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Keywords: Protein C
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Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1993) 23 (3): 142–148.
Published Online: 28 April 2009
... J. Romana F. Velascoa F. Fernandezb M. Fernandeza R. Villalbaa V. Rubioa A. Vicentea A Torresa Departments of a Hematology and b Pediatrics, Research Unit, Hospital Universitario Reina Sofia , Cordoba, Spain KeyW ords Neonatal sepsis Kallikrein system Protein S Protein C Fibrinolysis Coagulation...
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1992) 22 (6): 340–344.
Published Online: 28 April 2009
.... In the present study we evaluated protein C level in the plasma of patients with liver cell damage due to chronic alcohol consumption. A decrease in plasma protein C concentration which correlated with clinical performance of the patients was found. Significant correlations between the level of protein C...
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1994) 24 (1): 36–48.
Published Online: 28 April 2009
... was demonstrated with particularly marked reduction in fibrinolytic activity [drop of antithrombin III (ATIII) and protein C with an increase of plasminogen activator inhibitor (PAI-1) levels] which were directly correlated with the severity of the inflammatory state. Both ATIII and PAI-1 levels were correlated...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (6): 304–310.
Published Online: 28 April 2009
...) in remission. The results obtained were compared with normal values obtained in healthy age- and sex-matched controls (n = 103). During relapse, there was a marked increase in the plasma level of fibrinogen, protein C, and protein S and reduced plasma ATIII level; tPA level was similar to control but PAI level...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1997) 27 (3): 112–118.
Published Online: 28 April 2009
...David Green; Kochurani Maliekel; Elena Sushko; Rasheed Akhtar; Gerald A. Soff Background : Resistance to activated protein C (aPC) is usually linked to factor V Leiden, but may occur in other disorders associated with hypercoagulability. In this study, we investigated the frequency of resistance...
Journal Articles
Journal Articles
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1993) 23 (Suppl. 1): 183–193.
Published Online: 28 April 2009
...Evan Sadler; Steven R. Lentz; John P. Sheehan; Manuel Tsiang; Qingyu Wu Thrombomodulin is an anticoagulant protein cofactor that modulates the substrate specificity of thrombin and promotes the cleavage of protein C. The structure-function relationships of the thrombin-thrombomodulin interaction...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1992) 22 (1): 12–16.
Published Online: 28 April 2009
..., antithrombin III (AT III), protein C (PC), protein S (PS), tissue plasminogen activator (tPA), and plasminogen activator inhibitor (PAI) were done. Results indicated that all patients had prolonged ELT, low tPA, elevated PAI, normal AT III, and PS. Three patients had elevated fibrinogen level and two had low...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1996) 26 (Suppl. 4): 9–19.
Published Online: 28 April 2009
...Martine Aiach; Sophie Gandrille The clinical presentation of hereditary protein C deficiency is highly variable. Homozygosity and compound heterozygosity have been linked to severe thrombotic complications early in the life. Heterozygous patients have a moderate form of the disease with deep venous...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1989) 19 (1): 45–50.
Published Online: 24 April 2009
...O. Takamiya; S. Kinoshita; K. Niinomi; K. Yoshioka Protein-C activity and antigen were measured in 141 full-term infants during the first month of life. The levels of both protein-C activity and antigen were about one third the level for normal adults in cord blood, and significantly lower than...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1989) 19 (Suppl. 1): 24–28.
Published Online: 24 April 2009
... found reduced antithrombin III and factor VII levels in all the patients, in line with the results of other authors, and other slight and less constant changes such as lowered factor X activity and protein C antigen, and increased β-thromboglobulin levels. During pyridoxine and folate treatment...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1990) 20 (Suppl. 1): 14–29.
Published Online: 24 April 2009
... Protein C Protein S Thrombomodulin Abstract. Blood coagulation forms part of an integrated series of haemostatic reactions, involving plasma, platelet, and vascular components. Platelets adhere to damaged endothe­ lium or to subendothelium under the influence of adhesive proteins, and when activated...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1991) 21 (Suppl. 1): 161–167.
Published Online: 24 April 2009
... substrates, hirudin may serve to discriminate between actions mediated by thrombin, its precursors, cofactors and effectors and actions of other enzyme systems. The principle of this hirudin application is exemplified for factor-V- and factor-VIII-dependent anticoagulant activity of protein C. 24 4...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (1985) 15 (4): 233–240.
Published Online: 21 April 2009
...A.W. Broekmans Hereditary protein C deficiency, which is inherited as an autosomal-dominant trait, predisposes to venous thrombotic disease. Heterozygotes are at risk for superficial thrombophlebitis, deep venous thrombosis and/or pulmonary embolism, which may occur without apparent cause...
Journal Articles
Pathophysiology of Haemostasis and Thrombosis (2000) 30 (Suppl. 2): 26–33.
Published Online: 17 November 2004
... the risk of venous thrombosis. Hyperlipidaemia is associated with hypercoagulability, and lipoproteins exhibit procoagulant (e.g. triglyceride-rich particles and oxidized low-density lipoprotein) or anticoagulant (e.g. high-density-lipoprotein’s cofactor activity for activated protein C/protein S...
Journal Articles