...M. Vasse; J. Paysant; J. Soria; J.P. Collet; J.P. Vannier; C. Soria High level of fibrinogen in plasma is recognised as an important vascular risk factor. However, it is not known if the increase in fibrinogen is directly responsible for the vascular risk or is a marker of vascular inflammation...

... in both groups were very high levels of fibrinogen, lipoprotein(a), serum cholesterol, and LDL cholesterol. 30 12 1993 7 02 1994 28 4 2009 © 1994 S. Karger AG, Basel 1994 Copyright / Drug Dosage / Disclaimer Copyright: All rights reserved. No part of this publication may...

... for single-chain tPA and Lys 78 -plg, and was enhanced approximately 5-fold by fibrinogen and 17-fold by polymerized fibrin. Kapp was (1.57 ± 0.46) × 10 3 / M /s for two-chain tPA and Lys 78 -plg, and was enhanced approximately 2.6-fold by fibrinogen and 3.6-fold by fibrin. The factor of the enhancement...

... thrombin inhibitor recombinant hirudin to prevent TF-induced coagulation activation in a rabbit model. Infusion of 0.5 μg·kg –1 •h –1 TF in rabbits for 7 h led to a decrease in fibrinogen and platelets, to an increase in fibrin monomers and to a prolongation of TT, aPTT and PT. Recombinant hirudin...

...Hester Vorster; Johann Jerling; Welma Oosthuizen; John Cummings; Sheila Bingham; Liz Magee; Angela Mulligan; Shirley Runswick The hypothesis that tea drinking may protect against coronary heart disease (CHD) through effects on clotting as measured by plasma fibrinogen, tissue-type plasminogen...

... with intermittent claudication. One hundred and thirty men at high cardiovascular risk and 51 men at low risk were examined. The subjects (high- and low-risk) with moderate/large plaque (n = 96) had higher fibrinogen, thrombin/antithrombin complex and von Willebrand factor, compared to subjects with small/no plaque...

...Domenico Prisco; Nicoletta Zarone; Agatina Alessandrello Liotta; Anna P. Cellai; Paolo Comeglio; Sandra Fedi; Isa Francalanci; Rosanna Abbate The measurement of fibrinogen (Fg) plasma levels is one of the more frequently performed tests in clinical practice, usually by clotting assay. However...

... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Deep vein thrombosis Diagnosis Review Venography Ultrasonic imaging Impedance plethysmography Thermography Fibrinogen Blood tests Haemostasis 1995;25:6-26 H...

...Paolo Pasqualetti; Vittorio Festuccia; Pierluigi Acitelli; Laura Natali; Antonio Collacciani; Raffaele Casale Acquired deficiencies of fibrinogen, antithrombin III and plasminogen are reported in liver disease, and it is known that their plasma levels fluctuate during the day. The aim of this study...

...Jens V. Sørensen; Hans P. Jensen; Hans B. Rahr; Lars C. Borris; Michael R. Lassen; Ole Fedders; Jens P. Haase; Flemming Knudsen In a prospective study including 30 traumatized patients, levels of fibrinogen, fibrinopeptide A (FpA), fibrin monomers (FM) and fibrin degradation products (FbDP) were...

...M. Walzl; P. Lechner; B. Walzl; H. Lechner; H. Cesnik The heparin-induced extracorporeal low-density lipoprotein (LDL) precipitation (HELP) system is based on the fact that besides lipoproteins even fibrinogen, which seems to be a very important factor in pathogenesis of peripheral arterial disease...

...M. Walzl The effects of heparin-mediated extracorporeal low-density lipoprotein (total cholesterol, lipoprotein (a), triglycerides, fibrinogen) precipitation (HELP) and bezafibrate on fibrinogen, metabolic parameters, hemorheological patterns and clinical symptoms were studied in 40 patients...

...Walter-Michael Halbmayer; Alexander Haushofer; Renate Schön; Johannes Radek; Michael Fischer A new automated kinetically determined fibrinogen assay was measured in plasmas of healthy subjects and three clinical cohorts (acute-phase reaction, liver cirrhosis and fibrinolytic therapy) that were...

...Vicenta Martínez-Sales; Virtudes Vila; Edelmiro Réganon; Justo Aznar The binding of unstimulated and thrombin-stimulated platelets was studied with immobilized fibrinogen and fibrin on polystyrene. The amount of fibrinogen bound to the polystyrene support was 2 μg/tube, which represents 2.35 μg/cm...

...F. Marongiu; A.M. Mamusa; P. Dessalvi; G. Mameli; A.B. Cambuli; G.G. Sorano; M. Conti; P. Farci; A. Balestrieri In order to investigate whether high fibrinogen levels were associated with elevated thrombin activity, we measured fibrinogen and fibrinopeptide A in 37 elderly healthy subjects ranging...

...M. Borrell; Ll. Vila; J. Solá; I. Coll; J. Fontcuberta We describe a new congenital dysfibrinogenemia: fibrinogen Barcelona II in 8 members of a family with no major bleeding or thrombotic tendency. Incubation of this fibrinogen with thrombin at low concentration releases half of the expected...

...Elisabetta Dejana; Adriana Zanetti; Grazia Conforti Several observations indicate that endothelial cells interact with fibrinogen, fibrin, and their derivative products. The main biological function of fibrinogen on endothelial cells so far identified is its ability to promote adhesion, motility...

..., except for a significant drop in fibrinogen during therapy and for 1 week after stopping the drug. The lack of any antiplatelet action and minimal effects on the coagulation parameters recommend the drug as a suitable antirheumatic in patients with bleeding disorders. The hypofibrinogenaemic action...

.... The best-fit kinetic model for the release of FPAP and FPAY is consistent with a simple pseudo first-order reaction, as observed with FPA. These findings indicate that FPAP and FPAY are also released from intact fibrinogen before release of FPB. The values of the specificity constants, i.e. k at /K m...

... of fibrin resulted in a decrease in K m , whereas the presence of larger amounts of fibrin resulted in an increase in k cat with a slight decrease in K m . The presence of fibrinogen also enhanced the activation of Glu-Plg by t-PA with an increase in k cat and without change in K m . When the effects...