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Keywords: Protein S
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Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1992) 22 (4): 165–172.
Published Online: 28 April 2009
... cell lines (HepG2, CAPAN-2 and J82) to support the inactivation of human factor Va by human APC in the presence and absence of human protein S. APC-mediated factor Va inactivation on these tumor cell lines was assessed by measuring the ability of residual cell-bound factor Va to augment the proteolytic...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (6): 304–310.
Published Online: 28 April 2009
...) in remission. The results obtained were compared with normal values obtained in healthy age- and sex-matched controls (n = 103). During relapse, there was a marked increase in the plasma level of fibrinogen, protein C, and protein S and reduced plasma ATIII level; tPA level was similar to control but PAI level...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1997) 27 (1): 25–34.
Published Online: 28 April 2009
...-binding protein (C4BP). We have recently shown that in some acute-phase patients C4BP is incorrectly controlled (with elevation of the C4BPΒ-containing isoforms), leading to a potential hypercoagulable state by decreasing the plasma levels of free (active) protein S. Here we have studied whether patients...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1992) 22 (1): 12–16.
Published Online: 28 April 2009
..., antithrombin III (AT III), protein C (PC), protein S (PS), tissue plasminogen activator (tPA), and plasminogen activator inhibitor (PAI) were done. Results indicated that all patients had prolonged ELT, low tPA, elevated PAI, normal AT III, and PS. Three patients had elevated fibrinogen level and two had low...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1993) 23 (2): 98–103.
Published Online: 28 April 2009
...P.T. Turkington Human polymorphonuclear leukocyte cathepsin G was used in vitro to digest human protein S. While clotting assays indicated that the proteinase induced a rapid decrease in activity, polyacrylamide gel electrophoresis-sodium dodecyl sulphate indicated the removal of a peptide of low...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1993) 23 (3): 142–148.
Published Online: 28 April 2009
.... There was a shift in protein S to the complexed inactive form, and the thrombin-antithrombin complexes increased. These changes occurred in parallel to both activation and inhibition of fibrinolysis. These changes were more pronounced in the septic shock patients than in nonshock neonates. After therapy...
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1990) 20 (Suppl. 1): 14–29.
Published Online: 24 April 2009
... Protein C Protein S Thrombomodulin Abstract. Blood coagulation forms part of an integrated series of haemostatic reactions, involving plasma, platelet, and vascular components. Platelets adhere to damaged endothe­ lium or to subendothelium under the influence of adhesive proteins, and when activated...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1988) 18 (4-6): 271–306.
Published Online: 24 April 2009
..., is believed to be a major event in the induction of anticoagulatory mechanisms such as the protein C/protein S system which warrant a balanced hemostatic system. Additional components such as vascular anticoagulant or extrinsic pathway inhibitor may also contribute to the anticoagulant potential of the vessel...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1988) 18 (4-6): 202–214.
Published Online: 24 April 2009
...David M. Stern; Evan Kaiser; Peter P. Nawroth The endothelium plays an active role in the regulation of the coagulation mechanism. Multiple anticoagulant properties are operative on the cell surface in homeostasis. In the protein C/protein S pathway, for example, endothelium provides cofactors...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1985) 15 (4): 241–246.
Published Online: 21 April 2009
...R.M. Bertina Protein S is a vitamin K-dependent plasma protein that serves as a cofactor of activated protein C (APC) in its inhibitory action on activated factor V and factor VIII and in its stimulation of fibrinolytic activity. In plasma, part of the protein S is complexed with the C4b-binding...
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1998) 28 (6): 307–312.
Published Online: 11 August 1999
... functional activities and plasma antigenic levels of coagulation inhibitors (antithrombin III, heparin cofactor II, protein C, and protein S) and plasma levels of C4b-binding protein were measured in 28 diabetic patients (13 males, 15 females; 2 IDDM, 26 NIDDM; median age 56.5 years; median duration...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1998) 28 (1): 25–30.
Published Online: 18 January 1999
... to congenital protein S deficiency. This article addresses the association of hereditary protein S deficiency and warfarin skin necrosis, and provides suggestions for management. 18 1 1999 1999 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...