...M. Köhler; P. Hellstern; H. Tarrach; R. Bambauer; E. Wenzel; G.A. Jutzler A more concentrated desmopressin (DDAVP) preparation (40 µg/ml), which required small injection volumes (< 1 ml), was studied in a double-blind trial in 10 healthy volunteers, 12 patients with haemophilia A, and 8 patients...

...W.M. Smid; J. van der Meer; M.R. Halie The efficacy and safety of a monoclonal purified factor VIII concentrate (Hemofil M) were assessed in a historically controlled study in 22 HIV-negative patients with haemophilia A, previously treated with various concentrates. Data from 5 years of follow-up...

...Stefan Neuenschwander; Vladimir Pliška The sheep haemophilia A, recently described in a flock of White Alpine sheep, is probably caused by the production of a less potent mutant of factor VIII (F-VIII). Other potential mechanisms, such as drastic reduction (or lack) of F-VIII production...

...H.-H. Brackmann; H.J. Eickhoff; J. Oldenburg; U. Hammersterin Between 1978 and 1989, a controlled study was performed on children and adolescents suffering from severe haemophilia A. Special attention was given to long-term therapy adjusted to the patients’ requirements. The clinical and the X-ray...

...Osman Aden Abdulle; Mohamud Sahid Mohamud; Maryan Mohamed Isse; A. Chistolini; M. Papacchini; G. Mariani As first step for the development of a programme of haemophilia care, the disease was diagnosed locally in 5 bleeders. These patients were all affected by severe haemophilia A. They were treated...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Plasmapheresis Haemophilia A Factor VIII antibody Spontaneous factor VIII antibody Anamnestic rise Haemostasis II: 79-86 (1982) Plasmapheresis: Its Value...

... against factor VIII-related antigen (F-VIII-RA). Specific staining was observed in platelets of the peripheral blood from normal individuals and from patients with haemophilia A, and in megakaryocytes and platelets of bone marrow from normal subjects. The same cells studied in patients with von...

...L. Dintenfass; C.D. Forbes Dynamic coagulation-thrombus formation studies and evaluation of the aggregation of red cells, plasma viscosity and blood viscosity were carried out on 22 patients with haemophilia A and 6 patients with Christmas disease. Significant differences are found in the formation...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. FEIBA Factor VIIa Haemophilia A Inhibitor Thrombin generation Prothrombinase Activated prothrombin complex Pathophysiology ofHaemostasis andThrombosis Pathophysiol Haemost...

...Susan Schonfield; Keith Reid The Pan-Thames Haemophilia Consortium was established to provide coherent regional planning of haemophilia services. The Expert Advisory Group is a clinical reference point for the consortium and was established to consider specifically elective high cost treatment...

...Karin E. Knobe; Bruno O. Villoutreix; Lilian I. Tengborn; Pia Petrini; Rolf C.R. Ljung The development of inhibitory antibodies against coagulation factor VIII (FVIII) in patients with mild haemophilia A is uncommon. We describe here two families in which three or two members have developed...