Incubation of BJC with human or rat plasma produced...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (2001) 31 (3-6): 273–278.
Published Online: 25 March 2002
... (proexosite I) on human prothrombin (K D = 75 n M) , forming a 1:1 Ca 2+ -independent noncovalent complex with the zymogen. Complex formation was associated with inhibition of zymogen activation by Oxyuranus scutellatus venom. In addition, BJC strongly decreased the prothrombin activation by factor Xa only...